Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Chun-Yuh Huang"'
Autor:
Xiaomin Cai, Christopher Warburton, Olivia F. Perez, Ying Wang, Lucy Ho, Christina Finelli, Quinn T. Ehlen, Chenzhou Wu, Carlos D. Rodriguez, Lee Kaplan, Thomas M. Best, Chun-Yuh Huang, Zhipeng Meng
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109983- (2024)
Summary: Recent studies have implicated a crucial role of Hippo signaling in cell fate determination by biomechanical signals. Here we show that mechanical loading triggers the activation of a Hippo-PKCζ-NFκB pathway in chondrocytes, resulting in t
Externí odkaz:
https://doaj.org/article/a5d261a63306466bb3727e2c0bbac1f2
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 110 (2024)
In this review, we discuss the interaction of mechanical factors influencing knee osteoarthritis (KOA) and post-traumatic osteoarthritis (PTOA) pathogenesis. Emphasizing the importance of mechanotransduction within inflammatory responses, we discuss
Externí odkaz:
https://doaj.org/article/cad4b7c6e946430ba9510083822b311b
Autor:
James M, Lai, Veshesh, Patel, Arjun, Watane, Aaron J, Fils, Parastou, Pakravan, Chun-Yuh, Huang, Nimesh, Patel, Jayanth, Sridhar, Nicolas A, Yannuzzi
Publikováno v:
Ophthalmology Retina. 6:1001-1008
To investigate the mechanical properties of 23-, 25-, and 27-gauge vitrectomy vitrectors across 3 different vitrectomy systems to inform surgical techniques.An experimental study that did not involve any human subjects.Nine vitrectors (3 each of 23-,
Autor:
Logan A, Beatty, Kailey L, Mansour, Evan J, Bryant, Franklin, Garcia-Godoy, Domingo, Santos Pantaleon, Yoh, Sawatari, Chun-Yuh, Huang
Publikováno v:
Stem Cells and Development. 31:498-505
Paracrine factors secreted in the conditioned media (CMs) of periodontal ligament-derived stem cells (PDLSCs) have been shown to downregulate inflammatory effects of interleukin (IL)-1β on chondrocytes wherein milk fat globule-epidermal growth facto
Publikováno v:
Stem cells and development. 31(15-16)
Publikováno v:
Computers in Biology and Medicine. :107039
Publikováno v:
Stem cells and development. 31(15-16)
Chondrogenesis is the process of differentiation of stem cells into mature chondrocytes. Such a process consists of chemical, functional, and structural changes which are initiated and mediated by the host environment of the cells. To date, the mecha
Publikováno v:
Journal of biomechanics. 128
Early therapeutic intervention to mitigate inflammatory responses following joint injury may offer a potential strategy to prevent post-traumatic osteoarthritis (PTOA). In-vitro studies have demonstrated uniaxial dynamic compression mitigates the cat
Autor:
Xue Yin, Yoh Sawatari, Franklin Garcia-Godoy, Oraya Vesvoranan, Chun Yuh Huang, Amanda Montoya, Valeria Londono
Publikováno v:
Stem cells and development. 30(10)
Osteoarthritis (OA) is the most common type of arthritis, afflicting millions of people in the world. Elevation of inflammatory mediators and enzymatic matrix destruction is often associated with OA. Therefore, the objective of this study was to inve
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
As the most common cause of low back pain, the cascade of intervertebral disc (IVD) degeneration is initiated by the disappearance of notochordal cells and progressive loss of proteoglycan (PG). Limited nutrient supply in the avascular disc environme