Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chun-po S Fan"'
Machine learning approaches to the human metabolome in sepsis identify metabolic links with survival
Autor:
Leah B. Kosyakovsky, Emily Somerset, Angela J. Rogers, Michael Sklar, Jared R. Mayers, Augustin Toma, Yishay Szekely, Sabri Soussi, Bo Wang, Chun-Po S. Fan, Rebecca M. Baron, Patrick R. Lawler
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background Metabolic predictors and potential mediators of survival in sepsis have been incompletely characterized. We examined whether machine learning (ML) tools applied to the human plasma metabolome could consistently identify and priori
Externí odkaz:
https://doaj.org/article/1869f77095d14faeb8a4d192627ea5db
Autor:
Tisiana Low, Brian W. McCrindle, Brigitte Mueller, Chun-Po S. Fan, Emily Somerset, Sunita O’Shea, Leonard J. S. Tsuji, Hong Chen, Cedric Manlhiot
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The etiology of Kawasaki Disease (KD), the most common cause of acquired heart disease in children in developed countries, remains elusive, but could be multifactorial in nature as suggested by the numerous environmental and infectious expos
Externí odkaz:
https://doaj.org/article/08b61f0f751a4dcea68f1ea6d82ae41f
Autor:
Dakota Gustafson, Michelle Ngai, Ruilin Wu, Huayun Hou, Alice Carvalhal Schoffel, Clara Erice, Serena Mandla, Filio Billia, Michael D. Wilson, Milica Radisic, Eddy Fan, Uriel Trahtemberg, Andrew Baker, Chris McIntosh, Chun-Po S. Fan, Claudia C. dos Santos, Kevin C. Kain, Kate Hanneman, Paaladinesh Thavendiranathan, Jason E. Fish, Kathryn L. Howe
Publikováno v:
EBioMedicine, Vol 78, Iss , Pp 103982- (2022)
Summary: Background: Endothelial cell (EC) activation, endotheliitis, vascular permeability, and thrombosis have been observed in patients with severe coronavirus disease 2019 (COVID-19), indicating that the vasculature is affected during the acute s
Externí odkaz:
https://doaj.org/article/46e3fc0616f94c3a9b413970ac0543e2
Autor:
Fernando L. Scolari, Sagi Abelson, Darshan H. Brahmbhatt, Jessie J.F. Medeiros, Chun‐Po S. Fan, Nicole L. Fung, Vesna Mihajlovic, Markus S. Anker, Madison Otsuki, Patrick R. Lawler, Heather J. Ross, Adriana C. Luk, Stefan Anker, John E. Dick, Filio Billia
Publikováno v:
European Journal of Heart Failure. 24:1573-1582
Cardiogenic shock (CS) with variable systemic inflammation may be responsible for patient heterogeneity and the exceedingly high mortality rate. Cardiovascular events have been associated with clonal haematopoiesis (CH) where specific gene mutations
Autor:
Yasbanoo Moayedi, Eduard Rodenas-Alesina, Brigitte Mueller, Chun-Po S. Fan, Wida S. Cherikh, Josef Stehlik, Jeffrey J. Teuteberg, Heather J. Ross, Kiran K. Khush
Publikováno v:
Circulation: Heart Failure. 16
Background: In Europe, there is greater acceptance of hearts from higher-risk donors for transplantation, whereas in North America, the donor heart discard rate is significantly higher. A Donor Utilization Score (DUS) was used to compare European and
Autor:
Devin Chetan, Adrienn B. Szabo, Chun-Po S. Fan, Conall T. Morgan, Olivier Villemain, Rajiv R. Chaturvedi, Lee N. Benson, Osami Honjo
Publikováno v:
The Annals of thoracic surgery.
Compare outcomes of Melody valve to mechanical mitral valve replacement (MVR) for young children.Children who underwent Melody MVR from 2014-2020 were case-matched to mechanical MVR patients. Transplant-free survival and cumulative incidence of re-in
Autor:
Natasha Aleksova, Chun‐Po S. Fan, Farid Foroutan, Yas Moayedi, Juan Duero Posada, Caroline McGuinty, Adriana Luk, Josef Stehlik, Heather J. Ross, Ana C. Alba
Publikováno v:
Clinical Transplantation. 36
Predicted heart mass (PHM) was neither derived nor evaluated in an obese population. Our objective was to evaluate size mismatch using actual body weight or ideal body weight (IBW)-adjusted PHM on mortality and risk assessment.We conducted a retrospe
Autor:
Alejandro A Floh, Shubhadeep Das, Maruti Haranal, Peter C Laussen, Lynn Crawford-Lean, Chun-Po S Fan, Luc L Mertens, Kyle Runeckles, Osami Honjo
Publikováno v:
Perfusion.
Background Del Nido cardioplegia (DNc) was designed for superior myocardial protection during cardiopulmonary bypass (CPB). We conducted a retrospective review to explore if DNc was associated with increase in systemic ventricle dysfunction (sVD) fol
Autor:
Bhavikkumar Langanecha, sajith kesavan, Mike Seed, Steven M Schwartz, Osami Honjo, Chun-po S Fan, Jennifer Russell, Paula Pereira-Solomos, jennifer thomas, Andreea Dragulescu, Katherine Taylor, Alejandro Floh
Publikováno v:
Circulation. 144
Introduction: Unplanned intervention before stage 2 palliation (S2P) in patients with single ventricle (SV) lesions with dual unobstructed outflows palliated with pulmonary artery banding (PAB) is common. The factors contributing to intervention and
Autor:
Minh B Nguyen, Andreea Dragulescu, Rajiv Chaturvedi, Chun-po S Fan, olivier villemain, Mark K Friedberg, Luc L Mertens
Publikováno v:
Circulation. 144
Introduction: Diagnosing diastolic dysfunction (DD) non-invasively in children is challenging as no validated pediatric diagnostic algorithm is available. The aim of this study is to use machine learning (ML) to identify a model that integrates echoc