Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chung S. Song"'
Publikováno v:
Cancer Research. 83:3070-3070
Advanced prostate cancer is a heterogeneous disease driven by diverse genetic alterations, with metastasis and lethal progression as the inevitable outcome. We observed that a subset of clinical primary prostate cancer is markedly reduced for SULT2B1
Autor:
Jodie Cropper, Sherry L. Werner, Bandana Chatterjee, Sulgi Park, Chung S. Song, Nooshin Mirkheshti, Shoulei Jiang
Publikováno v:
Oncotarget
Androgen receptor (AR) and PI3K/AKT/mTORC1 are major survival signals that drive prostate cancer to a lethal disease. Reciprocal activation of these oncogenic pathways from negative cross talks contributes to low/limited success of pathway-selective
Autor:
Yoon Tae Chung, Chung S. Song, Ibtissam Echchgadda, Young Kyo Seo, Bandana Chatterjee, Soyoung Kim
Publikováno v:
Gene. 386:218-223
The xenobiotic-activated nuclear receptors PXR (pregnane X receptor) and CAR (constitutive androstane receptor) and the vitamin D(3)-activated nuclear receptor VDR regulate steroid and xenobiotic metabolism by inducing the phase I cytochrome P450 mon
Autor:
Arun K. Roy, Baoyuan Bi, Chung S. Song, Bandana Chatterjee, Robert L. Vellanoweth, Yan Lavrovsky, Shuo Chen
Publikováno v:
Molecular Endocrinology. 12:1558-1566
Androgen receptor (AR) plays a key role in cell growth both in the normal prostate and in prostate cancer. Androgen ablation and prolonged antiandrogen therapy can give rise to AR-dependent prostate tumors, which nonetheless can grow in the androgen-
SULT2B1b Sulfotransferase: Induction by Vitamin D Receptor and Reduced Expression in Prostate Cancer
Autor:
Michael Ittmann, Chung S. Song, Barbara A. Christy, Rosario Mendez-Meza, Nooshin Mirkheshti, Soon Cheol Ahn, Sherry L. Abboud-Werner, Soyoung Kim, Young Kyo Seo, Bandana Chatterjee, Sherry G. Dodds
An elevated tumor tissue androgen level, which reactivates androgen receptor in recurrent prostate cancer, arises from the intratumor synthesis of 5α-dihydrotestosterone through use of the precursor steroid dehydroepiandrosterone (DHEA) and is fuele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99d28c954cfd404a648b5a181accbb7
https://europepmc.org/articles/PMC3656233/
https://europepmc.org/articles/PMC3656233/
Publikováno v:
Journal of Biological Chemistry. 270:837-842
Transcriptional regulation of the steroid hormone receptor genes plays a central role in temporal changes of target cell sensitivity during development, maturation, and aging. Sequence-specific DNA-protein interactions mediate these regulatory functi
Publikováno v:
Endocrinology. 131:1541-1546
Estrogen sulfotransferase (EST) catalyzes transfer of the sulfate group from phosphoadenosine phosphosulfate to estrogenic steroids. Since estrogen sulfates do not bind to the estrogen receptor with high affinity, EST can control the intracellular le
Autor:
Maria Slomczynska, Arun K. Roy, Chung S. Song, Tekmal R. Rao, W. F. Demyan, Song Her, Dong S. Kim, Bandana Chatterjee, Wolfgang Gallwitz
Publikováno v:
Molecular Endocrinology. 6:589-597
Mammalian estrogen sulfotransferase (EST; EC 2.8.2.4) sulfurylates the hydroxyl group of estrogenic steroids by transferring the sulfate from a cosubstrate adenosine 3'-phosphate-5'-phosphosulfate. Sulfurylated steroids do not bind to the estrogen re
Publikováno v:
Technical Tips Online. 2:42-44
Autor:
Liheng Shi, Bandana Chatterjee, Tae Sung Oh, Ibtissam Echchgadda, Chung S. Song, Young Kyo Seo, Sung A. Kim, So Young Kim, Sung Hwan Cho
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 20(4)
The vitamin D receptor (VDR) regulates steroid and drug metabolism by inducing the genes encoding phase I and phase II enzymes. SULT2A1 is a liver- and intestine-expressed sulfo-conjugating enzyme that converts the alcohol-OH of neutral steroids, bil