The Effectiveness of Early Food Introduction in Preventing Childhood Allergic Diseases: Protocol for a Systematic Review and Meta-Analysis

Autor: Aisha Fadhilah Abang Abdullah, Nor Asiah Muhamad, Rimah Melati Ab Ghani, Nur Hasnah Maamor, Fatin Norhasny Leman, Chun Lai Too, Intan Hakimah Ismail, Nor Afiah Mohd Zulkefli, Ahmad Iqmer Nashriq Mohd Nazan, Salmiah Md Said

Publikováno v: JMIR Research Protocols, Vol 12, p e46816 (2023)

BackgroundAllergic diseases affect around 40% of the pediatric population worldwide. The coexistence of asthma, allergic rhinitis, eczema, and food allergy renders allergy treatment and prevention challenging. Infant feeding strategies recommend avoi

Externí odkaz: https://doaj.org/article/dea03097b50b46c18e310f825e0c7dc9

The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study

Autor: Lay Kim Tan, Chun Lai Too, Lina Marcela Diaz-Gallo, Sulaiman Wahinuddin, Ing Soo Lau, Hussein Heselynn, Shahril Nor-Shuhaila, Suk Chyn Gun, Mageswaran Eashwary, Mohamed Said Mohd-Shahrir, Mohd Mokhtar Ainon, Rosman Azmillah, Othman Muhaini, Murad Shahnaz, Lars Alfredsson, Lars Klareskog, Leonid Padyukov

Publikováno v: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)

Abstract Background Fine-mapping of human leukocyte antigen (HLA) region for rheumatoid arthritis (RA) risk factors has identified several HLA alleles and its corresponding amino acid residues as independent signals (i.e., HLA-A, HLA-B, HLA-DPB1, and

Externí odkaz: https://doaj.org/article/4db19290c04946a5a696b84802f12837

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Autor: Kazuyoshi, Ishigaki, Saori, Sakaue, Chikashi, Terao, Yang, Luo, Kyuto, Sonehara, Kensuke, Yamaguchi, Tiffany, Amariuta, Chun Lai, Too, Vincent A, Laufer, Ian C, Scott, Sebastien, Viatte, Meiko, Takahashi, Koichiro, Ohmura, Akira, Murasawa, Motomu, Hashimoto, Hiromu, Ito, Mohammed, Hammoudeh, Samar Al, Emadi, Basel K, Masri, Hussein, Halabi, Humeira, Badsha, Imad W, Uthman, Xin, Wu, Li, Lin, Ting, Li, Darren, Plant, Anne, Barton, Gisela, Orozco, Suzanne M M, Verstappen, John, Bowes, Alexander J, MacGregor, Suguru, Honda, Masaru, Koido, Kohei, Tomizuka, Yoichiro, Kamatani, Hiroaki, Tanaka, Eiichi, Tanaka, Akari, Suzuki, Yuichi, Maeda, Kenichi, Yamamoto, Satoru, Miyawaki, Gang, Xie, Jinyi, Zhang, Christopher I, Amos, Edward, Keystone, Gertjan, Wolbink, Irene, van der Horst-Bruinsma, Jing, Cui, Katherine P, Liao, Robert J, Carroll, Hye-Soon, Lee, So-Young, Bang, Katherine A, Siminovitch, Niek, de Vries, Lars, Alfredsson, Solbritt, Rantapää-Dahlqvist, Elizabeth W, Karlson, Sang-Cheol, Bae, Robert P, Kimberly, Jeffrey C, Edberg, Xavier, Mariette, Tom, Huizinga, Philippe, Dieudé, Matthias, Schneider, Martin, Kerick, Joshua C, Denny, Koichi, Matsuda, Keitaro, Matsuo, Tsuneyo, Mimori, Fumihiko, Matsuda, Keishi, Fujio, Yoshiya, Tanaka, Atsushi, Kumanogoh, Matthew, Traylor, Cathryn M, Lewis, Stephen, Eyre, Huji, Xu, Richa, Saxena, Thurayya, Arayssi, Yuta, Kochi, Katsunori, Ikari, Masayoshi, Harigai, Peter K, Gregersen, Kazuhiko, Yamamoto, S, Louis Bridges, Leonid, Padyukov, Javier, Martin, Lars, Klareskog, Yukinori, Okada, Soumya, Raychaudhuri

Publikováno v: Nature Genetics, 54, 1640-1651
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet

Multi-ancestry genome-wide association analyses identify 124 risk loci for rheumatoid arthritis, of which 34 are novel. A polygenic risk score based on multi-ancestry data showed comparable performance between populations of European and East Asian a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e48733cf2e8205acbde830a39b0265
https://doi.org/10.1038/s41588-022-01213-w

The Effectiveness of Early Food Introduction in Preventing Childhood Allergic Diseases: Protocol for Systematic Review and Meta-Analysis (Preprint)

Autor: Aisha Fadhilah Abang Abdullah, Nor Asiah Muhamad, Rimah Melati Ab Ghani, Nur Hasnah Maamor, Fatin Norhasny Leman, Chun-Lai Too, Intan Hakimah Ismail, Nor Afiah Mohd. Zulkefli, Ahmad Iqmer Nashriq Mohd Nazan, Salmiah Md. Said

Publikováno v: JMIR Research Protocols.

BACKGROUND Allergic diseases affects around 40% of children population worldwide. The coexistence of asthma, allergic rhinitis (AR), eczema, and food allergy (FA) renders allergy treatment and prevention challenging. Infant feeding strategies recomme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196f75516976fdf5075ac03768e4d9f5
https://doi.org/10.2196/46816

Genetic Biomarkers as Predictors of Response to Tocilizumab in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

Autor: Sivakami Janahiraman, Chun Lai Too, Kai Wei Lee, Nor Shuhaila Shahril, Chee Onn Leong

Publikováno v: Genes. 13(7)

Rheumatoid arthritis (RA) is a lifelong, debilitating disease which incredibly impacts a patient’s quality of life if not treated to the optimal target. The clinical response of tocilizumab, an interleukin-6 (IL-6) inhibitor, is associated with sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23290fdd0992f7051c2559b6343c44ed
https://pubmed.ncbi.nlm.nih.gov/35886067