Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chun-Yue I. Lee"'
Autor:
Keith W. Ward, Chun-Yue I. Lee, Sarabjit S Gahir, Mitsumasa Sakamoto, Scott A. Reisman, Joel W. Proksch
Publikováno v:
Drug Design, Development and Therapy. 13:1259-1270
Background Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates genes with antioxidative, anti-inflammatory, and mitochondrial bioenergetic properties, and is being eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c218317af4d50940f3be3d79f04b58
https://doi.org/10.2147/dddt.s193889
https://doi.org/10.2147/dddt.s193889
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 34
Omaveloxolone is a potent activator of Nrf2, a master transcriptional regulator of a multitude of cytoprotective functions, including antioxidative, anti-inflammatory, and mitochondrial bioenergetic effects. Some of the most potent known effects of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0a9f1824f2f595a1b634a87a57272e
https://doi.org/10.1002/jbt.22526
https://doi.org/10.1002/jbt.22526
Autor:
Scott A, Reisman, Sarabjit S, Gahir, Chun-Yue I, Lee, Joel W, Proksch, Mitsumasa, Sakamoto, Keith W, Ward
Publikováno v:
Drug Design, Development and Therapy
Background Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates genes with antioxidative, anti-inflammatory, and mitochondrial bioenergetic properties, and is being eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f45cee680b7bd7f75d3159099274880
https://pubmed.ncbi.nlm.nih.gov/31118567
https://pubmed.ncbi.nlm.nih.gov/31118567
Publikováno v:
Archives of Dermatological Research. 306:447-454
RTA 408 is a member of the synthetic oleanane triterpenoid class of compounds known to potently activate the cytoprotective transcription factor Nrf2. Because skin is constantly exposed to external oxidative stress, such as that from ultraviolet radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c326b6e29eb0a1b4f064db54c1cee138
https://doi.org/10.1007/s00403-013-1433-7
https://doi.org/10.1007/s00403-013-1433-7
Publikováno v:
The Journal of Immunology. 200:175.22-175.22
RTA 1701 is an orally-bioavailable, selective RORγt inhibitor. RORγt orchestrates the differentiation of Th17 cells and contributes to autoimmune disease pathogenesis. Inhibition of RORγt suppresses Th17 cells and the associated secretion of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc3d2f96ae3bc05b6c96f933a94edb8
https://doi.org/10.4049/jimmunol.200.supp.175.22
https://doi.org/10.4049/jimmunol.200.supp.175.22
Autor:
Koli Taghizadeh, Line M. Nordstrand, Sureshkumar Muthupalani, Arne Klungland, Chun-Yue I. Lee, Catherine A. Moroski-Erkul, Leona D. Samson, Lisiane B. Meira, Lindsey W. Eichinger, Jennifer A. Calvo, Nona Abolhassani
Publikováno v:
The Journal of clinical investigation. 122(7)
More than 15% of cancer deaths worldwide are associated with underlying infections or inflammatory conditions, therefore understanding how inflammation contributes to cancer etiology is important for both cancer prevention and treatment. Inflamed tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab630e9fa60b5e1e28956a4040f8365e
https://pubmed.ncbi.nlm.nih.gov/22684101
https://pubmed.ncbi.nlm.nih.gov/22684101
Autor:
Ayelet Maor-Shoshani, Maria Kartalou, Chun-Yue I. Lee, John M. Essigmann, Leona D. Samson, Gondichatnahalli M. Lingaraju, James C. Delaney
Publikováno v:
PubMed Central
The human 3-methyladenine DNA glycosylase (AAG) recognizes and excises a broad range of purines damaged by alkylation and oxidative damage, including 3-methyladenine, 7-methylguanine, hypoxanthine (Hx), and 1,N[superscript 6]-ethenoadenine (εA). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b200a2a9ad55b3ad88ec66e86156d4e
https://pubmed.ncbi.nlm.nih.gov/19219989
https://pubmed.ncbi.nlm.nih.gov/19219989