Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Chun-Han Chen"'
Autor:
Han-Lin Hsu, Bo-Jyun Lin, Yu-Chen Lin, Chih-Chieh Tu, Nham-Linh Nguyen, Ching-Chiung Wang, Mei-Chuan Chen, Chun-Han Chen
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8138-8151 (2023)
EGFR tyrosine kinase inhibitors (TKIs) are the first-line treatment for advanced EGFR-mutated non-small-cell lung cancer (NSCLC). However, NSCLC patients with wild-type EGFR and KRAS mutation are ineligible for EGFR-TKIs. Therefore, the discovery of
Externí odkaz:
https://doaj.org/article/1d73421dea6344dab96cebadb0c59579
Autor:
Pei-Chien Tsai, Wei-Jung Chuang, Albert Min-Shan Ko, Jui-Shuan Chen, Cheng-Hsun Chiu, Chun-Han Chen, Yung-Hsin Yeh
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Patients with type 2 diabetes are at increased risk for cardiovascular diseases. Sodium-glucose transport 2 inhibitors (SGLT2i) have been shown to enhance cardiovascular health since their debut as a second-line therapy for diabet
Externí odkaz:
https://doaj.org/article/4217f22f54db41a5860c6436a707aa13
Autor:
Chun-Han Chang, Bo-Jyun Lin, Chun-Han Chen, Nham-Linh Nguyen, Tsung-Han Hsieh, Jui-Hsin Su, Mei-Chuan Chen
Publikováno v:
Marine Drugs, Vol 21, Iss 2, p 73 (2023)
Bladder cancer (BC) is one of the most prevalent cancers worldwide. However, the recurrence rate and five-year survival rate have not been significantly improved in advanced BC, and new therapeutic strategies are urgently needed. The anticancer activ
Externí odkaz:
https://doaj.org/article/c0b25fc7feda408b8ce6f84b4c96d4a1
Publikováno v:
Plant Direct, Vol 4, Iss 9, Pp n/a-n/a (2020)
Abstract Small ubiquitin‐like modifier (SUMO) conjugation, or SUMOylation, is a reversible post‐translational modification that is important for regulation of many cellular processes including cell division cycle in the eukaryotic kingdom. Howeve
Externí odkaz:
https://doaj.org/article/c7606b2b166748ec976b277132213e96
Autor:
Ming-Horng Tsai, Chiang-Wen Lee, Lee-Fen Hsu, Shu-Yu Li, Yao-Chang Chiang, Ming-Hsueh Lee, Chun-Han Chen, Hwey-Fang Liang, Jia-Mei How, Pey-Jium Chang, Ching-Mei Wu, I-Ta Lee
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 377-388 (2017)
Ang II has been involved in the pathogenesis of cardiovascular diseases, and matrix metalloproteinase-9 (MMP-9) induced migration of human aortic smooth muscle cells (HASMCs) is the most common and basic pathological feature. Carbon monoxide (CO), a
Externí odkaz:
https://doaj.org/article/857731228a4c4d8898802c8a62050a55
Autor:
Min-Ru Ho, Tsung-Ting Tsai, Chia-Ling Chen, Ming-Kai Jhan, Cheng-Chieh Tsai, Yi-Chao Lee, Chun-Han Chen, Chiou-Feng Lin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Dengue virus (DENV) infection in neuronal cells was speculated to trigger neuropathy. Herein, we determined the blockade of DENV infection by targeting endocytic pathways in vitro and in vivo. In DENV-infected mouse brains, we previously sho
Externí odkaz:
https://doaj.org/article/9000d0df5a274de08cebf48ccb2294cd
Autor:
Yu-Jui Fan, Fu-Lun Chen, Jian-Chiun Liou, Yu-Wen Huang, Chun-Han Chen, Zi-Yin Hong, Jia-De Lin, Yu-Cheng Hsiao
Publikováno v:
Polymers, Vol 12, Iss 2, p 395 (2020)
We developed a new format for liquid crystal (LC)-based multi-microfluidic immunoassays, hosted on a polydimethylsiloxane substrate. In this design, the orientations of the LCs were strongly affected by the interface between the four microchannel wal
Externí odkaz:
https://doaj.org/article/a4fb09ba8b784746a0c91641f44a50cb
Publikováno v:
Journal of the Formosan Medical Association, Vol 111, Iss 10, Pp 580-583 (2012)
Cystic fibrosis (CF) is an inherited disease of the secretory glands caused by mutations of the cystic fibrosis transmembrane regulator (CFTR) gene. The clinical manifestations of CF are repetitive lung infections, biliary cirrhosis, pancreatic abnor
Externí odkaz:
https://doaj.org/article/4dfa54dbab6e458cad79f6998351409c
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44093 (2012)
α-Tomatine, a tomato glycoalkaloid, has been reported to possess antibiotic properties against human pathogens. However, the mechanism of its action against leukemia remains unclear. In this study, the therapeutic potential of α-tomatine against le
Externí odkaz:
https://doaj.org/article/830d1db1cb00483cba24ac52b6f5e390
Autor:
Tzu-Pi Huang, Dean Der-Syh Tzeng, Amy C L Wong, Chun-Han Chen, Kuan-Min Lu, Ya-Huei Lee, Wen-Di Huang, Bing-Fang Hwang, Kuo-Ching Tzeng
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42124 (2012)
Citrus bacterial canker caused by Xanthomonas axonopodis pv. citri is a devastating disease resulting in significant crop losses in various citrus cultivars worldwide. A biocontrol agent has not been recommended for this disease. To explore the poten
Externí odkaz:
https://doaj.org/article/bdf6fbc328f9426086da8e0a73bc29d1