Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chun-Mien Chang"'
Autor:
Ronak Lakhia, Harini Ramalingam, Chun-Mien Chang, Patricia Cobo-Stark, Laurence Biggers, Andrea Flaten, Jesus Alvarez, Tania Valencia, Darren P. Wallace, Edmund C. Lee, Vishal Patel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
ADPKD, a common aetiology of kidney failure, is caused by heterozygous PKD1 or PKD2 mutations. Here the authors show that preventing 3′-UTR cis-inhibition of mRNAs produced by the non-inactivated PKD1/2 alleles ameliorates preclinical ADPKD.
Externí odkaz:
https://doaj.org/article/5c3d27a136564233923d3e2f24e558f2
Autor:
Chun-Mien Chang, Amaka M. Awanye, Leanne Marsay, Christina Dold, Andrew J. Pollard, Christine S. Rollier, Ian M. Feavers, Martin C.J. Maiden, Jeremy P. Derrick
Publikováno v:
Derrick, J 2022, ' Application of a Neisseria meningitidis antigen microarray to identify candidate vaccine proteins from a human Phase I clinical trial ', Vaccine, vol. 40, no. 28, pp. 3835-3842 . https://doi.org/10.1016/j.vaccine.2022.05.032
Meningococcal meningitis is a rare but serious condition affecting mainly children and young adults. Outer membrane vesicles (OMV) from Neisseria meningitidis have been used successfully as vaccines against the disease, although they only provide pro
Autor:
Mien-Chie Hung, Cheng-Wen Wu, Jin-Shing Chen, Long-Yuan Li, Zhenbo Han, Chien-Hua Chen, Shu-Pei Lien, Chun-Mien Chang, Shih-Jen Liu, Yuh-Pyng Sher
Supplementary Figure 2 from Cancer-Targeted BikDD Gene Therapy Elicits Protective Antitumor Immunity against Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff980227bd84b4abd70ed152b61a34d
https://doi.org/10.1158/1535-7163.22502044.v1
https://doi.org/10.1158/1535-7163.22502044.v1
Autor:
Mien-Chie Hung, Cheng-Wen Wu, Jin-Shing Chen, Long-Yuan Li, Zhenbo Han, Chien-Hua Chen, Shu-Pei Lien, Chun-Mien Chang, Shih-Jen Liu, Yuh-Pyng Sher
Supplementary Figure 1 from Cancer-Targeted BikDD Gene Therapy Elicits Protective Antitumor Immunity against Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1ee1ba60e0b39fb49833361c515697
https://doi.org/10.1158/1535-7163.22502047.v1
https://doi.org/10.1158/1535-7163.22502047.v1
Autor:
Elizabeth Hernandez, Sophia Le, Tina Nguyen, Yuzhou Liu, Jer Tsong Hsieh, Payal Kapur, Chun Mien Chang, Yu-An Chen, Keith P. Johnston, Xiaowei Dong
Publikováno v:
Journal of Biomedical Nanotechnology. 16:583-593
Metronomic chemotherapy, giving low doses of chemotherapeutics (e.g., docetaxel) on a frequent schedule over a long time, may improve outcomes and reduce side effects for cancer patients. Oral medications are vital for applying metronomic chemotherap
Autor:
Chun-mien Chang, 張君銘
95
Ag473, a vaccine candidate for the protection against Neisseria meningitidis infection, is a highly conserved lipoprotein of unknown function and predicted to form an extremely high degree of α-helical structure. The specific aims of this st
Ag473, a vaccine candidate for the protection against Neisseria meningitidis infection, is a highly conserved lipoprotein of unknown function and predicted to form an extremely high degree of α-helical structure. The specific aims of this st
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/50258971501858333003
Autor:
Harini, Ramalingam, Sonu, Kashyap, Patricia, Cobo-Stark, Andrea, Flaten, Chun-Mien, Chang, Sachin, Hajarnis, Kyaw Zaw, Hein, Jorgo, Lika, Gina M, Warner, Jair M, Espindola-Netto, Ashwani, Kumar, Mohammed, Kanchwala, Chao, Xing, Eduardo N, Chini, Vishal, Patel
Publikováno v:
Cell metabolism. 33(6)
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disorder marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that catalyzes the abundant N
Autor:
Chun Mien Chang, Wei Chun Chang, Pei Yin Liao, Yu Ting Su, Wen Lung Ma, Long Bin Jeng, Wei Min Chung, Chun Chieh Yeh, Hsueh Chou Lai
Publikováno v:
Anticancer research. 40(3)
Background/aim The role of androgen receptor (AR) in hepatocellular carcinoma (HCC) development is controversial. Therefore, the translational value of targeting AR in HCC is unknown. Sorafenib, a multiple kinase inhibitor, is the standard therapy fo
Autor:
Sonu Kashyap, Chao Xing, Patricia Cobo-Stark, Jorgo Lika, Sachin Hajarnis, Harini Ramalingam, Kyaw Zaw Hein, Gina M. Warner, Mohammed Kanchwala, Eduardo N. Chini, Ashwani Kumar, Vishal Patel, Jair Machado Espindola-Netto, Chun Mien Chang, Andrea Flaten
Publikováno v:
Cell Metabolism. 33:1234-1247.e7
Summary Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disorder marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that catalyzes the abundant N6-methyladenosine (m6A) RNA modification, is
Autor:
Hongwei Zhao, Carlos M. Roggero, Junhang Luo, Ming Wang, Rui Tao Wang, Elizabeth Hernandez, Chun Mien Chang, Zhi Ping Liu, Jason Gao, Qing Jun Zhang, Josep Rizo, Yanping Liang, Kai Jiang Yu, Jian Lu, Guanghua Xiao, Rey Chen Pong, Yong Fang, Jun Lu, Jung-Mo Ahn, David T. Hoang, Jer Tsong Hsieh, Payal Kapur, Jiazheng Cao, Zhenhua Chen, Andrew Dang, Lingling Duan
Publikováno v:
Nucleic Acids Research
Alternative splicing is emerging as an oncogenic mechanism. In prostate cancer, generation of constitutively active forms of androgen receptor (AR) variants including AR-V7 plays an important role in progression of castration-resistant prostate cance