Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Chun-Fung Sin"'
Autor:
Xiao Wang, Chun-fung Sin, Kay-Cheong Teo, William C. Y. Leung, Yuen-Kwun Wong, Roxanna K. C. Liu, Joshua W. Fok, Bonaventure Y. Ip, Hon Hang Kwan, Tsz Ching Lee, Bun Sheng, Edwin Kin-Keung Yip, Desmond Y. H. Yap, Hao Luo, Kui-Kai Lau
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAlthough renal dysfunction is associated with adverse clinical outcomes in patients with atrial fibrillation (AF) following stroke, the impact of renal function variability is unclear.AimThis study aimed to assess the association between re
Externí odkaz:
https://doaj.org/article/e19339dc63494ca480aa138da2bd6909
Autor:
Rahman Ud Din, Anan Jiao, Yinxia Qiu, Aarmann Anil Mohinani Mohan, Kei-Ching Yuen, Hoi-Tung Wong, Timothy Ming-Hun Wan, Phoebe On-Yi Wong, Chun-Fung Sin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14646 (2023)
T lymphoblastic leukemia (T-ALL) is an aggressive haematolymphoid malignancy comprising 15% of acute lymphoblastic leukemia (ALL). Although its prognosis has improved with intensive chemotherapy, the relapse/refractory disease still carries a dismal
Externí odkaz:
https://doaj.org/article/3990d31a4026454b9b7e7c5a6429f551
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction: Accumulation of apixaban in plasma is a major concern in patients with chronic kidney disease (CKD). Studies that investigated plasma apixaban level in CKD patients and its association with clinically significant events are scarce.Metho
Externí odkaz:
https://doaj.org/article/773449e71e454a0fb37ef4ab54a25620
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction Drug accumulation of rivaroxaban is a concern in patients with chronic kidney disease (CKD). Data regarding the plasma rivaroxaban levels in early CKD patients and its relationship with clinical events is lacking. Methods Early CKD patie
Externí odkaz:
https://doaj.org/article/e3ac1f36969f4702924bca8afa0c26b2
Autor:
Kitty Yu-Yeung Lau, Kei-Shing Ng, Ka-Wai Kwok, Kevin Kin-Man Tsia, Chun-Fung Sin, Ching-Wan Lam, Varut Vardhanabhuti
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
BackgroundTo better understand the different clinical phenotypes across the disease spectrum in patients with COVID-19 using an unsupervised machine learning clustering approach.Materials and MethodsA population-based retrospective study was conducte
Externí odkaz:
https://doaj.org/article/29085441883d4dea818d456b84f346b0
Autor:
Chun-fung Sin, Pui-hei Marcus Man
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Acute lymphoblastic leukaemia (ALL) is an aggressive haematolymphoid malignancy. The prognosis of ALL is excellent in paediatric population, however the outcome of relapse/refractory disease is dismal. Adult ALL has less favourable prognosis and rela
Externí odkaz:
https://doaj.org/article/acba01641f9d47f8b3d8f3e708abd568
Autor:
Chun-fung Sin, Pui-hei Marcus Man
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a distinct subtype of T lymphoblastic leukemia (T-ALL) identified in 2009, due to its unique immunophenotypic and genomic profile. The outcome of patients was poor in earlier studies, a
Externí odkaz:
https://doaj.org/article/e6709299e1584832bc967422cf3e0cc3
Autor:
Dandan Wang, Lichuan Zheng, Bowie Yik Ling Cheng, Chun-Fung Sin, Runsheng Li, Sze Pui Tsui, Xinyu Yi, Alvin Chun Hang Ma, Bai Liang He, Anskar Yu Hung Leung, Xuan Sun
Publikováno v:
Oncogene. 42:1272-1281
Isocitrate dehydrogenase 2 (IDH2) mutations occur in more than 15% of cytogenetically normal acute myeloid leukemia (CN-AML) but comparative studies of their roles in leukemogenesis have been scarce. We generated zebrafish models of IDH2R172K and IDH
Autor:
Sze Keong Tey, Samuel Wan Ki Wong, Janice Yuen Tung Chan, Xiaowen Mao, Tung Him Ng, Cherlie Lot Sum Yeung, Zoe Leung, Hiu Ling Fung, Alexander Hin Ning Tang, Danny Ka Ho Wong, Lung-Yi Mak, Man-Fung Yuen, Chun-Fung Sin, Irene Oi-Lin Ng, Stephanie Kwai Yee Ma, Terence Kin Wah Lee, Peihua Cao, Kebo Zhong, Yi Gao, Jing Ping Yun, Judy Wai Ping Yam
Publikováno v:
Journal of Hepatology. 76:883-895
Extracellular vesicles (EVs) play a pivotal role in connecting tumor cells with their local and distant microenvironments. Herein, we aimed to understand the role (on a molecular basis) patient-derived EVs play in modulating cancer stemness and tumor
Publikováno v:
Cancer Research. 83:6199-6199
Acute lymphoblastic leukemia (ALL) is an aggressive hematolymphoid malignancy and the prognosis is poor in adults with long-term survival of only 30% due to the high prevalence of high-risk subtypes. Therefore, there is an urgent need to develop nove