Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Chun-Hung Chan"'
Publikováno v:
Mathematics, Vol 12, Iss 15, p 2388 (2024)
Manifold learning-based approaches have emerged as prominent techniques for dimensionality reduction. Among these methods, t-Distributed Stochastic Neighbor Embedding (t-SNE) and Uniform Manifold Approximation and Projection (UMAP) stand out as two o
Externí odkaz:
https://doaj.org/article/422584449fa94cb08d95be7371a429f5
Autor:
Galliano Zanello, Macarena Garrido‐Estepa, Ana Crespo, Daniel O'Connor, Rima Nabbout, Christina Waters, Anthony Hall, Maurizio Taglialatela, Chun‐Hung Chan, David A Pearce, Marc Dooms, Philip John Brooks
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 7, Pp n/a-n/a (2023)
Abstract Rare diseases affect over 400 million people worldwide and less than 5% of rare diseases have an approved treatment. Fortunately, the number of underlying disease etiologies is far less than the number of diseases, because many rare diseases
Externí odkaz:
https://doaj.org/article/6fff0fada4b5495890eea6b6f2758b6c
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Rare disease patients face many challenges including diagnostic delay, misdiagnosis and lack of therapies. However, early access to diagnosis and therapies can modify the management and the progression of diseases, which in return positively
Externí odkaz:
https://doaj.org/article/0b5144fbb40947c9b552b841b285b8ce
Autor:
Ainslie Tisdale, Christine M. Cutillo, Ramaa Nathan, Pierantonio Russo, Bryan Laraway, Melissa Haendel, Douglas Nowak, Cindy Hasche, Chun-Hung Chan, Emily Griese, Hugh Dawkins, Oodaye Shukla, David A. Pearce, Joni L. Rutter, Anne R. Pariser
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Rare diseases (RD) are a diverse collection of more than 7–10,000 different disorders, most of which affect a small number of people per disease. Because of their rarity and fragmentation of patients across thousands of differen
Externí odkaz:
https://doaj.org/article/bd3dbd832fd6404ca21a136660f71696
Publikováno v:
Disease Models & Mechanisms, Vol 5, Iss 2, Pp 191-199 (2012)
SUMMARY BTN1, the yeast homolog to human CLN3 (which is defective in Batten disease), has been implicated in the regulation of vacuolar pH, potentially by modulating vacuolar-type H+-ATPase (V-ATPase) activity. However, we report that Btn1p and the V
Externí odkaz:
https://doaj.org/article/3c6d4f9fa3f34a1588376fb65621f81b
Autor:
Amanda Getty, Attila D Kovács, Tímea Lengyel-Nelson, Andrew Cardillo, Caitlin Hof, Chun-Hung Chan, David A Pearce
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66203 (2013)
Juvenile CLN3 disease (formerly known as juvenile neuronal ceroid lipofuscinosis) is a fatal childhood neurodegenerative disorder caused by mutations in the CLN3 gene. CLN3 encodes a putative lysosomal transmembrane protein with unknown function. Pre
Externí odkaz:
https://doaj.org/article/11408540151d44bb9ab889b54de72bf1
Autor:
Chun-Hung Chan, 詹駿鴻
101
In maritime litigation practice, whether the case is accepted by a court of competent jurisdiction has always been to act the attention to the lawyers. Also, the trial judge, can not avoid this question. As Canadian scholar William Tetley wr
In maritime litigation practice, whether the case is accepted by a court of competent jurisdiction has always been to act the attention to the lawyers. Also, the trial judge, can not avoid this question. As Canadian scholar William Tetley wr
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/41009738793245570492
Autor:
Christine M. Cutillo, Hugh Dawkins, Oodaye Shukla, David A. Pearce, Pierantonio Russo, Cindy Hasche, Douglas Nowak, Ramaa Nathan, Ainslie Tisdale, Bryan Laraway, Melissa Haendel, Joni L. Rutter, Emily R. Griese, Chun-Hung Chan, Anne Pariser
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-18 (2021)
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases
Background Rare diseases (RD) are a diverse collection of more than 7–10,000 different disorders, most of which affect a small number of people per disease. Because of their rarity and fragmentation of patients across thousands of different disorde
Publikováno v:
Sports Medicine - Open, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Background Studies have demonstrated that exercise can mitigate the intensity of menstrual pain in primary dysmenorrhea, but the most effective type of exercise remains unclear. The objective of this systematic review and network meta-analys
Externí odkaz:
https://doaj.org/article/67733249ed314e3db6eaa8c91eefd9eb