Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Chunfang Gu"'
Autor:
Xingyao Li, Regan B. Kirkpatrick, Xiaodong Wang, Charles J. Tucker, Anuj Shukla, Henning J. Jessen, Huanchen Wang, Stephen B. Shears, Chunfang Gu
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114316- (2024)
Summary: Phosphate (Pi) serves countless metabolic pathways and is involved in macromolecule synthesis, energy storage, cellular signaling, and bone maintenance. Herein, we describe the coordination of Pi uptake and efflux pathways to maintain mammal
Externí odkaz:
https://doaj.org/article/f3b6e793e06f4a21a4aaa698b4a545cf
Autor:
Danye Qiu, Miranda S. Wilson, Verena B. Eisenbeis, Robert K. Harmel, Esther Riemer, Thomas M. Haas, Christopher Wittwer, Nikolaus Jork, Chunfang Gu, Stephen B. Shears, Gabriel Schaaf, Bernd Kammerer, Dorothea Fiedler, Adolfo Saiardi, Henning J. Jessen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitati
Externí odkaz:
https://doaj.org/article/a6c9f68025794db3aaf128b31c15130b
Autor:
Soumyadip Sahu, Jacob Gordon, Chunfang Gu, Mack Sobhany, Dorothea Fiedler, Robin E. Stanley, Stephen B. Shears
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 153 (2023)
Inositol pyrophosphates (PP-InsPs); are a functionally diverse family of eukaryotic molecules that deploy a highly-specialized array of phosphate groups as a combinatorial cell-signaling code. One reductive strategy to derive a molecular-level unders
Externí odkaz:
https://doaj.org/article/cdac5d5e38e7480aa0830c4af3bf7ffa
Autor:
Cun-Jin Zhang, Chenhui Wang, Meiling Jiang, Chunfang Gu, Jianxin Xiao, Xing Chen, Bradley N. Martin, Fangqiang Tang, Erin Yamamoto, Yibo Xian, Han Wang, Fengling Li, R. Balfour Sartor, Howard Smith, M. Elaine Husni, Fu-Dong Shi, Ji Gao, Julie Carman, Ashok Dongre, Susan C. McKarns, Ken Coppieters, Trine N. Jørgensen, Warren J. Leonard, Xiaoxia Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Adaptor for IL-17 receptors (Act1) is known to be crucial for IL-17-mediated immune responses. Here the authors show that Act1 also functions as a negative regulator of T and B cells by direct inhibition of STAT3.
Externí odkaz:
https://doaj.org/article/0e7548ce23cd448eb502abafb308eb2a
Autor:
Yanyu Wang, Sarah A Jenkins, Chunfang Gu, Ankita Shree, Margarita Martinez-Moczygemba, Jennifer Herold, Marina Botto, Rick A Wetsel, Yi Xu
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007579 (2019)
[This corrects the article DOI: 10.1371/journal.ppat.1005678.].
Externí odkaz:
https://doaj.org/article/0d71b0984a7f464680f0f269e18b7eb5
Autor:
Rizwan Yousaf, Chunfang Gu, Zubair M Ahmed, Shaheen N Khan, Thomas B Friedman, Sheikh Riazuddin, Stephen B Shears, Saima Riazuddin
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007297 (2018)
Autosomal recessive nonsyndromic hearing loss is a genetically heterogeneous disorder. Here, we report a severe-to-profound sensorineural hearing loss locus, DFNB100 on chromosome 5q13.2-q23.2. Exome enrichment followed by massive parallel sequencing
Externí odkaz:
https://doaj.org/article/82cbaa41f0b04304a24ab3821e971473
Autor:
Yanyu Wang, Sarah A Jenkins, Chunfang Gu, Ankita Shree, Margarita Martinez-Moczygemba, Jennifer Herold, Marina Botto, Rick A Wetsel, Yi Xu
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005968 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005678.].
Externí odkaz:
https://doaj.org/article/c256971a77bd49078c2ef3b9ae9ff379
Autor:
Yanyu Wang, Sarah A Jenkins, Chunfang Gu, Ankita Shree, Margarita Martinez-Moczygemba, Jennifer Herold, Marina Botto, Rick A Wetsel, Yi Xu
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005678 (2016)
Spores of Bacillus anthracis, the causative agent of anthrax, are known to persist in the host lungs for prolonged periods of time, however the underlying mechanism is poorly understood. In this study, we demonstrated that BclA, a major surface prote
Externí odkaz:
https://doaj.org/article/40555b242b6d42bdb8d76604a7c0de0e
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165286 (2016)
The HCT116 cell line, which has a pseudo-diploid karotype, is a popular model in the fields of cancer cell biology, intestinal immunity, and inflammation. In the current study, we describe two batches of diverged HCT116 cells, which we designate as H
Externí odkaz:
https://doaj.org/article/135259b3c4b649aba93ac2f4092dc70e
Autor:
Qiong Xue, Sarah A Jenkins, Chunfang Gu, Emanuel Smeds, Qing Liu, Ranga Vasan, Brooke H Russell, Yi Xu
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11665 (2010)
Dissemination of Bacillus anthracis from the respiratory mucosa is a critical step in the establishment of inhalational anthrax. Recent in vitro and in vivo studies indicated that this organism was able to penetrate the lung epithelium by directly en
Externí odkaz:
https://doaj.org/article/70ded28a401246d7b1cc5a5a303c7cc9