Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Chunchun Zhi"'
1
Akademický článek
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9
Autor: Meng Cao, Yi Wang, Yijing Xiao, Dandan Zheng, Chunchun Zhi, Xin Xia, Xiaoqin Yuan
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Colorectal cancer (CRC) is a common tumor characterized by its high mortality. However, the underlying molecular mechanisms that drive CRC tumorigenesis are unclear. Clock genes have important roles in tumor development. In the pr
Externí odkaz: https://doaj.org/article/3bf7d80775694354a25287f893fbf1e7
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2
Akademický článek
Clinical significance of PD-L1 expression in serum-derived exosomes in NSCLC patients
Autor: Chuling Li, Chuwei Li, Chunchun Zhi, Wenjun Liang, Xuan Wang, Xi Chen, Tangfeng Lv, Qin Shen, Yong Song, Dang Lin, Hongbing Liu
Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Exosomes are 50–150 nm endocytic vesicles secreted by almost all type of cells that carry bioactive molecules from host. These small vesicles are considered to be novel cross-talk circuits established by tumor cells and tumor mi
Externí odkaz: https://doaj.org/article/99f5aefad13d4bbab19acb607e332f6e
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3
Akademický článek
1,25(OH)2D3 deficiency-induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model
Autor: Wenjing Zhu, Jiayao Yan, Chunchun Zhi, Qianwen Zhou, Xiaoqin Yuan
Publikováno v: Gut Pathogens, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background The relationship between disturbances of the gut microbiota and 1,25(OH)2D3 deficiency has been established both in humans and animal models with a vitamin D poor diet or a lack of sun exposure. Our prior study has demonstrated th
Externí odkaz: https://doaj.org/article/f42fabac3ebe4d999a84f85688f8d6f4
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4
Akademický článek
1,25(OH)2D3 Deficiency Induces Colon Inflammation via Secretion of Senescence-Associated Inflammatory Cytokines.
Autor: Yun Liu, Lulu Chen, Chunchun Zhi, Ming Shen, Weiwei Sun, Dengshun Miao, Xiaoqin Yuan
Publikováno v: PLoS ONE, Vol 11, Iss 1, p e0146426 (2016)
Epidemiological studies showed that 1,25-Dihydroxyvitamin D[1,25(OH)2D3] insufficiency appears to be associated with aging and colon cancer while underlying biological mechanisms remain largely unknown. Inflammatory bowel disease is one of the risk f
Externí odkaz: https://doaj.org/article/d332ad9a9dbe48418d5bb40c70287da2
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5
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9
Autor: Xin Xia, Xiaoqin Yuan, Yi Wang, Chunchun Zhi, Yijing Xiao, Dandan Zheng, Meng Cao
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Background Colorectal cancer (CRC) is a common tumor characterized by its high mortality. However, the underlying molecular mechanisms that drive CRC tumorigenesis are unclear. Clock genes have important roles in tumor development. In the present stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b255515abee05b423fab06d0d07f8c
https://doi.org/10.1186/s13046-021-01936-4
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6
RANBP1 promotes colorectal cancer progression by regulating pre-miRNA nuclear export via a positive feedback loop with YAP
Autor: Dandan, Zheng, Meng, Cao, Siyu, Zuo, Xin, Xia, Chunchun, Zhi, Yanbing, Lin, Sitong, Deng, Xiaoqin, Yuan
Publikováno v: Oncogene. 41(7)
Colorectal cancer (CRC) is among the top five most common malignant tumors worldwide and has a high mortality rate. Identification of the mechanism of CRC and potential therapeutic targets is critical for improving survival. In the present study, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e7ef8cadaf9f4325623ab29908cc09f
https://pubmed.ncbi.nlm.nih.gov/34983930
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9
Clinical significance of PD-L1 expression in serum-derived exosomes in NSCLC patients
Autor: Wenjun Liang, Tangfeng Lv, Xuan Wang, Chuwei Li, Chuling Li, Dang Lin, Qin Shen, Hongbing Liu, Xi Chen, Chunchun Zhi, Yong Song
Publikováno v: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Journal of Translational Medicine
Background Exosomes are 50–150 nm endocytic vesicles secreted by almost all type of cells that carry bioactive molecules from host. These small vesicles are considered to be novel cross-talk circuits established by tumor cells and tumor microenviro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0841c56c89f470e6a486da4783c2c58
https://doi.org/10.1186/s12967-019-2101-2
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