Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chung Fang Lai"'
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148590 (2016)
Externí odkaz:
https://doaj.org/article/03f50ca18766453881216749fa5961e3
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143686 (2015)
Simvastatin (SIM) is anti-inflammatory. We used low density lipoprotein receptor knockout (LDLR-/-) mice and human aortic smooth muscle cells (HASMCs) as model systems to study the effect of SIM on arterial calcification and to explore the potential
Externí odkaz:
https://doaj.org/article/6f64e3d7f43d4643870132dc2c7c336a
Publikováno v:
Endocrinology. 153:3897-3910
In LDLR−/− mice fed high-fat diabetogenic diets, osteogenic gene-regulatory programs are ectopically activated in vascular myofibroblasts and smooth muscle cells that promote arteriosclerotic calcium deposition. Msx2-Wnt signaling pathways previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5603eeb9c3ace03c50de635d18298756
https://doi.org/10.1210/en.2012-1216
https://doi.org/10.1210/en.2012-1216
Autor:
Nicholas P. Ruthmann, Alan D. Waggoner, Joann L. Reagan, Chung Fang Lai, Victor G. Davila-Roman, Dwight A. Towler, Santhosh J. Mathews, Lisa de las Fuentes, C. Charles Gu
Publikováno v:
Journal of the American Society of Echocardiography. 21:954-960
Background Osteopontin (OPN)-transgenic mice exhibit increased carotid artery intima-media thickness (CIMT), smooth muscle cell proliferation, and atheroma formation. Methods An association of the human T-66G promoter variant with CIMT was examined i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acada669d1c13683f0c991135e5236a
https://doi.org/10.1016/j.echo.2008.02.005
https://doi.org/10.1016/j.echo.2008.02.005
Autor:
Jun Cai, Emily Huang, Su Li Cheng, Dwight A. Towler, Chung Fang Lai, Abraham Behrmann, Ziyad Al-Aly, Jian Su Shao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:2589-2596
Objective—Aortic calcification is prevalent in type II diabetes (T2DM), enhancing morbidity and tracking metabolic syndrome parameters.Ldlr−/−mice fed high-fat “Westernized” diets (HFD) accumulate aortic calcium primarily in the tunica medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb8825beda36c09d25115089a7826dd
https://doi.org/10.1161/atvbaha.107.153668
https://doi.org/10.1161/atvbaha.107.153668
Autor:
Abe Behrmann, Jun Cai, Jian Su Shao, Ziyad Al Aly, Chung Fang Lai, Dwight A. Towler, Su Li Cheng, Emily Huang
Publikováno v:
Annals of the New York Academy of Sciences. 1117:40-50
Studies of fracture repair have revealed that paracrine endothelial-mesenchymal interactions direct bone formation that restores osseous integrity. Angiogenic growth factors and specific members of the bone morphogenetic protein (BMP) family mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45225b3065f5321582fa3f14fed3fa50
https://doi.org/10.1196/annals.1402.075
https://doi.org/10.1196/annals.1402.075
Autor:
Kane Huang, Arwyn Schumacher, Jian Su Shao, Susan R. Rittling, David T. Denhardt, Chung Fang Lai, Radhika Vattikuti, Arleen P. Loewy, Jun Cai, Dwight A. Towler, Venkat Seshadri
Publikováno v:
Circulation Research. 98:1479-1489
Osteopontin (OPN) is a cytokine upregulated in diabetic vascular disease. To better understand its role in vascular remodeling, we assessed how OPN controls metalloproteinase (MMP) activation in aortic adventitial myofibroblasts (AMFs) and A7r5 vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba35512b88844bac3b53261500748dff
https://doi.org/10.1161/01.res.0000227550.00426.60
https://doi.org/10.1161/01.res.0000227550.00426.60
Publikováno v:
Journal of Bone and Mineral Research. 16:277-288
Numerous bone matrix proteins can interact with alpha(v)-containing integrins including alpha(v)beta3. To elucidate the net effects of the interaction between these proteins and alpha(v)beta3 on osteoblast function, we developed a murine osteoblastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66255908ccc4f46b687da05e3e08698b
https://doi.org/10.1359/jbmr.2001.16.2.277
https://doi.org/10.1359/jbmr.2001.16.2.277
Autor:
Roberto Civitelli, Meenakshi A. Chellaiah, Steven L. Teitelbaum, Louis V. Avioli, Kevin P. McHugh, Keith A. Hruska, F. Patrick Ross, Xu Feng, Aurora Fausto, Su-Li Cheng, Chung-Fang Lai
Publikováno v:
Journal of Cellular Biochemistry. 77:265-276
Long-term administration of pharmacological doses of glucocorticoids inhibits bone formation and results in osteoporosis. Since integrin-mediated cell-matrix interactions are essential for osteoblast function, we hypothesized that the detrimental eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc96c03be00c2920d1a987d0e0ad81cd
https://doi.org/10.1002/(sici)1097-4644(20000501)77:2<265::aid-jcb9>3.0.co
https://doi.org/10.1002/(sici)1097-4644(20000501)77:2<265::aid-jcb9>3.0.co
Autor:
Steven L. Teitelbaum, F. Patrick Ross, Chung-Fang Lai, Louis V. Avioli, Su-Li Cheng, Marisol E. Quiroz, Xu Feng
Publikováno v:
Journal of Biological Chemistry. 275:8331-8340
Murine osteoclast precursors and osteoblasts express the integrin alpha(v)beta(5), the appearance of which on the cell surface is controlled by the beta(5), and not the alpha(v), subunit. Here, we show that a 173-base pair proximal region of the beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e25ee2f1b161bfe5b28ce23426fe4b
https://doi.org/10.1074/jbc.275.12.8331
https://doi.org/10.1074/jbc.275.12.8331