Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Chun Wei Tung"'
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Data scarcity is one of the most critical issues impeding the development of prediction models for chemical effects. Multitask learning algorithms leveraging knowledge from relevant tasks showed potential for dealing with tasks with limited
Externí odkaz:
https://doaj.org/article/9fe338ca872f498885678468e894a709
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 3, Pp 1023-1035 (2024)
In silico toxicogenomics methods are resource- and time-efficient approaches for inferring chemical–protein–disease associations with potential mechanism information for exploring toxicological effects. However, current in silico toxicogenomics s
Externí odkaz:
https://doaj.org/article/da47d03071ba45bc999ce637d3ca8b90
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-10 (2024)
Abstract Background Fipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that exposure to FPN might induce unexpected adverse effects in the liver, reproductive, and ner
Externí odkaz:
https://doaj.org/article/0091c435acca43d18373c24cb47fe076
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract The drug discovery of G protein-coupled receptors (GPCRs) superfamily using computational models is often limited by the availability of protein three-dimensional (3D) structures and chemicals with experimentally measured bioactivities. Orph
Externí odkaz:
https://doaj.org/article/253a48971ddb440ca47f20d19d23b992
Autor:
Hsin-Pei Weng, Chiao-Hsu Ke, Chun-Wei Tung, Akiyoshi Tani, Chia-Chi Wang, Wen-Yuan Yang, Yu-Shan Wang, Winston Han, Chi-Hsun Liao, Hirotaka Tomiyasu, Chen-Si Lin
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-22 (2023)
Abstract Background Tumor-derived extracellular vesicles (EVs) have been proposed as the essential mediator between host immunity and cancer development. These EVs conduct cellular communication to facilitate tumor growth, enable invasion and metasta
Externí odkaz:
https://doaj.org/article/25558b396a7f4dce8cfe5d511c7a8803
Autor:
Wan-Chi Hsiao, Guang-Hao Niu, Chen-Fu Lo, Jing-Ya Wang, Ya-Hui Chi, Wei-Cheng Huang, Chun-Wei Tung, Ping-Jyun Sung, Lun Kelvin Tsou, Mingzi M. Zhang
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Natural products are important sources of therapeutic agents and useful drug discovery tools. The fused macrocycles and multiple stereocenters of briarane-type diterpenoids pose a major challenge to total synthesis and efforts to characteriz
Externí odkaz:
https://doaj.org/article/64529d9078fa4ba991901ba2e168cd74
Autor:
Chia-Chi Wang, Yu-Ting Hung, Che-Yu Chou, Shih-Ling Hsuan, Zeng-Weng Chen, Pei-Yu Chang, Tong-Rong Jan, Chun-Wei Tung
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-10 (2023)
Abstract Antimicrobial resistance (AMR) is a global health issue and surveillance of AMR can be useful for understanding AMR trends and planning intervention strategies. Salmonella, widely distributed in food-producing animals, has been considered th
Externí odkaz:
https://doaj.org/article/0d106dffefbb40368a1fbe2639b7758a
Autor:
Ping-Hsun Wu, Yu-Fang Tseng, Wangta Liu, Yun-Shiuan Chuang, Chi-Jung Tai, Chun-Wei Tung, Kean-Yee Lai, Mei-Chuan Kuo, Yi-Wen Chiu, Shang-Jyh Hwang, Wei-Chun Hung, Yi-Ting Lin
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 148 (2024)
Indole-3-acetic acid (IAA), a protein-bound uremic toxin resulting from gut microbiota-driven tryptophan metabolism, increases in hemodialysis (HD) patients. IAA may induce endothelial dysfunction, inflammation, and oxidative stress, elevating cardio
Externí odkaz:
https://doaj.org/article/d11a01d8d8de4387a1c24f0cf7053f61
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S10, Pp 1-14 (2022)
Abstract Background The placental barrier protects the fetus from exposure to some toxicants and is vital for drug development and risk assessment of environmental chemicals. However, in vivo experiments for assessing the placental barrier permeabili
Externí odkaz:
https://doaj.org/article/99c294dfbeae43218402f033d5e6fda5
Publikováno v:
PeerJ, Vol 8, p e9562 (2020)
Background The measurement of human fetal-maternal blood concentration ratio (logFM) of chemicals is critical for the risk assessment of chemical-induced developmental toxicity. While a few in vitro and ex vivo experimental methods were developed for
Externí odkaz:
https://doaj.org/article/44b21ac692ec42edbe962f4927103724