Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chun-qi Zhu"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 116992- (2024)
The effective treatment of acute lung injury (ALI) remains a significant challenge. Patients with ALI demonstrate an abundance of proinflammatory mediators in both bronchoalveolar lavage fluid (BALF) and circulating plasma. Bardoxolone methyl (BM) is
Externí odkaz:
https://doaj.org/article/10ac805cf8cf41fd96043c2aeb25b35a
Autor:
Alexandra Vargas, Oliver Simon, Matthias Kittelmann, Melissa M. Lin, Chun-qi Zhu, Hongmei Li, Su-Er W. Huskey, Helen Gu, Sarah Favara, Handan He, Jin Zhang, Ry R. Forseth, Lai Wang, Alexandre Luneau, Heidi J. Einolf, Fabian K. Eggimann, James B. Mangold
Publikováno v:
Drug Metabolism and Disposition. 44:653-664
KAE609 [(1'R,3'S)-5,7'-dichloro-6'-fluoro-3'-methyl-2',3',4',9'-tetrahydrospiro[indoline-3,1'-pyridol[3,4-b]indol]-2-one] is a potent, fast-acting, schizonticidal agent being developed for the treatment of malaria. After oral dosing of KAE609 to rats
Publikováno v:
ISCA