Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chung Y. Cheung"'
Autor:
Chung Y. Cheung, Sitara Dubey, Martina Hadrovic, Christina R. Ball, Walter Ramage, Jacqueline U. McDonald, Ruth Harvey, Simon E. Hufton, Othmar G. Engelhardt
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1473 (2022)
Inactivated vaccines are the main influenza vaccines used today; these are usually presented as split (detergent-disrupted) or subunit vaccines, while whole-virus-inactivated influenza vaccines are rare. The single radial immune diffusion (SRD) assay
Externí odkaz:
https://doaj.org/article/30c7f237bf71402782455202486336c6
Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma
Autor:
Anthony Tam, Emmanuel Twumasi Osei, Chung Y. Cheung, Michael Hughes, Chen X. Yang, Kelly M. McNagny, Delbert R. Dorscheid, Gurpreet K. Singhera, Teal S. Hallstrand, Stephanie Warner, James C. Hogg, Tillie L. Hackett, Chinten J. Lim, Don D. Sin
Publikováno v:
Cells, Vol 11, Iss 19, p 3016 (2022)
Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general population. It has also been shown that sonic hedgehog (SHH), an important ligand for PTCH1, i
Externí odkaz:
https://doaj.org/article/dd1914f393004b81bde0752df491967b
Autor:
Walter Ramage, Tiziano Gaiotto, Christina Ball, Paul Risley, George W. Carnell, Nigel Temperton, Chung Y. Cheung, Othmar G. Engelhardt, Simon E. Hufton
Publikováno v:
Antibodies, Vol 8, Iss 1, p 14 (2019)
Influenza B virus (IBV) circulates in the human population and causes considerable disease burden worldwide, each year. Current IBV vaccines can struggle to mount an effective cross-reactive immune response, as strains become mismatched, due to const
Externí odkaz:
https://doaj.org/article/2d937f77a1fe44b38a27029fbfd0875a
Autor:
Shanthi Jayawardena, Chung Y. Cheung, Ian Barr, Kwok H. Chan, Honglin Chen, Yi Guan, J.S. Malik Peiris, Leo L.M. Poon
Publikováno v:
Emerging Infectious Diseases, Vol 13, Iss 6, Pp 899-901 (2007)
We describe a 1-step reverse-transcription loop-mediated isothermal amplification assay for detection of highly pathogenic avian influenza A (H5N1) viruses. The assay was tested by using a panel of highly pathogenic H5N1 subtypes isolated over the pa
Externí odkaz:
https://doaj.org/article/5690eff7c61340598a6123a848784c35
Autor:
Junchao Jiang, Zhoude Zheng, Shengsong Chen, Jixiang Liu, Ju Jia, Yuhang Huang, Qing Liu, Chung Y. Cheung, Don D. Sin, Ting Yang, Chen Wang
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 14, p5512-5527, 16p
Autor:
Michael C. Chan, Suki M. Y. Lee, Chung Y. Cheung, Ka Pun Mok, Charmaine H. K. Wong, Yi Guan, Joseph S. M. Peiris, John M. Nicholls
Publikováno v:
The Journal of Infectious Diseases. 200:1104-1112
Human disease caused by highly pathogenic avian influenza (H5N1) is associated with fulminant viral pneumonia and mortality rates in excess of 60%. Cytokine dysregulation is thought to contribute to its pathogenesis. In comparison with human seasonal
Autor:
Chung Y. Cheung, Freek Cox, Els van Deventer, Edward Norbert van den Brink, Arjen Q. Bakker, Leo L.M. Poon, Jaap Goudsmit, Hans Wilhelm Doerr, Jan ter Meulen, Wilfred E. Marissen, Wolfgang Preiser, John de Kruif, Vincent T. K. Chow, Johannes A. Bogaards, Cynthia S. W. Leung, Joseph S. M. Peiris
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 3, Iss 7, p e237 (2006)
PLoS medicine, 3(7). Public Library of Science
PLoS Medicine, 3(7), 1071-1079. Public Library of Science
Ter Meulen, J, Van Den Brink, E N, Poon, L L M, Marissen, W E, Leung, C S W, Cox, F, Cheung, C Y, Bakker, A Q, Bogaards, J A, Van Deventer, E, Preiser, W, Doerr, H W, Chow, V T, De Kruif, J, Peiris, J S M & Goudsmit, J 2006, ' Human monoclonal antibody combination against SARS coronavirus : Synergy and coverage of escape mutants ', PLoS Medicine, vol. 3, no. 7, pp. 1071-1079 . https://doi.org/10.1371/journal.pmed.0030237
PLoS Medicine, Vol 3, Iss 7, p e237 (2006)
PLoS medicine, 3(7). Public Library of Science
PLoS Medicine, 3(7), 1071-1079. Public Library of Science
Ter Meulen, J, Van Den Brink, E N, Poon, L L M, Marissen, W E, Leung, C S W, Cox, F, Cheung, C Y, Bakker, A Q, Bogaards, J A, Van Deventer, E, Preiser, W, Doerr, H W, Chow, V T, De Kruif, J, Peiris, J S M & Goudsmit, J 2006, ' Human monoclonal antibody combination against SARS coronavirus : Synergy and coverage of escape mutants ', PLoS Medicine, vol. 3, no. 7, pp. 1071-1079 . https://doi.org/10.1371/journal.pmed.0030237
Background Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible. For an effective immune prophylaxis in humans, broad coverage of
Autor:
Yi Guan, Sin Fun Sia, Chung Y. Cheung, Kwok-Yung Yuen, Siamon Gordon, Mavis H.S. Wu, Iris H. Y. Ng, Winsie Luk, Joseph S. M. Peiris, Kwok-Hung Chan, Leo L.M. Poon
Publikováno v:
Journal of Virology
The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear. Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to compare the responses of human macrophages to infections with the SARS coronav
Autor:
Kwok H. Chan, Ian G. Barr, Leo L.M. Poon, J. S. Malik Peiris, Honglin Chen, Shanthi Jayawardena, Chung Y. Cheung, Yi Guan
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 13, Iss 6, Pp 899-901 (2007)
Emerging Infectious Diseases, Vol 13, Iss 6, Pp 899-901 (2007)
We describe a 1-step reverse-transcription loop-mediated isothermal amplification assay for detection of highly pathogenic avian influenza A (H5N1) viruses. The assay was tested by using a panel of highly pathogenic H5N1 subtypes isolated over the pa
Autor:
J. S. Malik Peiris, Martial Jaume, Ralf Altmeyer, François Kien, Isabelle Dutry, Roberto Bruzzone, Benoit Callendret, Chung Y. Cheung, HL Leung, Marc Daëron, Nicolas Escriou, Ming S. Yip, Ping H. Li, Béatrice Nal
Publikováno v:
Journal of Virology
Europe PubMed Central
Europe PubMed Central
Public health measures successfully contained outbreaks of the severe acute respiratory syndrome coronavirus (SARS-CoV) infection. However, the precursor of the SARS-CoV remains in its natural bat reservoir, and reemergence of a human-adapted SARS-li