Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Chun-Yu Deng"'
Autor:
Qing-Rui Wu, Hui Yang, Hui-Dan Zhang, Yong-Jiang Cai, Yan-Xiang Zheng, Heng Fang, Zi-Fan Wang, Su-Juan Kuang, Fang Rao, Huan-Lei Huang, Chun-Yu Deng, Chun-Bo Chen
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Pyroptosis plays a crucial role in sepsis, and the abnormal handling of myocyte calcium (Ca2+) has been associated with cardiomyocyte pyroptosis. Specifically, the inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is a Ca2+ release channe
Externí odkaz:
https://doaj.org/article/d16c13dc467b4792bdef3654675c5912
Autor:
Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li, Su-Juan Kuang, Ying-Yu Lai, Fang Rao, Yu-Mei Xue, Ji-Jin Lin, Shuang-Xin Liu, Chun-Bo Chen, Chun-Yu Deng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract Mitochondrial dysfunction and impaired Ca2+ handling are involved in the development of diabetic cardiomyopathy (DCM). Dynamic relative protein 1 (Drp1) regulates mitochondrial fission by changing its level of phosphorylation, and the Orai1
Externí odkaz:
https://doaj.org/article/9539d6068d28411a80554bb61795b308
Autor:
Yuan Fang, Qian Li, Xin Li, Guan-Hao Luo, Su-Juan Kuang, Xue-Shan Luo, Qiao-Qiao Li, Hui Yang, Yang Liu, Chun-Yu Deng, Yu-Mei Xue, Shu-Lin Wu, Fang Rao
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypertension is a major cardiovascular risk factor for atrial fibrillation (AF) worldwide. However, the role of mechanical stress caused by hypertension on downregulating the L-type calcium current (ICa,L), which is vital for AF occurrence, remains u
Externí odkaz:
https://doaj.org/article/579946f9d698430bb355a0dae7d2b4e3
Autor:
Qiaoqiao Li, Yingyu Lai, Xiaoyan Gao, Xin Li, Chun-Yu Deng, Huiming Guo, Junfei Zhao, Hui Yang, Yuwen Xu, Shulin Wu, Yumei Xue, Fang Rao
Publikováno v:
PeerJ, Vol 9, p e11488 (2021)
Atrial fibrillation is the most common form of cardiac arrhythmia. Atrial fibrosis is a significant feature of atrial fibrillation though its mechanism is not well understood. We searched the Gene Expression Omnibus database to compare mRNA expressio
Externí odkaz:
https://doaj.org/article/2f1e6df3fc9849dca47dc5089fee229f
Autor:
Qiaoqiao Li, Shenghong Lei, Xueshan Luo, Jintao He, Yuan Fang, Hui Yang, Yang Liu, Chun-Yu Deng, Shulin Wu, Yu-Mei Xue, Fang Rao
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 23, Iss 7, p 247 (2022)
Background: Valvular heart disease (VHD) is a major precipitating factor of atrial fibrillation (AF) that contributes to decreased cardiac function, heart failure, and stroke. Stroke induced by VHD combined with atrial fibrillation (AF-VHD) is a much
Externí odkaz:
https://doaj.org/article/af84ca009ab2489d88b67aedfa7743f4
Autor:
He-Ping Lei, Min Qin, Li-Yun Cai, Hong Wu, Lan Tang, Ju-E Liu, Chun-Yu Deng, Yi-Bin Liu, Qian Zhu, Han-Ping Li, Wei Hu, Min Yang, Yi-Zhun Zhu, Shi-Long Zhong
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
It is widely accepted that genetic polymorphisms impact atorvastatin (ATV) metabolism, clinical efficacy, and adverse events. The objectives of this study were to identify novel genetic variants influencing ATV metabolism and outcomes in Chinese pati
Externí odkaz:
https://doaj.org/article/92983670d3ce4691bb2cfc11418a814f
Autor:
Qian Li, Yuan Fang, De-wei Peng, Lu-an Li, Chun-yu Deng, Hui Yang, Su-juan Kuang, Qiao-qiao Li, Meng-zhen Zhang, Peng Zeng, Qian-huan Zhang, Yang Liu, Hai Deng, Wei Wei, Yu-mei Xue, Shu-lin Wu, Fang Rao
Publikováno v:
European Journal of Pharmacology. 952:175754
Autor:
Xiao‐Yan Gao, Ying‐Yu Lai, Xue‐Shan Luo, De‐Wei Peng, Qiao‐Qiao Li, Hui‐Shan Zhou, Yu‐Mei Xue, Hui‐Ming Guo, Jun‐Fei Zhao, Hui Yang, Su‐Juan Kuang, Zhao‐Yu Wang, Meng‐Zhen Zhang, Chun‐Yu Deng, Shu‐Lin Wu, Fang Rao
Publikováno v:
Aging Cell. 22
Atrial fibrosis induced by aging is one of the main causes of atrial fibrillation (AF), but the potential molecular mechanism is not clear. Acetyltransferase p300 participates in the cellular senescence and fibrosis, which might be involved in the ag
Autor:
Chun-Yu Deng, Zhiming Ye, Xia Chen, Caoshuai Dou, Yingzhen Wen, Zhiwen Lian, Wenjian Wang, Juan Hu, Sijia Li, Wei Shi, Zhuo Li, Ruizhao Li, Guibao Ke, Qianmei Zhang, Jianchao Ma, Ruyi Liao, Xueqin Chen, Lixia Xu, Ting Lin, Wei Dong, Li Zhang, Yue Du, Houqin Xiao, Yuanhan Chen, Bohou Li, Fengxia Zhang, Chaosheng He, Zhonglin Feng, Shuangshuang Zhu, Shuangxin Liu, Jie Xiao, Xingchen Zhao, Minghao Zheng, Xinling Liang, Su-Juan Kuang, Hong Zhang
Publikováno v:
Kidney International. 100:377-390
Receptor activator of NF-κB (RANK) expression is increased in podocytes of patients with diabetic nephropathy. However, the relevance of RANK to diabetic nephropathy pathobiology remains unclear. Here, to evaluate the role of podocyte RANK in the de
Autor:
Dan‐Lin Zheng, Qing‐Rui Wu, Peng Zeng, Sui‐Min Li, Yong‐Jiang Cai, Shu‐Zhen Chen, Xue‐Shan Luo, Su‐Juan Kuang, Fang Rao, Ying‐Yu Lai, Meng‐Yuan Zhou, Fei‐Long Wu, Hui Yang, Chun‐Yu Deng
Publikováno v:
Aging cellREFERENCES. 21(12)
Diabetes mellitus (DM) is a common chronic metabolic disease caused by significant accumulation of advanced glycation end products (AGEs). Atrial fibrillation (AF) is a common cardiovascular complication of DM. Here, we aim to clarify the role and me