Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chunfa Qian"'
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19219- (2023)
Circular RNAs (circRNAs) are important non-coding RNAs (ncRNAs) involved in the development of multiple human diseases, especially cancers. circRNA_0084043 is significantly involved in the progression of melanoma. However, whether circRNA_0084043 is
Externí odkaz:
https://doaj.org/article/e940ebb00cdc4a18b36cfe3b17db37d2
Autor:
Yong Xiao, Zhen Wang, Mengjie Zhao, Wei Ji, Chong Xiang, Taiping Li, Ran Wang, Kun Yang, Chunfa Qian, Xianglong Tang, Hong Xiao, Yuanjie Zou, Hongyi Liu
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 9, Pp 9481-9504 (2022)
Background: Interferons (IFNs) have been implemented as anti-tumor immunity agents in clinical trials of glioma, but only a subset of glioblastoma (GBM) patients profits from it. The predictive role of IFNs stimulated genes in GBM needs further expl
Externí odkaz:
https://doaj.org/article/0f1ee4517080443c8d843d9e7affee1c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rechallenge of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) after PD-1 blockade failure was an effective therapy for non-small cell lung cancer (NSCLC) patients with resistance to EGFR-TKIs. The third-generation TKIs, like
Externí odkaz:
https://doaj.org/article/08057f4114444332a1236e334690e486
Autor:
Yong Xiao, Zhen Wang, Mengjie Zhao, Yanxiang Deng, Mingyu Yang, Graham Su, Kun Yang, Chunfa Qian, Xinhua Hu, Yong Liu, Liangyuan Geng, Yang Xiao, Yuanjie Zou, Xianglong Tang, Hongyi Liu, Hong Xiao, Rong Fan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human glioblastoma (GBM), the most aggressive brain tumor, comprises six major subtypes of malignant cells, giving rise to both inter-patient and intra-tumor heterogeneity. The interaction between different tumor subtypes and non-malignant cells to c
Externí odkaz:
https://doaj.org/article/1be535c10e8341ee88a744e8e0c98020
Autor:
Yongshuai Li, Lu Peng, Xianwen Cao, Kun Yang, Zhen Wang, Yong Xiao, Hong Xiao, Chunfa Qian, Hongyi Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
HOXC cluster antisense RNA 3 (HOXC-AS3) is a long noncoding RNA (lncRNA) that plays a crucial role in various tumors; nevertheless, its role in glioma and its mechanism have not been completely elucidated. In this research, we discovered that HOXC-AS
Externí odkaz:
https://doaj.org/article/b5e2b5981ffa4230ac25b2cdc21a2ff6
Autor:
Yong Xiao, Kun Yang, Zhen Wang, Mengjie Zhao, Yanxiang Deng, Wei Ji, Yuanjie Zou, Chunfa Qian, Yong Liu, Hong Xiao, Hongyi Liu
Publikováno v:
Frontiers in Surgery, Vol 8 (2022)
BackgroundGlioma is the most common primary brain tumor with a poor prognosis. Key genes that are negatively related to prognosis may provide the therapy targets to cure glioma. To clarify the role of CD44 in glioma, we explored its function at bulk-
Externí odkaz:
https://doaj.org/article/cf9263a0d50f40e9a27c1efe44828ee0
Publikováno v:
Anti-Cancer Drugs. 33:1182-1185
ALK rearrangement defines a unique non-small cell lung cancer (NSCLC) molecular subtype, of which the patients could potentially benefit from anti-ALK therapies. So far, the outcomes of the canonical EML-ALK patients subjected to ALK inhibitors are w
Publikováno v:
World Neurosurgery.
Autor:
Zhen Wang, Xianglong Tang, Mengjie Zhao, Yiding Zhang, Yong Xiao, Yuyang Liu, Chunfa Qian, Yandong Xie, Yong Liu, Yuanjie Zou, Kun Yang, Hongyi Liu
Background: Although RNA interference (RNAi) therapy has emerged as a potential tool in cancer therapeutics, the application of RNAi to glioblastoma (GBM) remains a hurdle. Herein, to improve the therapeutic effect of RNAi on GBM, a cancer cell membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93c3896fa3dafc5e18d768e46639c258
https://doi.org/10.21203/rs.3.rs-2512213/v1
https://doi.org/10.21203/rs.3.rs-2512213/v1
Publikováno v:
Journal of Cancer
Glioma is a pervasive malignancy and the main cause of cancer-related deaths worldwide. Circular RNA is an important subject of cancer research, and its role and function in glioma are poorly understood. This study demonstrated that hsa_circ_0091581