Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Chung-Liang Ho"'
Autor:
Jui-Hsiang Hung, Chiao-Feng Teng, Hsu-chin Hung, Yi-Lin Chen, Pin-Jun Chen, Chung-Liang Ho, Cheng-Hsiang Chuang, Wenya Huang
Publikováno v:
Annals of Hepatology, Vol 29, Iss 6, Pp 101546- (2024)
Hepatocellular carcinoma (HCC) is one of the deadliest cancers. For patients with advanced HCC, liver function decompensation often occurs, which leads to poor tolerance to chemotherapies and other aggressive treatments. Therefore, it remains critica
Externí odkaz:
https://doaj.org/article/b460dbfd7d9c46aeb5748eecc28d1da8
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background The Wnt/β-catenin signaling pathway plays an important role in embryogenesis and tumorigenesis. In human cancer, abnormal activity of Wnt/β-catenin signaling pathway induces overexpressed of downstream genes, and initiate oncoge
Externí odkaz:
https://doaj.org/article/d9be3f213df643e782693d2f3cc63b70
Autor:
Po-Lan Su, Jung-Yueh Chen, Chang-Yao Chu, Yi-Lin Chen, Wan-Li Chen, Kuan-Yu Lin, Chung-Liang Ho, Jeng-Shiuan Tsai, Szu-Chun Yang, Chian-Wei Chen, Yi-Lin Wu, Yau-Lin Tseng, Chao-Chun Chang, Yi-Ting Yen, Chia-Ying Lin, Chien-Chung Lin, Wu-Chou Su
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Neoadjuvant immunotherapy and chemotherapy have improved the major pathological response (MPR) in patients with early-stage operable non-small cell lung cancer (NSCLC). This study aimed to assess whether the presence of targetable driver mut
Externí odkaz:
https://doaj.org/article/249de0c14737440c9d0617b01e951b12
Autor:
Wenya Huang, Chung-Liang Ho, Chung-Ta Lee, Wan-Li Chen, Shu-Ching Yang, Nan-Haw Chow, Yi-Lin Chen
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Microsatellite instability (MSI) is the primary predictive biomarker for therapeutic efficacies of cancer immunotherapies. Establishment of the MSI detection methods with high sensitivity and accessibility is important. Because MSI is mainly caused b
Externí odkaz:
https://doaj.org/article/2c4c51d996cd443ab7889acbb3dda7a4
Autor:
Yi-Lin Chen, Chung-Liang Ho, Chen-Yan Hung, Wan-Li Chen, Chen Chang, Yi-Hsin Hou, Jian-Rong Chen, Pin-Jun Chen, Nan-Haw Chow, Wenya Huang, Ya-Ting Hsu, Tsai-Yun Chen, Tsunglin Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Clonality assessment, which can detect neoplastic T cells by identifying the uniquely recombined T-cell receptor (TCR) genes, provides important support in the diagnosis of T-cell lymphoma (TCL). BIOMED-2 is the gold standard clonality assay and has
Externí odkaz:
https://doaj.org/article/7be49aa75398497dad4bbbabdf9a2e0d
Autor:
Chien-Yu Lin, Sheng-Huan Wei, Yi-Lin Chen, Chung-Ta Lee, Shang-Yin Wu, Chung-Liang Ho, Dean C. Pavlick, Po-Lan Su, Chien-Chung Lin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Telisotuzumab vedotin is a MET-targeting antibody–drug conjugate that has demonstrated a good treatment response in patients with EGFR wild-type MET-overexpressing non-squamous non-small cell lung cancer. However, patients have been reported to acq
Externí odkaz:
https://doaj.org/article/c5d82a14666246079097088647b395c1
Autor:
Tsunglin Liu, Cheng-Han Lin, Yi-Lin Chen, Shuen-Lin Jeng, Hui-Ju Tsai, Chung-Liang Ho, Wen-Shuo Kuo, Miao-Hsi Hsieh, Pei-Chi Chen, Lawrence Shih-Hsin Wu, Jiu-Yao Wang
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Airway and gut microbiota are important in asthma pathogenesis. Although several studies have revealed distinct microbiota in asthmatic airways at baseline compared to healthy controls, limited studies compared microbiota during acute exacerbation (A
Externí odkaz:
https://doaj.org/article/d5e49274bcf3460c82247622c565d28b
Autor:
Po‐Lan Su, Szu‐Chun Yang, Yi‐Lin Chen, Yi‐Lin Wu, Chia‐Ying Lin, Wei‐Yuan Chang, Yau‐Lin Tseng, Wu‐Wei Lai, Chung‐Liang Ho, Chien‐Chung Lin, Wu‐Chou Su
Publikováno v:
Cancer Medicine, Vol 8, Iss 13, Pp 5939-5947 (2019)
Abstract Background Osimertinib yields significant tumor responses and durations of progression‐free survival (PFS) in patients with acquired T790M mutations. However, the evidence supporting liquid biopsy‐guided treatment is still limited. This
Externí odkaz:
https://doaj.org/article/fb79b51197984d75892ed6f10ff260d5
Autor:
Yi-Lin Chen, Wan-Li Chen, Yi-Chia Cheng, Ming-Ching Lin, Shu-Ching Yang, Hung-Wen Tsai, Chien-Chung Lin, Wu-Chou Su, Nan-Haw Chow, Chung-Liang Ho
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257152 (2021)
Approximately 5-7% of non-small cell lung cancer (NSCLC) cases harbor an anaplastic lymphoma kinase (ALK) fusion gene and may benefit from ALK inhibitor therapy. To detect ALK fusion genes, we developed a novel test using reverse transcription polyme
Externí odkaz:
https://doaj.org/article/f237227974f540cd9dec0686f2f84839
Autor:
Yi-Lin Chen, Chien-Chung Lin, Shu-Ching Yang, Wan-Li Chen, Jian-Rong Chen, Yi-Hsin Hou, Cheng-Chan Lu, Nan-Haw Chow, Wu-Chou Su, Chung-Liang Ho
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Third-generation tyrosine kinase inhibitors (TKIs) were developed to overcome T790M-mediated resistance to earlier generations of epidermal growth factor receptor (EGFR)-targeted TKIs. We compared four well-established and one in-house method for the
Externí odkaz:
https://doaj.org/article/4d445a92355640e0a8207cd5b957c13c