Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Chun-Lin Deng"'
Autor:
David King, Chelsea R. Wilson, Lukas Herron, Chun-Lin Deng, Shams Mehdi, Pratyush Tiwary, Fraser Hof, Lyle Isaacs
Publikováno v:
Organic & Biomolecular Chemistry. 20:7429-7438
The molecular recognition properties of Pillar[6]MaxQ toward methylated amino acids, amino acid amides, and peptides is investigated by a combination of 1H NMR, ITC, indicator displacements assays, and molecular dynamics simulations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cf7ebfee14dac0ffdb3e4d3fbf1d7c
https://doi.org/10.1039/d2ob01487d
https://doi.org/10.1039/d2ob01487d
Autor:
Adam T. Brockett, Weijian Xue, David King, Chun-Lin Deng, Canjia Zhai, Michael Shuster, Shivangi Rastogi, Volker Briken, Matthew R. Roesch, Lyle Isaacs
Pillar[6]MaxQ (P6AS) functions as an in vivo sequestration agent for methamphetamine and fentanyl. We use 1H NMR and isothermal titration calorimetry to glean information on the geometry and strength of the P6AS•drug complexes. P6AS forms tight com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea66fd5eb45ba93ec9e22255c7cd5ac6
https://doi.org/10.26434/chemrxiv-2022-0nfz0
https://doi.org/10.26434/chemrxiv-2022-0nfz0
Publikováno v:
Chem Soc Rev
Pharmaceutical agents, drugs of abuse, and toxic substances have a large impact, positive and negative, on modern society. Efforts to mitigate the side effects of pharmaceuticals and counteract the life threatening effects of drugs of abuse and toxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6affd2d08ef49c3a1caf8bb4e2c18fab
https://doi.org/10.1039/d0cs00454e
https://doi.org/10.1039/d0cs00454e
Publikováno v:
New J Chem
We report an investigation of the complexation between a water soluble pillararene host (WP6) and a panel of hydrophobic cationic guests (G1 – G20) by a combination of (1)H NMR spectroscopy and isothermal titration calorimetry in phosphate buffered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b38509dbdfd3a446ffccfe6ba54e5
https://europepmc.org/articles/PMC8896905/
https://europepmc.org/articles/PMC8896905/
Autor:
Volker Briken, Suvenika Perera, Ming Cheng, Adam T. Brockett, Steven Murkli, Chun-Lin Deng, Delaney DiMaggio, Lyle Isaacs, Matthew R. Roesch, Michael Shuster
Publikováno v:
Chemistry
We report the synthesis of two new acyclic sulfated acyclic CB[n]-type receptors (TriM0 and Me(4)TetM0) and investigations of their binding properties toward a panel of drugs of abuse (1 – 13) by a combination of (1)H NMR spectroscopy and isotherma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6013eae5dfff929e6f99f2eb17ae515b
https://pubmed.ncbi.nlm.nih.gov/34613641
https://pubmed.ncbi.nlm.nih.gov/34613641
Autor:
Jeremy P. Bard, Chun-Lin Deng, Darren W. Johnson, Michael M. Haley, Hannah J. Bates, Lev N. Zakharov
Publikováno v:
The Journal of Organic Chemistry. 85:85-91
We report the synthesis and characterization of P-phenyl modified phosphorus- and nitrogen-containing phosphaquinolinone heterocycles. The change from -OPh to -Ph results in a marked increase in the quantum yield of the scaffold as well as a moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b221588f6966664ce14139197cf4a7ba
https://doi.org/10.1021/acs.joc.9b02132
https://doi.org/10.1021/acs.joc.9b02132
Publikováno v:
Organic Letters. 21:6427-6431
A straightforward method for the preparation of non-K region fused phosphorus- and nitrogen-containing (PN)-heterocyclic pyrenes has been accomplished. Their structural, photophysical, and electrochemical properties have been fully investigated. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feed2654a1228b499b2a32c0aecfd8ff
https://doi.org/10.1021/acs.orglett.9b02332
https://doi.org/10.1021/acs.orglett.9b02332
Autor:
Jeremy P. Bard, I. David Reingold, Michael M. Haley, Chun-Lin Deng, Wataru Nojo, Daniel T. Chase
Publikováno v:
ChemPlusChem. 84:1391-1395
We have prepared nine structural isomers of a tetrakis(arylethynyl)benzene chromophore functionalized with 4-butoxyphenyl and pyridyl units as the respective donor and acceptor units and examined their steady-state spectroscopic parameters to study h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1cb218088fc0206269af9da301aaff
https://doi.org/10.1002/cplu.201900266
https://doi.org/10.1002/cplu.201900266
Autor:
Chun‐Lin Deng, Jeremy P. Bard, Jessica A. Lohrman, Joshua E. Barker, Lev N. Zakharov, Darren W. Johnson, Michael M. Haley
Publikováno v:
Angewandte Chemie International Edition. 58:3934-3938
We describe two novel hybrid receptors combining a phosphorus-/nitrogen-containing (PN) phosphonamidate heterocycle with urea recognition units in an arylethynyl backbone. Structural, spectroscopic and computational studies reveal that the origin of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e2df03dbc337520a8483054ad9d4cd
https://doi.org/10.1002/anie.201814431
https://doi.org/10.1002/anie.201814431
Autor:
Chun-Lin Deng, Lev N. Zakharov, Jeremy P. Bard, Darren W. Johnson, Jacob M. Odulio, Hannah C. Richardson, Michael M. Haley, Paul Ha-Yeon Cheong, Joshua E. Barker
Publikováno v:
Organic Chemistry Frontiers. 6:1257-1265
We have rationally designed and synthesized a library of phosphaquinolinone derivatives containing various electron-donating and -withdrawing groups on two positions of the scaffold. Distinct trends are observed between the substituents on R1 and R2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2a53920ed8846a4d0054dbfde3cbdc
https://doi.org/10.1039/c9qo00199a
https://doi.org/10.1039/c9qo00199a