Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Chun-Lin Zhang"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Direct synthesis of ketones from aldehydes features high atom- and step-economy. Yet, the coupling of aldehydes with unactivated alkyl C(sp3)-H remains challenging. Herein, we develop the synthesis of ketones from aldehydes via alkyl C(sp3)-
Externí odkaz:
https://doaj.org/article/73c235715e1443d98479be2ee8050293
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Three-component carboacylation of simple alkenes often requires directing groups and strained substrates. Here, the authors report a photoredox N-heteroyclic carbene/Pd-catalysed alkylacylation of alkenes with aldehydes and unactivated alkyl halides;
Externí odkaz:
https://doaj.org/article/658ff6d2402748ff9d9e5ecdb4a50a1c
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Ischemic stroke is a highly complex systemic disease characterized by intricate interactions between the brain and gastrointestinal tract. While our current understanding of these interactions primarily stems from experimental models, their relevance
Externí odkaz:
https://doaj.org/article/dc0bf7d9f2ea4ec9ab464426cfea0136
Autor:
Zhen Huang, Kun-Peng Zhu, Jian-Ping Hu, Yu-Run Zhu, En-Jie Xu, Xiao-Long Ma, Yong-Jie Wang, Chun-Lin Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: Acetabular metastasis is a type of metastatic bone cancer, and it mainly metastasizes from cancers such as lung cancer, breast cancer, and renal carcinoma. Acetabular metastasis often causes severe pain, pathological fractures, and hyperc
Externí odkaz:
https://doaj.org/article/7cd554044149446389d9f01a5c68541b
Autor:
Ya‐Nan Li, Hong‐Wen Liang, Chun‐Lin Zhang, Yan‐Mei Qiu, David Wang, Hai‐Ling Wang, An‐Qi Chen, Can‐Dong Hong, Lei Wang, Hao Wang, Bo Hu
Publikováno v:
Advanced Science, Vol 10, Iss 3, Pp n/a-n/a (2023)
Abstract Diabetic retinopathy (DR) is the leading cause of vision loss in working age population. Intravitreal injection of anti‐VEGF antibody is widely used in clinical practice. However, about 27% of patients show poor response to anti‐VEGF the
Externí odkaz:
https://doaj.org/article/39e12f821244478493f183742cb84db3
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Accumulating evidence has shown that circular RNA (circRNA) dysregulation is involved in various types of cancer, including osteosarcoma (OS). Nevertheless, the role and mechanism of circRNAs in OS progression and chemoresistance remain elus
Externí odkaz:
https://doaj.org/article/d25c4ac1a19e4b4882079116abf2371d
Autor:
Nian-Ting Yao, Qian Zheng, Zi-Qian Xu, Jian-Hong Yin, Lin-Guang Lu, Qi Zuo, Su Yang, Chun-Lin Zhang, Ling Jiao, Qiang Shi
Publikováno v:
Chinese Medical Journal, Vol 133, Iss 12, Pp 1448-1455 (2020)
Abstract. Parkinson disease (PD) is the second-most common neurodegenerative disorder. Its main pathological mechanism is the selective degeneration and deletion of dopaminergic neurons in the dense part of the substantia nigra and the damage of dopa
Externí odkaz:
https://doaj.org/article/c3d8b99756c947c3b6ae8710f5673930
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic transformation. The rapid activation of immune cells plays a critical role
Externí odkaz:
https://doaj.org/article/b7ca78b938ff4aec8fe33b3af5ec3d38
Publikováno v:
Chinese Medical Journal, Vol 132, Iss 22, Pp 2757-2759 (2019)
Externí odkaz:
https://doaj.org/article/262a93d421764b4a98256ef506030f55
Autor:
Jie‐hong Wu, Ya‐nan Li, An‐qi Chen, Can‐dong Hong, Chun‐lin Zhang, Hai‐ling Wang, Yi‐fan Zhou, Peng‐Cheng Li, Yong Wang, Ling Mao, Yuan‐peng Xia, Quan‐wei He, Hui‐juan Jin, Zhen‐yu Yue, Bo Hu
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 2, Pp n/a-n/a (2020)
Abstract Diabetic retinopathy (DR) is a common complication of diabetes and leads to blindness. Anti‐VEGF is a primary treatment for DR. Its therapeutic effect is limited in non‐ or poor responders despite frequent injections. By performing a com
Externí odkaz:
https://doaj.org/article/14c29eb98628469881203dfdcc387171