Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chunan Cheng"'
Publikováno v:
PeerJ, Vol 12, p e17229 (2024)
Background Current drugs for treating osteoporosis may lead to toxic side effects. Echinacoside (ECH) is a natural small molecule drug. This study examined and compared the therapeutic effects of cross-linker (CL)-ECH and ECH-free nanoparticles on os
Externí odkaz:
https://doaj.org/article/f2d7a8b8d5644107b34010881809c0dc
Autor:
Yuanye Tian, Qi Shao, Jiahong Gu, Yi Tang, Miaomiao Bie, Yangyifan Zhou, Chunan Cheng, Yi Liang, Qian Zhang, Feiwu Kang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Osteoclasts, which are multinucleated cells formed by monocyte fusion, play a key role in bone resorption. Hypoxia-inducible factor (HIF)-1α is vital for the development of osteoclasts in hypoxic environments and during bone resorption.
Externí odkaz:
https://doaj.org/article/1e3b4afb54aa48da92f3c45b1d053cea
Publikováno v:
Journal of Biomedical Nanotechnology. 18:2599-2611
Drug delivery by innovative nanoparticles into osteogenesis-associated cells has excellent potential for periodontitis therapy. However, a deep understanding of how the nanoparticles boost the bioactivity of delivered drugs is lacking. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7474ebda041d2e9b5770fd9aa897ce5e
https://doi.org/10.1166/jbn.2022.3468
https://doi.org/10.1166/jbn.2022.3468
Autor:
Miaomiao, Bie, Yi, Tang, Yuxing, Xia, Qian, Zhang, Yuanye, Tian, Chunan, Cheng, Xinzhao, Li, Xin, Qi, Feiwu, Kang
Publikováno v:
SSRN Electronic Journal.
Osteoporosis induced by disuse because of bed rest or the aerospace industry has become one of the most common skeletal disorders. However, mechanisms underlying the disuse osteoporosis remain largely unknown. We validated the tail-suspended model in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b46e7c2dce4800d8cb0c5450810937f
https://doi.org/10.2139/ssrn.4263596
https://doi.org/10.2139/ssrn.4263596