Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chung Chen Su"'
Autor:
Ping-Tzu Chiu, Ming-Tain Lai, Ren-Yu Hsu, I-Ju Chen, Chun-Chung Wang, Yueh-Chin Wu, Wei-Chien Tang, Chi-Sheng Shia, Hui-Wen Chang, Hsin-Yi Tung, Chi-Huan Lu, Chung-Chen Su
Publikováno v:
Cancer Research. 81:955-955
Stage-specific embryonic antigen-4 (SSEA-4) ceramide, a globo-series hexasaccharide glycosphingolipid, has been reported to be a tumor-associated antigen. Here, we present a novel antibody-drug conjugate (ADC) targeting SSEA-4 to evaluate its potenti
Publikováno v:
Cancer Research. 81:3176-3176
Background/Aim: Globo-H (GH) and stage-specific embryonic antigen-4 (SSEA-4) are globo-series glycosphingolipid (GSL) antigens highly expressed on a variety of epithelial cancers. GH and SSEA-4 are reported to play an important role in cancer cell de
Autor:
Bei Chang Yang, Chung Chen Su, Yu Ping Lin, Yu Jung Cheng, Rudy L. Juliano, Huan Ching Lin, Jyun Yuan Huang
Publikováno v:
The Journal of Immunology. 185:1450-1459
Dense accumulations of T cells are often found in peritumoral areas, which reduce the efficiency of contact-dependent lysis of tumor cells. We demonstrate in this study that the extracellular matrix (ECM) produced by tumors can directly regulate T ce
Autor:
Huan Chin Lin, Yu Ping Lin, Chung Chen Su, Yu Jung Cheng, Bei Chang Yang, Ming Fei Liu, Jyun Yuan Huang
Publikováno v:
Molecular Immunology. 46:3328-3335
Delayed Fas-mediated apoptosis in T cells is associated with inflammatory diseases including rheumatoid arthritis (RA). CD3(+) T cells in RA synovia expressed high amounts of phospho-p38 MAPK. Exposure to RA synovial fluid or soluble collagen, a degr
Autor:
Chien Hsin Lee, Chung Chen Su, Jyun Yuan Huang, Wen Tsan Chang, Yu Ping Lin, Bei Chang Yang, Yu Jung Cheng
Publikováno v:
International Journal of Cancer. 123:1278-1285
Caspase-3 is known as a cysteine protease that primarily executes the cell death program. However, some tumors express higher levels of caspase-3 in positive correlation with malignancy. Here, we showed that caspase-3 can promote tumor metastasis in
Autor:
Chung Chen Su, Yu Jung Cheng, Jyun Yuan Huang, Bei Chang Yang, Yu Ping Lin, Yan Shen Shan, Woei Jer Chuang
Publikováno v:
The Journal of Immunology. 179:4589-4597
It has recently become apparent that the microenvironment made up of the extracellular matrix may affect cell signaling. In this study, we evaluated Fas-triggered apoptosis in T cells in contact with tumor cells, which resembles the cell-to-cell inte
Publikováno v:
Cellular immunology. 281(2)
T helper 17 (Th17) cells, which produce interleukin 17 (IL-17), are involved in the pathogenesis of autoimmune diseases and inflammatory conditions. Th17 cells have been detected in many Fas ligand-positive tumors. This study investigates the express
Autor:
Chung-Chen Su, 蘇重禎
97
Fas is a member of tumor necrosis factor (TNF) receptor family and mediates apoptosis when engagement with Fas ligand (FasL). It has been demonstrated that FasL expressed on tumor cells would crosslink with Fas protein of tumor-infiltrating l
Fas is a member of tumor necrosis factor (TNF) receptor family and mediates apoptosis when engagement with Fas ligand (FasL). It has been demonstrated that FasL expressed on tumor cells would crosslink with Fas protein of tumor-infiltrating l
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/80538237678494440391