Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chun-Fai Lai"'
Publikováno v:
Journal of Biological Chemistry. 274:7793-7802
Interleukin (IL)-6 is a major regulator of hepatic acute-phase plasma protein (APP) genes. The membrane-proximal 133-amino acid cytoplasmic domain of glycoprotein (gp) 130, containing one copy of the Box3 motif, is sufficient to transmit a productive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c2e78d45f70dd6b8792dd6886ec397
https://doi.org/10.1074/jbc.274.12.7793
https://doi.org/10.1074/jbc.274.12.7793
Autor:
Christian H. Geisler, Leslie E. Blumenson, Michael A. Caligiuri, Jeffrey Schriber, J. Jurlander, Satwant K. Narula, Chuan-Chu Chou, Chun-Fai Lai, Jimmy C. Tan, Heinz Baumann
Publikováno v:
Blood. 89:4146-4152
B-cell chronic lymphocytic leukemia (B-CLL) cells accumulate in vivo in the G0/G1 phase of the cell cycle, suggesting that their malignant expansion is due, at least in part, to a delay in cell death. However, the cellular or molecular factors respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58431ad8f1e6ff98d60bd3919c337ecb
https://doi.org/10.1182/blood.v89.11.4146
https://doi.org/10.1182/blood.v89.11.4146
Autor:
Heinz Baumann, Pascal S. Bailon, Chun-Fai Lai, Marlene Dembski, K. K. Morella, David White, Louis A. Tartaglia, Hongkyun Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 93:8374-8378
The leptin receptor (OB-R) is a single membrane-spanning protein that mediates the weight regulatory effects of leptin (OB protein). The mutant allele (db) of the OB-R gene encodes a protein with a truncated cytoplasmic domain that is predicted to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f51e76312b5670e5f27c0423d739b8
https://doi.org/10.1073/pnas.93.16.8374
https://doi.org/10.1073/pnas.93.16.8374
Autor:
Heinz Baumann, Chun-Fai Lai
Publikováno v:
Blood. 87:4143-4148
Interleukin-1 (IL-1) is a proinflammatory cytokine that participates in the activation of the acute-phase plasma protein genes in hepatic cells during infection and injury. In human hepatoma HepG2 and Hep3B cells, IL-1 beta induced production of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb1ec8c0e3a61e218cfca288ab6b1ff
https://doi.org/10.1182/blood.v87.10.4143.bloodjournal87104143
https://doi.org/10.1182/blood.v87.10.4143.bloodjournal87104143
Autor:
Nelson D. Horseman, Heinz Baumann, K. K. Morella, Susana P. Campos, Juergen Ripperger, Chun-Fai Lai, David P. Gearing, Yanping Wang, G H Fey
Publikováno v:
Journal of Biological Chemistry. 270:23254-23257
Transient transfection of expression vectors for various members of the hematopoietin receptor family and STAT proteins into COS-1 cells indicated that each receptor was capable of stimulating the DNA binding activity of STAT1, STAT3, and STAT5B. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8a091cee4382e0c7555e8a499e9a1e
https://doi.org/10.1074/jbc.270.40.23254
https://doi.org/10.1074/jbc.270.40.23254
Autor:
Heinz Baumann, Chun-Fai Lai, K. K. Morella, Juergen Ripperger, Georg H. Fey, Susana P. Campos, Yanping Wang, David P. Gearing
Publikováno v:
Blood. 86:1671-1679
To determine the specificity of signal transducer and activator of transcription (STAT) protein activation by box 3 motif-deficient hematopoietin receptors, expression vectors encoding the receptors for growth hormone, interleukin-3 (IL-3), and IL-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e390dc4cab37be0f3fc2b029b8bf0f36
https://doi.org/10.1182/blood.v86.5.1671.bloodjournal8651671
https://doi.org/10.1182/blood.v86.5.1671.bloodjournal8651671
Autor:
S Kumaki, K. K. Morella, E Bruno, Chun-Fai Lai, L Benit, R Hoffman, Martin Timour, HM Wang, J Fu, L Murray
Publikováno v:
Blood. 86:557-571
Antisense oligonucleotide to the translation initiation sequence of human c-mpI reduced the proliferation of human CD34+ bone marrow cells in response to interleukin-3 (IL-3) alone or to the combination of IL-3 and thrombopoietin (TPO). To investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81fd7c1eab7542f7f89040f044e56e73
https://doi.org/10.1182/blood.v86.2.557.bloodjournal862557
https://doi.org/10.1182/blood.v86.2.557.bloodjournal862557
Autor:
Janice S. Valletta, William C. Mobley, Ahmad Salehi, Chun Fai Lai, John D. Cooper, Jean Dominique Delcroix, Charles L. Howe, Chenbiao Wu, Pavel V. Belichenko
Nerve growth factor (NGF) activates TrkA to trigger signaling events that promote the survival, differentiation and maintenance of neurons. The mechanism(s) that controls the retrograde transport of the NGF signal from axon terminals to neuron cell b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b991e5682c177fab585b3fc1a1f7f492
https://doi.org/10.1016/s0079-6123(03)46001-9
https://doi.org/10.1016/s0079-6123(03)46001-9
Autor:
Jean-Dominique, Delcroix, Janice, Valletta, Chenbiao, Wu, Charles L, Howe, Chun-Fai, Lai, John D, Cooper, Pavel V, Belichenko, Ahmad, Salehi, William C, Mobley
Publikováno v:
Progress in brain research. 146
Nerve growth factor (NGF) activates TrkA to trigger signaling events that promote the survival, differentiation and maintenance of neurons. The mechanism(s) that controls the retrograde transport of the NGF signal from axon terminals to neuron cell b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12fabd10bfaa9a6bfb36b473eb4bf34a
https://pubmed.ncbi.nlm.nih.gov/14699953
https://pubmed.ncbi.nlm.nih.gov/14699953
We investigated a role for endogenous Rap1, a small monomeric GTP-binding protein of the Ras family, in nerve growth factor (NGF) signaling in PC12 cells. Although both epidermal growth factor (EGF) and NGF caused transient activation of Ras, only NG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8cc8a0da1fc673ac9f76be9d2e76b5
https://europepmc.org/articles/PMC6762651/
https://europepmc.org/articles/PMC6762651/