Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chun-ge Zhang"'
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Grey mold disease results from Botrytis cinerea, a classical “high-risk” plant pathogenic fungus in meaning of resistance development to fungicides, and its management depends largely on the frequent applications of fungicides. The evolution of r
Autor:
Shu-di Yang, Ben-gang You, Xue-nong Zhang, Ji-zhao Li, Chun-ge Zhang, Chun Liu, Zhi-qiang Yuan, Wen-jing Zhu, Wei-liang Chen, Xiao-feng Zhou, Yang Liu
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:2093-2106
P-glycoprotein (P-gp) plays an importantrole in multidrug resistance (MDR), proved to be one of the major obstacles in cancer chemotherapy. Cationic polymers could specifically deliver siRNA to tumor cells and thus reverse MDR by the downregulation o
Autor:
Wei-liang Chen, Ji-zhao Li, Wen-jing Zhu, Yang Liu, Zhi-qiang Yuan, Shu-di Yang, Xue-nong Zhang, Chun Liu, Xiao-feng Zhou, Chun-ge Zhang
Publikováno v:
International Journal of Pharmaceutics. 492:141-151
This study aimed to prepare efficient cRGDyK peptide-decorated micelles for the targeted therapy of non-small-cell lung cancer (NSCLC). An amphiphilic copolymer N-succinyl-palmitoyl-chitosan (SPCS) was synthesized and characterized. cRGDyK peptide is
Autor:
Yi Zhou, Xue-nong Zhang, Shu-di Yang, Wei-liang Chen, Yang Liu, Qiao-Ling Zhu, Min Guan, Zhi-qiang Yuan, Aijun Zhu, Xiao-feng Zhou, Chun-ge Zhang, Chun Liu
Publikováno v:
Biomaterials. 35:5965-5976
Developing safe and effective carriers of small interference RNA (siRNA) is a significant demand for the systemic delivery of siRNA. In this study, low-density lipoprotein (LDL) was isolated from human plasma and loaded with cholesterol-conjugated si
Autor:
Yong Jin, Zhang Xuenong, Wei-liang Chen, Qiao-Ling Zhu, Shu-di Yang, Kai-Peng Wang, Zhi-qiang Yuan, Xiao-feng Zhou, Chun-ge Zhang, Yang Liu, Ben-gang You
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 4:235-244
Autor:
Xiao-feng Zhou, Yang Liu, Chun Liu, Wei-liang Chen, Xue-nong Zhang, Chun-ge Zhang, Ji-zhao Li, Shu-di Yang, Wen-jing Zhu, Zhi-qiang Yuan
Publikováno v:
Scientific Reports
Co-delivery of chemotherapeutics and siRNA with different mechanisms in a single system is a promising strategy for effective cancer therapy with synergistic effects. In this study, a triblock copolymer micelle was prepared based on the polymer of N-
Autor:
Chun-Ge, Zhang, Shu-di, Yang, Wen-Jing, Zhu, Ben-Gang, You, Yang, Liu, Zhi-Qiang, Yuan, Wei-Liang, Chen, Ji-Zhao, Li, Xiao-Feng, Zhou, Chun, Liu, Xue-Nong, Zhang
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 105(7)
P-glycoprotein (P-gp) plays an importantrole in multidrug resistance (MDR), proved to be one of the major obstacles in cancer chemotherapy. Cationic polymers could specifically deliver siRNA to tumor cells and thus reverse MDR by the downregulation o
Autor:
Wei-liang Chen, Chun-ge Zhang, Wen-jing Zhu, Zhi-qiang Yuan, Ben-gang You, Shu-di Yang, Rong Zhu, Xue-nong Zhang, Xiao-feng Zhou, Yang Liu, Ji-zhao Li
Publikováno v:
Scientific Reports
An antibody that specifically interacts with an antigen could be applied to an active targeting delivery system. In this study, CD147 antibody was coupled with α-hed chitosan nanoparticles (α-Hed-CS-NPs). α-Hed-CS-CD147-NPs were round and spherica
Autor:
Yong Jin, Peng Xia, Yong-Yan Bei, Xue-nong Zhang, Qiao-Ling Zhu, Yang Liu, Xiao-Juan Hu, Chun-ge Zhang, Xiao-feng Zhou, Wei-liang Chen, Ben-gang You, Liang Zhang, Zhi-qiang Yuan
Publikováno v:
Expert opinion on drug delivery. 11(6)
Polymeric micelles is a safe and effective delivery system, which belong to the targeted delivery system (TDS). An anticancer drug, harmine(HM) is a hydrophobic drug with much adverse effects when used for treatment of liver cancer. Chitosan (CS) is
Application of the central composite design to optimize the preparation of novel micelles of harmine
Autor:
Xiao-Juan Hu, Xue-nong Zhang, Yong Jin, Qiao-Ling Zhu, Yang Liu, Peng Xia, Yong-Yan Bei, Xiao-feng Zhou, Wei-liang Chen, Zhi-qiang Yuan, Liang Zhang, Chun-ge Zhang, Ben-gang You
Publikováno v:
International Journal of Nanomedicine
Yong-Yan Bei,1,* Xiao-Feng Zhou,2,3,* Ben-Gang You,1 Zhi-Qiang Yuan,1 Wei-Liang Chen,1 Peng Xia,1 Yang Liu,1 Yong Jin,4 Xiao-Juan Hu,1 Qiao-Ling Zhu,1 Chun-Ge Zhang,1 Xue-Nong Zhang,1 Liang Zhang5 1Department of Pharmaceutics, College of Pharmaceutic