Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Chun-yu Deng"'
Autor:
Qing-Rui Wu, Hui Yang, Hui-Dan Zhang, Yong-Jiang Cai, Yan-Xiang Zheng, Heng Fang, Zi-Fan Wang, Su-Juan Kuang, Fang Rao, Huan-Lei Huang, Chun-Yu Deng, Chun-Bo Chen
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Pyroptosis plays a crucial role in sepsis, and the abnormal handling of myocyte calcium (Ca2+) has been associated with cardiomyocyte pyroptosis. Specifically, the inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is a Ca2+ release channe
Externí odkaz:
https://doaj.org/article/d16c13dc467b4792bdef3654675c5912
Autor:
Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li, Su-Juan Kuang, Ying-Yu Lai, Fang Rao, Yu-Mei Xue, Ji-Jin Lin, Shuang-Xin Liu, Chun-Bo Chen, Chun-Yu Deng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract Mitochondrial dysfunction and impaired Ca2+ handling are involved in the development of diabetic cardiomyopathy (DCM). Dynamic relative protein 1 (Drp1) regulates mitochondrial fission by changing its level of phosphorylation, and the Orai1
Externí odkaz:
https://doaj.org/article/9539d6068d28411a80554bb61795b308
Autor:
Yuan Fang, Qian Li, Xin Li, Guan-Hao Luo, Su-Juan Kuang, Xue-Shan Luo, Qiao-Qiao Li, Hui Yang, Yang Liu, Chun-Yu Deng, Yu-Mei Xue, Shu-Lin Wu, Fang Rao
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypertension is a major cardiovascular risk factor for atrial fibrillation (AF) worldwide. However, the role of mechanical stress caused by hypertension on downregulating the L-type calcium current (ICa,L), which is vital for AF occurrence, remains u
Externí odkaz:
https://doaj.org/article/579946f9d698430bb355a0dae7d2b4e3
Autor:
Qiaoqiao Li, Yingyu Lai, Xiaoyan Gao, Xin Li, Chun-Yu Deng, Huiming Guo, Junfei Zhao, Hui Yang, Yuwen Xu, Shulin Wu, Yumei Xue, Fang Rao
Publikováno v:
PeerJ, Vol 9, p e11488 (2021)
Atrial fibrillation is the most common form of cardiac arrhythmia. Atrial fibrosis is a significant feature of atrial fibrillation though its mechanism is not well understood. We searched the Gene Expression Omnibus database to compare mRNA expressio
Externí odkaz:
https://doaj.org/article/2f1e6df3fc9849dca47dc5089fee229f
Autor:
Qiaoqiao Li, Shenghong Lei, Xueshan Luo, Jintao He, Yuan Fang, Hui Yang, Yang Liu, Chun-Yu Deng, Shulin Wu, Yu-Mei Xue, Fang Rao
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 23, Iss 7, p 247 (2022)
Background: Valvular heart disease (VHD) is a major precipitating factor of atrial fibrillation (AF) that contributes to decreased cardiac function, heart failure, and stroke. Stroke induced by VHD combined with atrial fibrillation (AF-VHD) is a much
Externí odkaz:
https://doaj.org/article/af84ca009ab2489d88b67aedfa7743f4
Autor:
He-Ping Lei, Min Qin, Li-Yun Cai, Hong Wu, Lan Tang, Ju-E Liu, Chun-Yu Deng, Yi-Bin Liu, Qian Zhu, Han-Ping Li, Wei Hu, Min Yang, Yi-Zhun Zhu, Shi-Long Zhong
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
It is widely accepted that genetic polymorphisms impact atorvastatin (ATV) metabolism, clinical efficacy, and adverse events. The objectives of this study were to identify novel genetic variants influencing ATV metabolism and outcomes in Chinese pati
Externí odkaz:
https://doaj.org/article/92983670d3ce4691bb2cfc11418a814f
Autor:
Chun-Yu Deng, Hui Yang, Su-Juan Kuang, Fang Rao, Yu-Mei Xue, Zhi-Ling Zhou, Xiao-Ying Liu, Zhi-Xin Shan, Xiao-Hong Li, Qiu-Xiong Lin, Shu-Lin Wu, Xi-Yong Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107128 (2014)
5-Hydroxytryptamine (5-HT) is a powerful constrictor of coronary arteries and is considered to be involved in the pathophysiological mechanisms of coronary-artery spasm. However, the mechanism of enhancement of coronary-artery constriction to 5-HT du
Externí odkaz:
https://doaj.org/article/ddeab7088e074ab284867aeed93e00d0
Autor:
Jie-Ning Zhu, Ren Chen, Yong-Heng Fu, Qiu-Xiong Lin, Shuai Huang, Lin-Lin Guo, Meng-Zhen Zhang, Chun-Yu Deng, Xiao Zou, Shi-Long Zhong, Min Yang, Jian Zhuang, Xi-Yong Yu, Zhi-Xin Shan
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75557 (2013)
Carvedilol, a nonselective β-adrenoreceptor antagonist, protects against myocardial injury induced by acute myocardium infarction (AMI). The mechanisms underlying the anti-fibrotic effects of carvedilol are unknown. Recent studies have revealed the
Externí odkaz:
https://doaj.org/article/4b96c3b8713c4e52be87e650dfbd44d7
Autor:
Xiao-Hui Xu, Hai-Ying Sun, Yan-Hui Zhang, Wei Wu, Kui-Hao Chen, Yi Liu, Chun-Yu Deng, Xi-Yong Yu, Man-Wen Jin, Gui-Rong Li
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51550 (2012)
Allitridi (diallyl trisulfide) is an active compound (volatile oil) from garlic. The previous studies reported that allitridi had anti-arrhythmic effect. The potential ionic mechanisms are, however, not understood. The present study was designed to d
Externí odkaz:
https://doaj.org/article/94ec8f6e397949cebf22472c9268831f
Autor:
Qian Li, Yuan Fang, De-wei Peng, Lu-an Li, Chun-yu Deng, Hui Yang, Su-juan Kuang, Qiao-qiao Li, Meng-zhen Zhang, Peng Zeng, Qian-huan Zhang, Yang Liu, Hai Deng, Wei Wei, Yu-mei Xue, Shu-lin Wu, Fang Rao
Publikováno v:
European Journal of Pharmacology. 952:175754