Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Chunai Gong"'
Autor:
Juanjuan Li, Chunai Gong, Xinlu Chen, Huanhuan Guo, Zongguang Tai, Nan Ding, Shen Gao, Yuan Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Doxorubicin (Dox) has been recommended in clinical guidelines for the standard-of-care treatment of breast cancer. However, Dox therapy faces challenges such as hypoxia, acidosis, H2O2-rich conditions and condensed extracellular m
Externí odkaz:
https://doaj.org/article/f87fcfae78264fbe824bcec4c34d0bfb
Autor:
Jiyuan Chen, Yujie Wang, Lu Han, Rong Wang, Chunai Gong, Gang Yang, Zhe Li, Shen Gao, Yongfang Yuan
Publikováno v:
Materials Today Bio, Vol 17, Iss , Pp 100484- (2022)
Second-generation androgen receptor (AR) inhibitors such as enzalutamide are the first-line treatments for castration-resistant prostate cancer (CRPC). Resistance to enzalutamide will greatly increase the difficulty of prostate cancer treatment and r
Externí odkaz:
https://doaj.org/article/0a3d2516dca24e6abc88d642ced5ee42
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract In addition to early detection, early diagnosis, and early surgery, it is of great significance to use new strategies for the treatment of hepatocellular carcinoma (HCC). Studies showed that the combination of sorafenib (SFN) and triptolide
Externí odkaz:
https://doaj.org/article/1d25b4879e14403eb8ab6ea156d3f244
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Abstract Background Biomimetic nanotechnology-based RNA interference (RNAi) has been successful in improving theranostic efficacy in malignant tumors. Its integration with hybrid biomimetic membranes made of natural cell membranes fused with liposoma
Externí odkaz:
https://doaj.org/article/c3d1d78b798448d2aaca207a3331f012
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds great promise for effective suppression of tumor growth and invasion. In this study, a pH-responsive co-delivery platform was developed for metformin (Met
Externí odkaz:
https://doaj.org/article/9eb12f984cc34b76bc375e05f64355fa
Autor:
Zhimin Han, Chunai Gong, Juanjuan Li, Huanhuan Guo, Xinlu Chen, Yangli Jin, Shen Gao, Zongguang Tai
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100170- (2022)
Immune checkpoint blockade has been proven to have great therapeutic potential and has revolutionized the treatment of tumors. However, various limitations remain, including the low response rate of exhausted T cells and mutual regulation of multiple
Externí odkaz:
https://doaj.org/article/f89ecf3f17e74e31bf7c192ba8c8faed
Autor:
Chunai Gong, Xiaoyan Yu, Benming You, Yan Wu, Rong Wang, Lu Han, Yujie Wang, Shen Gao, Yongfang Yuan
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various
Externí odkaz:
https://doaj.org/article/878d51497f4b43ee9106f21c0ea4738c
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Enzalutamide (Enz) has shown limited bioavailability via oral administration. Castration-resistant prostate cancer (CRPC) is frequent among patients receiving 18–24 months of androgen deprivation therapy. The nonsteroidal anti-a
Externí odkaz:
https://doaj.org/article/889e03307e3b416587c831df2efe369b
Autor:
Chunai Gong, Jing Tian, Zhuo Wang, Yuan Gao, Xin Wu, Xueying Ding, Lei Qiang, Guorui Li, Zhimin Han, Yongfang Yuan, Shen Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-18 (2019)
Abstract Exosomes (Exo) hold great promise as endogenous nanocarriers that can deliver biological information between cells. However, Exo are limited in terms of their abilities to target specific recipient cell types. We developed a strategy to isol
Externí odkaz:
https://doaj.org/article/de1e87f3c57a457a8f8bd6d6cde628c3
Autor:
Lei Qiang, Zheng Cai, Wenjun Jiang, Jiyong Liu, Zongguang Tai, Guorui Li, Chunai Gong, Shen Gao, Yuan Gao
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tumor site remain the ma
Externí odkaz:
https://doaj.org/article/231d8489219d4f2f976e274907e1df4b