Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chuner Guo"'
Autor:
Chuner Guo, Wenjun Kong, Kenji Kamimoto, Guillermo C. Rivera-Gonzalez, Xue Yang, Yuhei Kirita, Samantha A. Morris
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract High-throughput single-cell assays increasingly require special consideration in experimental design, sample multiplexing, batch effect removal, and data interpretation. Here, we describe a lentiviral barcode-based multiplexing approach, Cel
Externí odkaz:
https://doaj.org/article/7d1b595046204728b15eb240cb6a3492
Autor:
Sarah E. Waye, Chuner Guo, Kenji Kamimoto, Samantha A. Morris, Wenjun Kong, Brent A. Biddy, Tao Sun
Publikováno v:
Nature
Direct lineage reprogramming involves the conversion of cellular identity. Single-cell technologies are useful for deconstructing the considerable heterogeneity that emerges during lineage conversion. However, lineage relationships are typically lost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f171c395031025aab063abff650fdbe
https://doi.org/10.1038/s41586-018-0744-4
https://doi.org/10.1038/s41586-018-0744-4
Autor:
Brent A. Biddy, Wenjun Kong, Kenji Kamimoto, Chuner Guo, Sarah Waye, Tao Sun, Samantha A Morris
Single-cell technologies are offering unprecedented insight into complex biology, revealing the behavior of rare cell populations that are typically masked in bulk population analyses. One current limitation of single-cell approaches is that lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ea1123d7f79cffc455f58a4276f246
https://doi.org/10.17504/protocols.io.yxifxke
https://doi.org/10.17504/protocols.io.yxifxke
Autor:
Chuner Guo, Wenjun Kong, Kamimoto, Kenji, Rivera-Gonzalez, Guillermo, Yang, Xue, Kirita, Yuhei, Morris, Samantha
Supplementary Figure S1 and S2 (PDF 18535 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db0dd7ffb8d0942731aa59b83de7d40
Autor:
Brent A. Biddy, Wenjun Kong, Kenji Kamimoto, Chuner Guo, Sarah Waye, Tao Sun, Samantha A Morris
Single-cell technologies are offering unprecedented insight into complex biology, revealing the behavior of rare cell populations that are typically masked in bulk population analyses. One current limitation of single-cell approaches is that lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90cf683c7ee27eec72e9b626a76bfb46
https://doi.org/10.17504/protocols.io.wfefbje
https://doi.org/10.17504/protocols.io.wfefbje
Autor:
Xuhua Chen, June He, Arnav Moudgil, Tomas Lagunas, Alexander J. Cammack, Michael N. Wilkinson, Michael J. Vasek, Samantha A. Morris, Zongtai Qi, Chuner Guo, Joseph D. Dougherty, Matthew A. Lalli, Robi D. Mitra
Publikováno v:
Cell
Cellular heterogeneity confounds in situ assays of transcription factor (TF) binding. Single-cell RNA sequencing (scRNA-seq) deconvolves cell types from gene expression, but no technology links cell identity to TF binding sites (TFBS) in those cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddcc8651d4a15a4cf41033c5e19fa21
https://doi.org/10.1016/j.cell.2020.06.037
https://doi.org/10.1016/j.cell.2020.06.037
Autor:
Samantha A Morris, Brent A. Biddy, Wenjun Kong, Kenji Kamimoto, Chuner Guo, Sarah Waye, Tao Sun
Single-cell technologies are offering unprecedented insight into complex biology, revealing the behavior of rare cell populations that are typically masked in bulk population analyses. One current limitation of single-cell approaches is that lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d4885984caeae1ef3155fb16bb2403
https://doi.org/10.17504/protocols.io.u9yez7w
https://doi.org/10.17504/protocols.io.u9yez7w
Autor:
Wenjun Kong, Chuner Guo, Xue Yang, Guillermo C. Rivera-Gonzalez, Kenji Kamimoto, Samantha A. Morris, Yuhei Kirita
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Genome Biology
Genome Biology
Single-cell technologies have seen rapid advancements in recent years, presenting new analytical challenges and opportunities. These high-throughput assays increasingly require special consideration in experimental design, sample multiplexing, batch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c3f1ccf01e6591bb3bd4ff8a40622b
https://doi.org/10.1101/335547
https://doi.org/10.1101/335547
Publikováno v:
Journal of Cellular and Molecular Medicine
Cardiomyocyte cell death is a major contributing factor to various cardiovascular diseases and is therefore an important target for the design of therapeutic strategies. More recently, stem cell therapies, such as transplantation of embryonic or indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848769b5e9e93b781c19a679e6d6ebd5
https://doi.org/10.1111/jcmm.12393
https://doi.org/10.1111/jcmm.12393
Publikováno v:
Current Gene Therapy. 13:133-138
Cardiac diseases are the major causes of morbidity and mortality in the world. Cardiomyocyte death is a common consequence of many types of heart diseases and is usually irreversible. Scar tissues formed by cardiac fibroblasts serve compensatory role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b8a5963067a17d509b23b9f6d191c0
https://doi.org/10.2174/1566523211313020007
https://doi.org/10.2174/1566523211313020007