Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chung Y. Lui"'
Autor:
J. H. Lin, Drazen Ostovic, Elisabeth R. Reiss, Alice E. Loper, I.-W. Chen, Linda B. Novak, Raymond J. Higgins, Lisa A. Hettrick, Gloria Kwei, Chung Y. Lui
Publikováno v:
Pharmaceutical Research. 12:884-888
Purpose. To evaluate regional intestinal absorption and the feasibility of sustained release dosage form development for an HIV protease inhibitor, L-735,524.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ede1e08619ad34fa46e27785b2ef194
https://doi.org/10.1023/a:1016269206048
https://doi.org/10.1023/a:1016269206048
Autor:
Gaylen M. Zentner, Gregory A. McClelland, Gerald S. Rork, James D. Pipkin, Lida Liu, Amy R. Coulter, J. Douglas Rogers, Michael S. Schwartz, Steven C. Sutton, Raju D. Amin, Jules I. Schwartz, Yale B. Mitchel, Haiyung Cheng, Chung Y. Lui, Kenneth Grasing, David L. Ebel, Karen Engle
Publikováno v:
Pharmaceutical Research. 10:1683-1687
Seven sustained/controlled-release dosage forms were designed for gastrointestinal delivery of lovastatin or simvastatin, two potent HMG-CoA reductase inhibitors for the treatment of hypercholesterolemia. The in vivo performance of these formulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecfdb7add32dac2ed025e3ebb2f3d0e
https://doi.org/10.1023/a:1018997308946
https://doi.org/10.1023/a:1018997308946
Publikováno v:
Journal of Pharmaceutical Sciences. 80:1125-1129
Intranasal delivery of flurazepam, midazolam, and triazolam was studied in a dog model as a possible alternate route of drug administration for treatment of insomnia. Four beagles received each hypnotic by both intranasal and oral routes on two separ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16a5f4f89bf37243e68c57002bf4034
https://doi.org/10.1002/jps.2600801207
https://doi.org/10.1002/jps.2600801207
Publikováno v:
Biopharmaceutics & Drug Disposition. 7:487-494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271e163685a29c49922812d3ce956774
https://doi.org/10.1002/bdd.2510070509
https://doi.org/10.1002/bdd.2510070509
Publikováno v:
Journal of Pharmaceutical Sciences. 70:109-112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7b85014d2c1b738739985ab08152ca
https://doi.org/10.1002/jps.2600700129
https://doi.org/10.1002/jps.2600700129
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 12:597-610
The effects of plasma concentration and pH on the steady-state volume of distribution, Vss, of methotrexate (MTX) were studied in five conditioned male beagle-mongrel dogs. Steady-state plasma MTX concentrations of approximately 1, 20, and 100 microg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b50e0553703e6d02096990ac6848aa8
https://doi.org/10.1007/bf01059555
https://doi.org/10.1007/bf01059555
Publikováno v:
Journal of pharmaceutical sciences. 75(5)
The bioavailability of enteric coated and plain aspirin tablets was studied in four beagle dogs. Blood sampling for enteric coated tablets was planned with the aid of a radiotelemetric system. The release of aspirin from its dosage form was detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f1d12a62b233a80d99d7f21b7acfb3
https://pubmed.ncbi.nlm.nih.gov/3735085
https://pubmed.ncbi.nlm.nih.gov/3735085
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 13(2)
The effects of urine flow and pH on methotrexate renal clearance were studied in seven conditioned male Beagle-Mongrel dogs. Steady-state plasma methotrexate and inulin concentrations were achieved by i.v. infusions preceded by i.v. bolus doses. Plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce792360a951063beda0927eb6d4e0f
https://pubmed.ncbi.nlm.nih.gov/4057055
https://pubmed.ncbi.nlm.nih.gov/4057055
Publikováno v:
Biopharmaceuticsdrug disposition. 7(4)
An evaluation of the literature indicated that certain aspects of the disposition kinetics of iothalamate, important to the accurate determination of glomerular filtration rate in dogs and humans, remain to be resolved. The simultaneous clearances of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34c42fa0b9a28eba6046583ee61e9eb
https://pubmed.ncbi.nlm.nih.gov/3768490
https://pubmed.ncbi.nlm.nih.gov/3768490
Autor:
Win L. Chiou, Chung Y. Lui
Publikováno v:
Biopharmaceuticsdrug disposition. 7(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad3b70be91b02f0088dcb1ab2b5578f
https://pubmed.ncbi.nlm.nih.gov/3730531
https://pubmed.ncbi.nlm.nih.gov/3730531