Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chung-Ching Chu"'
Autor:
Prudence PokWai Lui, Chrysanthi Ainali, Chung-Ching Chu, Manuela Terranova-Barberio, Panagiotis Karagiannis, Angela Tewari, Niloufar Safinia, Ehsan Sharif-Paghaleh, Sophia Tsoka, Grzegorz Woszczek, Paola Di Meglio, Giovanna Lombardi, Antony R. Young, Frank O. Nestle, Niwa Ali
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108029- (2023)
Summary: Skin immune homeostasis is a multi-faceted process where dermal dendritic cells (DDCs) are key in orchestrating responses to environmental stressors. We have previously identified CD141+CD14+ DDCs as a skin-resident immunoregulatory populati
Externí odkaz:
https://doaj.org/article/bfb8903d33a541d1b9febee12c9327fb
Autor:
Edries Yousaf Hajam, Patricia Panikulam, Chung-Ching Chu, Haarshadri Jayaprakash, Amitabha Majumdar, Colin Jamora
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As the interface between the body and the environment, the skin functions as the physical barrier against external pathogens and toxic agents. In addition, the skin is an immunologically active organ with a plethora of resident adaptive and innate im
Externí odkaz:
https://doaj.org/article/14fa586013ff47f1b3f34dfe456cb7b9
Autor:
Lu Wang, Yi-Ning Xu, Chung-Ching Chu, Zehua Jing, Yabin Chen, Jinsong Zhang, Mingming Pu, Tingyan Mi, Yaping Du, Zongqi Liang, Chandraprabha Doraiswamy, Tao Zeng, Jiarui Wu, Luonan Chen
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT Urban living has been reported to cause various skin disorders. As an integral part of the skin barrier, the skin microbiome is among the key factors associated with urbanization-related skin alterations. The role of skin microbiome in media
Externí odkaz:
https://doaj.org/article/e3bc26cf7f7a42c6acc24bc521897d6a
Autor:
Paola Di Meglio, Antonella Di Cesare, Ute Laggner, Chung-Ching Chu, Luca Napolitano, Federica Villanova, Isabella Tosi, Francesca Capon, Richard C Trembath, Ketty Peris, Frank O Nestle
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17160 (2011)
IL-23 and Th17 cells are key players in tissue immunosurveillance and are implicated in human immune-mediated diseases. Genome-wide association studies have shown that the IL23R R381Q gene variant protects against psoriasis, Crohn's disease and ankyl
Externí odkaz:
https://doaj.org/article/65d3ec30fdb44d5cb1064f1049b3c293
Autor:
Yousaf Hajam, Edries, Panikulam, Patricia, Chung-Ching Chu, Jayaprakash, Haarshaadri, Majumdar, Amitabha, Jamora, Colin
Publikováno v:
Frontiers in Immunology; 9/15/2022, Vol. 13, p1-15, 15p
Autor:
Chung-Ching Chu, Eva Cernuda-Morollón, Dela Golshayan, Marina I. Garin, Robert I. Lechler, Robin Wait
The naturally occurring population of dedicated regulatory T cells that coexpress CD4 and CD25 is known to play a key role in the maintenance of peripheral T-cell tolerance; however, their mechanism of action has remained obscure. Here we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc2d24e7b8a3db9d3405631be0e79e3
https://ora.ox.ac.uk/objects/uuid:0b08dfd4-8946-44b4-baba-4d8d580b0d75
https://ora.ox.ac.uk/objects/uuid:0b08dfd4-8946-44b4-baba-4d8d580b0d75
Publikováno v:
Seminars in Immunology
The skin immune system harbors a complex network of dendritic cells (DCs). Recent studies highlight a diverse functional specialization of skin DC subsets. In addition to generating cellular and humoral immunity against pathogens, skin DCs are involv
Autor:
Rosalind Foster, Christine L. Jones, Chung-Ching Chu, Isabella Tosi, Sean Whittaker, Robert C.T. McKenzie, E. Mary Wain, Tracey J. Mitchell
Publikováno v:
Journal of Investigative Dermatology. 130(4):1116-1125
Sezary Syndrome (SS) is an aggressive leukemic variant of primary cutaneous T-cell lymphoma characterized by the presence of tumor or Sezary cells that generally display a mature memory T-cell immunophenotype. Sezary cells proliferate poorly and ther
Autor:
Laura Gutierrez, Clive S. McKimmie, Gerard J. Graham, Giovanna Lombardi, Alasdair R. Fraser, Paz Carreno, Robert J. B. Nibbs, Iain B. McInnes, Chris A. H. Hansell, Laura Connell, Sjaak Philipsen, Christina Halsey, Monika Pruenster, Antal Rot, Foo Y. Liew, Chung-Ching Chu, Mariola Kurowska-Stolarska
Publikováno v:
The Journal of Immunology. 181:8170-8181
D6 scavenges inflammatory chemokines and is essential for the regulation of inflammatory and immune responses. Mechanisms explaining the cellular basis for D6 function have been based on D6 expression by lymphatic endothelial cells. In this study, we
Autor:
Niwa Ali, Luca Napolitano, Paola Di Meglio, Giovanna Lombardi, Panagiotis Karagiannis, Ehsan Sharif-Paghaleh, Sophia N. Karagiannis, Chung-Ching Chu, G. Barinaga, K. Grys, Ania Skowera, Mark Peakman, Frank O. Nestle
Publikováno v:
The Journal of Experimental Medicine
Human skin-resident IL-10+ regulatory dendritic cells induce T reg cells that suppress allogeneic skin graft inflammation.
Human skin immune homeostasis, and its regulation by specialized subsets of tissue-residing immune sentinels, is poorly un
Human skin immune homeostasis, and its regulation by specialized subsets of tissue-residing immune sentinels, is poorly un