Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Chung Ming, Tse"'
Autor:
Mark Donowitz, Chung-Ming Tse, Rafiq Sarker, Ruxian Lin, Karol Dokladny, Manmeet Rawat, Ivy Horwitz, ChunYan Ye, George McNamara, Julie In, Alison Kell, Chenxu Guo, Shang JuiTsai, Tyrus Vong, Andrew Karaba, Varsha Singh, Jaiprasath Sachithanandham, Andy Pekosz, Andrea Cox, Steven Bradfute, Nicholas C. Zachos, Steven Gould, Olga Kovbasnjuk
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 5, Pp 101383- (2024)
Background & Aims: Diarrhea occurs in up to 50% of cases of COVID-19. Nonetheless, the pathophysiologic mechanism(s) have not been determined. Methods: This was examined using normal human enteroid monolayers exposed apically to live SARS-CoV-2 or no
Externí odkaz:
https://doaj.org/article/a260cf4d766d4c2ba6a4d40e688ad3df
Publikováno v:
Cellular Physiology and Biochemistry, Vol 56, Iss 1, Pp 39-49 (2022)
Externí odkaz:
https://doaj.org/article/d45cf81cb5bd40f1a590f9f90efa3f47
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Use of human enteroids studied in the undifferentiated and differentiated state that mimic the intestinal crypt and villus, respectively, has allowed studies of multiple enterocyte populations, including a large population of enterocytes that are tra
Externí odkaz:
https://doaj.org/article/539fdac05ebd4b8d81554b7fc200d074
Autor:
Byeongjun Lee, Gyu-Sang Hong, Sung Hoon Lee, Hyungsup Kim, Ajung Kim, Eun Mi Hwang, Jiyoon Kim, Min Goo Lee, Jin-Young Yang, Mi-Na Kweon, Chung-Ming Tse, Donowitz Mark, Uhtaek Oh
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 8, Pp 1-14 (2019)
Colitis: Intestinal membrane protein implicated in defective fluid secretion An ion channel, a membrane protein allowing ion transport, that controls the flow of chloride is needed for proper secretion of protective fluids in the intestine. Uhtaek Oh
Externí odkaz:
https://doaj.org/article/4e7c30ad99eb4d6397d3b848cfed433e
Autor:
Chung-Ming Tse, Jianyi Yin, Varsha Singh, Rafiquel Sarker, Ruxian Lin, Alan S. Verkman, Jerrold R. Turner, Mark Donowitz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 3, Pp 641-653 (2019)
Background & Aims: SLC26A3 (DRA) is an electroneutral Cl-/HCO3- exchanger that is present in the apical domain of multiple intestinal segments. An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3′,5
Externí odkaz:
https://doaj.org/article/565a8fd73e2844858353410d7094d254
Autor:
Jianyi Yin, Chung-Ming Tse, Leela Rani Avula, Varsha Singh, Jennifer Foulke-Abel, Hugo R. de Jonge, Mark Donowitz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 591-609 (2018)
Background & Aims: Human enteroids present a novel tool to study human intestinal ion transport physiology and pathophysiology. The present study describes the contributions of Cl- and HCO3- secretion to total cyclic adenosine monophosphate (cAMP)-st
Externí odkaz:
https://doaj.org/article/4f92a8c3a890408d92789264e3bdcf46
Publikováno v:
American Journal of Physiology-Cell Physiology.
In polarized intestinal epithelial cells, DRA is an apical Cl-/HCO3 - exchanger that is part of neutral NaCl absorption under baseline conditions but in cAMP driven diarrheas it is stimulated and contributes to increased anion secretion. To further u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dbdf505e5401fcbdce23c69f008949
https://doi.org/10.1152/ajpcell.00523.2022
https://doi.org/10.1152/ajpcell.00523.2022
Autor:
Wukun Liu, Sam Y. Hong, Zhaoli Sun, Brett R. Ullman, Jingxin Wang, Zlatina Tarmakova, Shridhar Bhat, Zufeng Guo, Ville O. Paavilainen, Manisha Das, Brandon J. Peiffer, Wei Li, Shahid Rehan, Imogen R. Coe, Cordelia Schiene-Fischer, Hanjing Peng, Gunter Fischer, Jun O. Liu, Chung Ming Tse
Publikováno v:
Nature chemistry
Rapamycin and FK506 are macrocyclic natural products with an extraordinary mode of action—they form binary complexes with FKBP through a shared FKBP-binding domain before forming ternary complexes with their respective targets, mTOR and calcineurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115b2634250a45b22adaa3931b6274f0
https://doi.org/10.32920/21979724
https://doi.org/10.32920/21979724
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 2, Pp 670-682 (2015)
Background: Vasopressin induced trafficking of aquaporin-2 (AQP2) containing vesicles has been studied in kidney cell lines using conventional fluorescent proteins as tags. However, trafficking of fluorescent tagged AQP2, which resembles the vectoria
Externí odkaz:
https://doaj.org/article/b712810bb4304a21aeefd9d0f2a89d65
Publikováno v:
American Journal of Physiology: Cell Physiology; Jun2023, Vol. 324 Issue 6, pC1263-C1273, 11p