Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Chun Tao Lei"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 2, Pp 451-460 (2018)
Background/Aims: Renal tubular epithelial cells and fibroblasts are the main sources of myofibroblasts, and these cells produce the extracellular matrix during tubulointerstitial fibrosis (TIF). Histone deacetylases (HDAC) inhibitors exert an antifib
Externí odkaz:
https://doaj.org/article/3bb95272e8004ba8b05077c8a7cd1deb
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 1, Pp 281-294 (2017)
Background: Protein Kinase C-α (PKC-α) and epidermal growth factor receptor (EGFR) are both involved in diabetic kidney disease; however, the connection between these two proteins during high glucose-induced podocyte injury remains uncertain. Metho
Externí odkaz:
https://doaj.org/article/86b1fe4034824e8d9c9c4347f48e781e
Publikováno v:
Kidney & Blood Pressure Research, Vol 41, Iss 5, Pp 643-653 (2016)
Background/Aims: Caspases, an evolutionary conserved family of aspartate-specific cystein proteases, play pivotal roles in apoptotic and inflammatory signaling. Thus far, 14 mammalian caspases are identified and categorized into 3 distinct sub-types:
Externí odkaz:
https://doaj.org/article/6d01f9a723034f6b96a9c53f0517768f
Autor:
Meng-Ran, Li, Chun-Tao, Lei, Hui, Tang, Xing-Jie, Yin, Zhe, Hao, Yang, Qiu, Ya-Ru, Xie, Jie-Yu, Zeng, Hua, Su, Chun, Zhang
Publikováno v:
International Journal of Biological Sciences. 18:1896-1911
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Interleukin-6 (IL-6) is a pleiotropic cytokine that not only regulates the immune and inflammatory response but also affects hematopoiesis, metabolism, and organ development. IL-6 can simultaneously elicit distinct or even contradictory physiopatholo
Externí odkaz:
https://doaj.org/article/a50ff3a1bd4840f18cad4bd4f5fdec2c
Autor:
Hui Chen, Ying-Chuan Fan, Qi-Hong He, Xiao-Yun Wu, Min Wei, June E. Eichner, Bradley K. Farris, P. Lloyd Hildebrand, Chun-Tao Lei, Shu-Hua Wu, Jing-Yun Yang
Publikováno v:
International Journal of Ophthalmology, Vol 7, Iss 1, Pp 139-144 (2014)
AIM:To study the trends of major causes of visual impairment (VI) in adults in Sichuan, China and evaluate the effect of aging on the trends.METHODS: We used data from the National Sample Survey on Disabilities (NSSD) in Sichuan province conducted in
Externí odkaz:
https://doaj.org/article/dc38174f036540c3bd8dd0af2ad50291
Autor:
Jing Liu, Xiao Hui Wang, Yang Qiu, Chun Zhang, Junwu Dong, Zheng Zhao, Can Tu, Xiaoping Miao, Jianbo Tian, Fei Xiong, Chun-Tao Lei, Hui Tang, Xin Sun
Publikováno v:
Seminars in Dialysis
Introduction Maintenance hemodialysis (MHD) patients are highly threatened in the novel coronavirus disease 2019 (COVID‐19) pandemic, but evidence of risk factors for mortality in this population is still lacking. Methods We followed outcomes of th
Publikováno v:
Theranostics
Rationale: Acute kidney injury (AKI) is a serious clinical emergency with an acute onset, rapid progression, and poor prognosis. Recent evidence suggests that AKI is accompanied by significant metabolic abnormalities, including alterations in lipid m
Autor:
Fang-Fang He, Dian Bao, Hua Su, Hui Tang, Chen Ye, Chun Zhang, Chun-Tao Lei, Hans-Peter Hammes, Jihong Lin, Wei Xiong
Publikováno v:
International Journal of Biological Sciences
Rationale: Focal segmental glomerulosclerosis (FSGS) is characterized by the dysfunction of “post-mitotic” podocytes. The reentry of podocytes in the cell cycle will ultimately result in cell death. Mitotic arrest deficient 2-like protein 2 (MAD2
Autor:
Jian Bo Tian, Li Liu, Wen Li Chen, Chun Zhang, Ming Shi, Fei Xiong, Chun Tao Lei, Jing Liu, Jun Wu Dong, Dan Luo, Hui Tang, Xiaoping Miao, Can Tu, Xiao Hui Wang
Publikováno v:
J Am Soc Nephrol
Background Reports indicate that those most vulnerable to developing severe coronavirus disease 2019 (COVID-19) are older adults and those with underlying illnesses, such as diabetes mellitus, hypertension, or cardiovascular disease, which are common