Zobrazeno 1 - 10
of 9 251
pro vyhledávání: '"Chung YU"'
Autor:
Lisi Wei, Xiaoli Guo, Ehud Haimov, Kazuki Obashi, Sung Hoon Lee, Wonchul Shin, Min Sun, Chung Yu Chan, Jiansong Sheng, Zhen Zhang, Ammar Mohseni, Sudhriti Ghosh Dastidar, Xin-Sheng Wu, Xin Wang, Sue Han, Gianvito Arpino, Bo Shi, Maryam Molakarimi, Jessica Matthias, Christian A. Wurm, Lin Gan, Justin W. Taraska, Michael M. Kozlov, Ling-Gang Wu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-24 (2024)
Abstract Membrane budding, which underlies fundamental processes like endocytosis, intracellular trafficking, and viral infection, is thought to involve membrane coat-forming proteins, including the most observed clathrin, to form Ω-shape profiles a
Externí odkaz:
https://doaj.org/article/518300501f89466182891e0cc4c55801
Autor:
Ling-Gang Wu, Chung Yu Chan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Membrane fusion and budding mediate fundamental processes like intracellular trafficking, exocytosis, and endocytosis. Fusion is thought to open a nanometer-range pore that may subsequently close or dilate irreversibly, whereas budding trans
Externí odkaz:
https://doaj.org/article/df529918c30c422eaf56a49600515663
Autor:
Wonchul Shin, Ben Zucker, Nidhi Kundu, Sung Hoon Lee, Bo Shi, Chung Yu Chan, Xiaoli Guo, Jonathan T. Harrison, Jaymie Moore Turechek, Jenny E. Hinshaw, Michael M. Kozlov, Ling-Gang Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Shin et al. report the molecular mechanics of membrane budding: actin and dynamin pull membrane inward to form a Λ-shape profile; dynamin helices convert Λ- to Ω-shape by constricting Λ’s base, and then constrict Ω-profile’s pore to form a v
Externí odkaz:
https://doaj.org/article/52e7b54f554c4c94b750537319d58671
Spoken language models (SLMs) have gained increasing attention with advancements in text-based, decoder-only language models. SLMs process text and speech, enabling simultaneous speech understanding and generation. This paper presents Double-Codebook
Externí odkaz:
http://arxiv.org/abs/2410.24177
Large Language Models (LLMs) have demonstrated remarkable abilities across various tasks, leveraging advanced reasoning. Yet, they struggle with task-oriented prompts due to a lack of specific prior knowledge of the task answers. The current state-of
Externí odkaz:
http://arxiv.org/abs/2409.16418
Large Language Models (LLMs) have demonstrated impressive performance in software engineering tasks. However, improving their accuracy in generating correct and reliable code remains challenging. Numerous prompt engineering techniques (PETs) have bee
Externí odkaz:
http://arxiv.org/abs/2409.16416
Autor:
Jamin Liu, Kristeene A. Knopp, Elze Rackaityte, Chung Yu Wang, Matthew T. Laurie, Sara Sunshine, Andreas S. Puschnik, Joseph L. DeRisi
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is a well-studied mammarenavirus that can be fatal in congenital infections. However, our understanding of LCMV and its interactions with human host factors remains incomplete. Here, host determinant
Externí odkaz:
https://doaj.org/article/7c79b2d5e65341dd89b13a3d0e1b930a
Autor:
Ling-Gang Wu, Chung Yu Chan
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Cytoskeletal filamentous actin (F-actin) has long been considered a molecule that may regulate exo- and endocytosis. However, its exact roles remained elusive. Recent studies shed new light on many crucial roles of F-actin in regulating exo- and endo
Externí odkaz:
https://doaj.org/article/2d555fbdfd5e4755a02caf731408f9be
Autor:
Gianvito Arpino, Agila Somasundaram, Wonchul Shin, Lihao Ge, Seth Villareal, Chung Yu Chan, Uri Ashery, Oleg Shupliakov, Justin W. Taraska, Ling-Gang Wu
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103809- (2022)
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane. By employing conventional and platinum replica electron microscopy and super-resoluti
Externí odkaz:
https://doaj.org/article/b97afdad4fb9476ba4767ca24af811ab
Autor:
Cheng Chih Wu, Po Yen Chen, Shih Wei Wang, Meng Hsuan Tsai, Yu Chin Lily Wang, Ching Ling Tai, Hao Lun Luo, Hung-Jen Wang, Chung Yu Chen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Androgen deprivation therapy (ADT) suppresses the production of androgen, and ADT is broadly used for intermediate or higher risk disease including advanced and metastatic cancer. ADT is associated with numerous adverse effects derived fr
Externí odkaz:
https://doaj.org/article/328e9dc384a04dfb91a357d07e053d7f