Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Chun-li Zhang"'
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110706- (2024)
Summary: Microglia, as the immune cells of the central nervous system (CNS), play dynamic roles in both healthy and diseased conditions. The ability to genetically target microglia using viruses is crucial for understanding their functions and advanc
Externí odkaz:
https://doaj.org/article/8cab44a6dcae4a309abb7cbb7c3c35f4
Autor:
Meng-Lu Liu, Shuaipeng Ma, Wenjiao Tai, Xiaoling Zhong, Haoqi Ni, Yuhua Zou, Jingcheng Wang, Chun-Li Zhang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Effective therapeutics is much needed for amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease mainly affecting motor neurons. By screening chemical compounds in human patient-derived and aging-relevant motor neurons
Externí odkaz:
https://doaj.org/article/8de14841118a4091a8c6c8aac7b2349e
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108895- (2024)
Summary: Spinal cord injury (SCI) often leads to neuronal loss, axonal degeneration, and behavioral dysfunction. We recently show that in vivo reprogramming of NG2 glia produces new neurons, reduces glial scaring, and ultimately leads to improved fun
Externí odkaz:
https://doaj.org/article/0dfd754ed5b84394bd44fe5c1d04018d
Autor:
Shuaipeng Ma, Chun-Li Zhang
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 8, Pp 1639-1640 (2024)
Externí odkaz:
https://doaj.org/article/1fe09030aeb044b4890c5d338399e6ed
Autor:
Ru Feng, Shuai Zhang, Jiang-Tao Li, Ting Wang, Chun-Li Zhang, Jie-Fei Bai, Lei Yang, Li-Ru Wang, Hong-Mei Jing, Hui Liu
Publikováno v:
Therapeutic Advances in Hematology, Vol 14 (2023)
Background: The outcome of patients with acute myeloid leukemia (AML) aged ⩾65 years is poor. Effective treatment options are limited for patients with AML who cannot tolerate intensive chemotherapy. Objectives: We aimed to evaluate the efficacy of
Externí odkaz:
https://doaj.org/article/771f334bc48d48ecbd77ff8a87fd84d5
Autor:
Chao-qiong Jin, Jing Zhao, Xiao-yun Ding, Liang-liang Yu, Guo-liang Ye, Xin-jian Zhu, Jian-wei Shen, Ye Yang, Bo Jin, Chun-li Zhang, Bin Lv
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundEndoscopic submucosal dissection (ESD) for early gastric cancer (EGC) does not always lead to curative resection. Risk factors of lymph node metastasis (LNM)/local cancer residue after non-curative ESD for EGC have not been fully elucidated
Externí odkaz:
https://doaj.org/article/cbe17d3fbda943969387ce5555d2e531
Publikováno v:
International Journal of Ophthalmology, Vol 15, Iss 8, Pp 1391-1400 (2022)
Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and medical constraints, many children receive treatment only in the metaphase and advanced clinical stages, resulting in high rates of blindness and disability. Althou
Externí odkaz:
https://doaj.org/article/cd1555220a194a1789b6f4ea00f377f0
Autor:
Chih-Wei Zeng, Chun-Li Zhang
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/2871a3ad4d83422281f94380d1f63ddc
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104531- (2023)
Summary: Background: Reprogramming resident glial cells to convert them into neurons in vivo represents a potential therapeutic strategy that could replenish lost neurons, repair damaged neural circuits, and restore function. AAV (adeno-associated vi
Externí odkaz:
https://doaj.org/article/c009cc05f8af4cc3904131b86882a384
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Alzheimer’s disease (AD) is an adult-onset mental disorder with aging as a major risk factor. Early and progressive degeneration of basal forebrain cholinergic neurons (BFCNs) contributes substantially to cognitive impairments o
Externí odkaz:
https://doaj.org/article/a5c276bc190a4cebb63bd43ff52bf1f8