Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Chung Ho Chang"'
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:791-795
Autor:
Wei-Syun Hu, Wei-Jen Ting, Wen-Dee Chiang, Peiying Pai, Yu-Lan Yeh, Chung-Ho Chang, Wan-Teng Lin, Chih-Yang Huang
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 10158-10172 (2015)
The prevalence of obesity is high in older adults. Alcalase potato protein hydrolysate (APPH), a nutraceutical food, might have greater benefits and be more economical than hypolipidemic drugs. In this study, serum lipid profiles and heart protective
Externí odkaz:
https://doaj.org/article/70e895534d284a65a5a037fa63712129
Autor:
Alexander Charng Dar Tsai, Chung Ho Chang, Jui Lin Wang, Chia-Lin Wu, Tao Hsiang Yang, Chia Chu Chang, Der Cherng Tarng
Publikováno v:
Clinical Science. 134:1593-1612
Transcriptional co-activator with PDZ-binding motif (TAZ) is a key downstream effector of the Hippo tumor-suppressor pathway. The functions of TAZ in the kidney, especially in tubular epithelial cells, are not well-known. To elucidate the adaptive ex
Autor:
Chung-Ho Chang, Jen-Ming Chen
Publikováno v:
Mathematical Problems in Engineering.
This paper presents a study on capacity policy for an OEM, launching a new short life cycle consumer durable product, and undergoes a demand diffusion process and a production ramp-up process with learning. The demand/supply dynamic system is describ
Autor:
Hui-Chin Wen, Chih-Pin Chuu, Chen-Yu Chen, Shine-Gwo Shiah, Hsing-Jien Kung, Kuang-Liang King, Liang-Chen Su, Shi-Chuan Chang, Chung-Ho Chang
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125518 (2015)
Nitric oxide (NO) is an essential signaling molecule in biological systems. Soluble guanylate cyclase (sGC), composing of α1 and β1 subunit, is the receptor for NO. Using radioimmunoassay, we discovered that activation of sGC by treatment with brad
Externí odkaz:
https://doaj.org/article/46b1f16a9c734c79a79154bfc7427322
Autor:
John M Kokontis, Hui-Ping Lin, Shih Sheng Jiang, Ching-Yu Lin, Junichi Fukuchi, Richard A Hiipakka, Chi-Jung Chung, Tzu-Min Chan, Shutsung Liao, Chung-Ho Chang, Chih-Pin Chuu
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109170 (2014)
The majority of prostate cancer (PCa) patient receiving androgen ablation therapy eventually develop castration-resistant prostate cancer (CRPC). We previously reported that androgen treatment suppresses Skp2 and c-Myc through androgen receptor (AR)
Externí odkaz:
https://doaj.org/article/630e19036e744c9a83ad7c2c060364e0
Autor:
Su-Jung Yang, Chen-Yu Chen, Geen-Dong Chang, Hui-Chin Wen, Ching-Yu Chen, Shi-Chuan Chang, Jyh-Fei Liao, Chung-Ho Chang
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58100 (2013)
Diabetes is characterized by chronic hyperglycemia, which in turn facilitates the formation of advanced glycation end products (AGEs). AGEs activate signaling proteins such as Src, Akt and ERK1/2. However, the mechanisms by which AGEs activate these
Externí odkaz:
https://doaj.org/article/3371b838bf234e1d996f0ede02c18ecf
Autor:
Chia Chu Chang, Hsi Chi Lu, Chih Yang Huang, Hui Chin Wen, Chung Ho Chang, Ming Shiu Hung, Chen Yu Chen, Woan Ling Chen
Publikováno v:
Obesity. 25:1932-1940
Objective Caveolin-1 (Cav-1) is expressed abundantly in adipose tissue and involved in many physiological processes. While Cav-1 has been reported to be secreted in pancreatic acinar cells and LNCaP prostate cancer cells, its secretion from adipose t
Autor:
Ching-Yu Lin, Hsu-Chen Cheng, Ting-Huan Chen, Horng-Dar Wang, Shih-Han Huang, Chih-Pin Chuu, Chih-Jen Lai, Chung-Ho Chang, Chi Jung Chung
Publikováno v:
The FASEB Journal. 31:5568-5576
Liver X receptors (LXRs) are important sensors and regulators for cholesterol, fatty acid, and glucose. LXRs play essential roles in the development and progression of cardiovascular diseases. We examined the effects of T0901317, a potent LXR agonist
Autor:
Chung Ho Chang, Ting Huan Chen, Hung Ming Wu, Hui Chin Wen, Cheng Chin Kuo, Chih Yang Huang, Geen-Dong Chang, Ching Hui Huang, Chen Yu Chen, Ping Fang Chiu, Chia Chu Chang, Chia-Lin Wu, Chew Teng Kor
Publikováno v:
Clinical Science. 131:1815-1829
Advanced glycation end-products (AGEs) form during oxidative stress, which is increased in diabetes mellitus (DM). Uromodulin is a protein with a renal protective effect, and may be subject to glycation. The implications of uromodulin glycation and A