Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Chun-Hau Chen"'
Autor:
Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun-Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S. Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9b0bb45b90e24907906ca667d17685dc
Autor:
Shingo Kozono, Yu-Min Lin, Hyuk-Soo Seo, Benika Pinch, Xiaolan Lian, Chenxi Qiu, Megan K. Herbert, Chun-Hau Chen, Li Tan, Ziang Jeff Gao, Walter Massefski, Zainab M. Doctor, Brian P. Jackson, Yuanzhong Chen, Sirano Dhe-Paganon, Kun Ping Lu, Xiao Zhen Zhou
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Arsenic trioxide and all-trans retinoic acid combination safely cures human acute promyelocytic leukemia. Here, the authors show that this combination has potent anticancer activity in triple negative breast cancer by cooperatively targeting Pin1, a
Externí odkaz:
https://doaj.org/article/acea0fc0a384452499f5273e12f88166
Autor:
Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun-Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Abstract Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing
Externí odkaz:
https://doaj.org/article/f59a26dd71a44b3c90785a69ce33bbf8
Autor:
Martin Balastik, Xiao Zhen Zhou, Meritxell Alberich-Jorda, Romana Weissova, Jakub Žiak, Maria F. Pazyra-Murphy, Katharina E. Cosker, Olga Machonova, Iryna Kozmikova, Chun-Hau Chen, Lucia Pastorino, John M. Asara, Adam Cole, Calum Sutherland, Rosalind A. Segal, Kun Ping Lu
Publikováno v:
Cell Reports, Vol 13, Iss 4, Pp 812-828 (2015)
Axon guidance relies on precise translation of extracellular signal gradients into local changes in cytoskeletal dynamics, but the molecular mechanisms regulating dose-dependent responses of growth cones are still poorly understood. Here, we show tha
Externí odkaz:
https://doaj.org/article/59143a7db6614643bea7b694861dcc5e
Autor:
Chun-Hau Chen, Wenzong Li, Rukhsana Sultana, Mi-Hyeon You, Asami Kondo, Koorosh Shahpasand, Byeong Mo Kim, Man-Li Luo, Morris Nechama, Yu-Min Lin, Yandan Yao, Tae Ho Lee, Xiao Zhen Zhou, Aaron M. Swomley, D. Allan Butterfield, Yan Zhang, Kun Ping Lu
Publikováno v:
Neurobiology of Disease, Vol 76, Iss , Pp 13-23 (2015)
The unique proline isomerase Pin1 is pivotal for protecting against age-dependent neurodegeneration in Alzheimer's disease (AD), with its inhibition providing a molecular link between tangle and plaque pathologies. Pin1 is oxidatively modified in hum
Externí odkaz:
https://doaj.org/article/d411781e221e406fa456c9193b66ddf6
Autor:
Man-Li Luo, Chang Gong, Chun-Hau Chen, Hai Hu, Pengyu Huang, Min Zheng, Yandan Yao, Shuo Wei, Gerburg Wulf, Judy Lieberman, Xiao Zhen Zhou, Erwei Song, Kun Ping Lu
Publikováno v:
Cell Reports, Vol 11, Iss 1, Pp 111-124 (2015)
Proline-directed phosphorylation is regulated by the prolyl isomerase Pin1, which plays a fundamental role in driving breast cancer stem-like cells (BCSCs). Rab2A is a small GTPase critical for vesicle trafficking. Here, we show that Pin1 increases R
Externí odkaz:
https://doaj.org/article/3502e6cf67de428084eb6fcb36a0fe94
Autor:
Chun-Hau Chen, 陳俊豪
93
Death-associated protein kinase (DAPK) is a death domain (DD)-containing serine/threonine kinase identified by its participation in the interferon-��-induced apoptosis. Subsequent studies revealed a broad involvement of DAPK in apoptosis
Death-associated protein kinase (DAPK) is a death domain (DD)-containing serine/threonine kinase identified by its participation in the interferon-��-induced apoptosis. Subsequent studies revealed a broad involvement of DAPK in apoptosis
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/47922186222590929126
Autor:
Chun-Hau Chen, 陳俊豪
91
Chitosan hydrolysates of 0, 5, 10, 20 and 30% hydrolyzation degree were produced from the highly-deaclylated chitosan (85% deacelylation) with the chitin-immobilized chitosanase. Soymilk, in addition, was obtained by soaking soybean overnight
Chitosan hydrolysates of 0, 5, 10, 20 and 30% hydrolyzation degree were produced from the highly-deaclylated chitosan (85% deacelylation) with the chitin-immobilized chitosanase. Soymilk, in addition, was obtained by soaking soybean overnight
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/83037713399322164643
Autor:
Chun-Hau Chen, 陳俊豪
87
Fengycin is an antifungal lipopeptidic antibiotics produced by Bacillus subtilis F29-3. Ealier studies demostrated that fengycin peptide contains 10 amino acids, which is synthesized nonribosomally by peptide synthetases. The purpose of this
Fengycin is an antifungal lipopeptidic antibiotics produced by Bacillus subtilis F29-3. Ealier studies demostrated that fengycin peptide contains 10 amino acids, which is synthesized nonribosomally by peptide synthetases. The purpose of this
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/33734038568823612197
Autor:
Gordon J. Freeman, Sabina Signoretti, Antonio R. Arulanandam, David F. McDermott, Jie Zhu, Jo Soden, Ping Hua, Baogong Zhu, Maura Sticco-Ivins, Jean-Christophe Pignon, Paul J. Catalano, Opeyemi A. Jegede, Chun-Hau Chen, Samuel S. Freeman, Alyssa N. Klee, Kathleen M. Mahoney, Julie C. Konge, Abdulla Berjis, Rupal S. Bhatt
Blockade of the PD1 pathway is a broadly effective cancer therapy, but additional immune-inhibitory pathways contribute to tumor immune evasion. HERV–H LTR-associating 2 (HHLA2; also known as B7H5 and B7H7) is a member of the B7 family of immunoreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332b94b9c7b92f3f2b93b94a42d4aa9f
https://doi.org/10.1158/2326-6066.c.6550380.v1
https://doi.org/10.1158/2326-6066.c.6550380.v1