Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Chun Y, Gao"'
Autor:
Ales Cvekl, Qing Xie, Rebecca McGreal, Chun Y. Gao, Lixing W. Reneker, Raven Harris, Linda S. Musil, Wei Liu
Fibroblast growth factor (FGF) signaling regulates a multitude of cellular processes, including cell proliferation, survival, migration, and differentiation. In the vertebrate lens, FGF signaling regulates fiber cell differentiation characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f0e9ce8f328be61969193a7094ead
https://europepmc.org/articles/PMC4759173/
https://europepmc.org/articles/PMC4759173/
Autor:
Chun Y. Gao, Patricia M. Zerfas, Nancy S. Longo, Fred Fan, Xuelian Tao, Victoria Hoffmann, Peter E. Lipsky
Publikováno v:
Arthritis & Rheumatism. 58:1774-1783
Extracts of the Chinese antirheumatic herbal remedy Tripterygium wilfordii Hook F (TWHF) have been shown to be of therapeutic benefit in patients with a variety of autoimmune and inflammatory diseases, including rheumatoid arthritis (RA), systemic lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614313a4dda50d92005876dd446870fb
https://doi.org/10.1002/art.23513
https://doi.org/10.1002/art.23513
Publikováno v:
Journal of Cell Science. 117:4089-4098
Recent studies have shown that Cdk5, a member of the cyclin-dependent-kinase family, regulates adhesion and migration in a mouse corneal epithelial cell line. Here, we extend these findings to corneal wound healing in vivo and examine the mechanism l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7a4655d8ca45a148f342c5190a2931
https://doi.org/10.1242/jcs.01271
https://doi.org/10.1242/jcs.01271
Publikováno v:
Retinal Degenerative Diseases ISBN: 9781461432081
LMAN1 is a type I transmembrane protein that selectively transports its cargo proteins from ER to ER-Golgi intermediate compartment (ERGIC) and Golgi. Lman1 is a direct target of the transcription factor NRL in mouse retina. Therefore, we examined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9f75c1babef461622a0708be793995
https://doi.org/10.1007/978-1-4614-3209-8_50
https://doi.org/10.1007/978-1-4614-3209-8_50
Autor:
Chun Y. Gao, Peggy S. Zelenka
Publikováno v:
BioEssays. 19:307-315
Cyclin-dependent kinases and their regulatory subunits, the cyclins, are known to regulate progression through the cell cycle. Yet these same proteins are often expressed in non-cycling, differentiated cells. This review surveys the available informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6389205eb0f5428d96282ac36e33bc15
https://doi.org/10.1002/bies.950190408
https://doi.org/10.1002/bies.950190408
Publikováno v:
Developmental Genetics. 20:267-275
We have investigated the expression of Cdk5 and its regulatory subunit, p35, in the developing rat lens from embryonic day 16 (E16) to postnatal day 8 (P8). Reverse transcription and polymerase chain reaction (RT/PCR) detected Cdk5 and p35 mRNA expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401b73059a4edac55d1c13efde224b31
https://doi.org/10.1002/(sici)1520-6408(1997)20:3<267::aid-dvg9>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1997)20:3<267::aid-dvg9>3.0.co
Autor:
Parthasarathy, Arpitha, Chun Y, Gao, Brajendra K, Tripathi, Senthil, Saravanamuthu, Peggy, Zelenka
Publikováno v:
Molecular Vision
Purpose Although cyclin-dependent kinase 5 (Cdk5) inhibits the formation of junctions containing N-cadherin, the effect of Cdk5 on junctions containing E-cadherin is less clear. The present study investigates the functional significance of Cdk5 in fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a95b4569b80a76de9f6970e480ef4d3a
https://pubmed.ncbi.nlm.nih.gov/23401660
https://pubmed.ncbi.nlm.nih.gov/23401660
The non-receptor tyrosine kinase Src is a critical regulator of cytoskeletal contraction, cell adhesion, and migration. In normal cells, Src activity is stringently controlled by Csk-dependent phosphorylation of Src(Y530), and by Cullin-5-dependent u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316b170e303644130bd899f122ea2ff5
https://europepmc.org/articles/PMC3167940/
https://europepmc.org/articles/PMC3167940/
Publikováno v:
Journal of Visualized Experiments : JoVE
The anterior surface of the ocular lens is covered by a monolayer of epithelial cells, which proliferate in an annular zone underlying the ciliary body. Following division, these cells migrate posteriorly, where FGF diffusing from the retina induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ca721b64fc5e4c85e28580bb151186
https://pubmed.ncbi.nlm.nih.gov/19773734
https://pubmed.ncbi.nlm.nih.gov/19773734
Previous studies of the developing lens have shown that Notch signaling regulates differentiation of lens fiber cells by maintaining a proliferating precursor pool in the anterior epithelium. However, whether Notch signaling is further required after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4c6a9c8148271c79d960ba60b23caa
https://europepmc.org/articles/PMC2730671/
https://europepmc.org/articles/PMC2730671/