Zobrazeno 1 - 10
of 84
pro vyhledávání: '"ChunMei Jin"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1459 (2024)
Objective: To establish and validate an LC-MS/MS method for the simultaneous determination of curcumin (CUR) as well as its glucuronide conjugate (COG) and sulfate conjugate (COS) in rat plasma. The method was employed to evaluate and compare the pha
Externí odkaz:
https://doaj.org/article/37dee1962a6346c2aed67538f5b262af
Publikováno v:
Molecules, Vol 29, Iss 21, p 5024 (2024)
Toxoplasmosis, a zoonotic infection caused by Toxoplasma gondii (T. gondii), poses a significant risk to human health and public safety. Despite the availability of clinical treatments, none effectively mitigate the intestinal barrier damage, which i
Externí odkaz:
https://doaj.org/article/21ac88b434fe4ed68221f43bd85eb6bf
Autor:
Jinle Lou, Nan Li, Xue Jiang, Xu Cai, Lingchao Wang, Xia Wu, Wenpeng Zhang, Chunmei Jin, Xiaomei Zhuang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1140 (2024)
As a novel guanylate cyclase stimulator, SGC003F is being developed for the treatment of heart failure with a reduced ejection fraction (HFrEF). This study aimed to assess the effect of P-glycoprotein (P-gp) inhibition on SGC003F exposure in vivo, co
Externí odkaz:
https://doaj.org/article/622bc75714a74540ae40eaaf3a34df27
Autor:
Muwon Kang, Yinhua Zhang, Hyae Rim Kang, Seoyeong Kim, Ruiying Ma, Seungjoon Lee, Yunho Yi, Chunmei Jin, Dongmin Lee, Eunjoon Kim, Kihoon Han
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S588- (2023)
Externí odkaz:
https://doaj.org/article/f11f3a7958ca4da193691b5d03372ec9
Autor:
Yoonhee Kim, Tae Hee Ko, Chunmei Jin, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Huiling Li, Jong-Il Choi, Kihoon Han
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Shank3 is a member of the Shank family proteins (Shank1–3), which are abundantly present in the postsynaptic density (PSD) of neuronal excitatory synapses. As a core scaffold in the PSD, Shank3 plays a critical role in organizing the macromolecular
Externí odkaz:
https://doaj.org/article/4809dd1322b645638fa70cb197674b80
Autor:
Chunmei Jin, Yeunkum Lee, Hyojin Kang, Kwon Jeong, Joori Park, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Hyunyoung Seong, Yoonhee Kim, Hosung Jung, Jin Young Kim, Yoon Ki Kim, Kihoon Han
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders. Although the fun
Externí odkaz:
https://doaj.org/article/a5d01e752d3f48ab8b849fd86580ad31
Autor:
Gyu Hyun Kim, Yinhua Zhang, Hyae Rim Kang, Seung-Hyun Lee, Jiwon Shin, Chan Hee Lee, Hyojin Kang, Ruiying Ma, Chunmei Jin, Yoonhee Kim, Su Yeon Kim, Seok-Kyu Kwon, Se-Young Choi, Kea Joo Lee, Kihoon Han
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-5 (2020)
Abstract Variants of the cytoplasmic FMR1-interacting protein (CYFIP) gene family, CYFIP1 and CYFIP2, are associated with numerous neurodevelopmental and neuropsychiatric disorders. According to several studies, CYFIP1 regulates the development and f
Externí odkaz:
https://doaj.org/article/fde856e6f3674168aade04b64efb45ca
Publikováno v:
Animal Cells and Systems, Vol 23, Iss 4, Pp 270-274 (2019)
Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for nor
Externí odkaz:
https://doaj.org/article/2e6637bfcc70436e8050c10be6c41860
Autor:
Chunmei Jin, Hyojin Kang, Taesun Yoo, Jae Ryun Ryu, Ye-Eun Yoo, Ruiying Ma, Yinhua Zhang, Hyae Rim Kang, Yoonhee Kim, Hyunyoung Seong, Geul Bang, Sangwoo Park, Seok-Kyu Kwon, Woong Sun, Hyunkyung Kim, Jin Young Kim, Eunjoon Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Variants of the SH3 and multiple ankyrin repeat domains 3 (SHANK3), which encodes postsynaptic scaffolds, are associated with brain disorders. The targeted alleles in a few Shank3 knock-out (KO) lines contain a neomycin resistance (Neo) cassette, whi
Externí odkaz:
https://doaj.org/article/3b0f76fae5d0442a8ae3a8d14537d7bc
Autor:
Yinhua Zhang, Rim Kang Hyae, Seung-Hyun Lee, Yoonhee Kim, Ruiying Ma, Chunmei Jin, Ji-Eun Lim, Seoyeon Kim, Yeju Kang, Hyojin Kang, Su Yeon Kim, Seok-Kyu Kwon, Se-Young Choi, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its critical role in proper neuronal development and function. CY
Externí odkaz:
https://doaj.org/article/ac0c71e09bd841429a58affb1fdfb6bd