Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chun Sik Kwak"'
Publikováno v:
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 20:699-702
Objective During peritoneal dialysis, the peritoneum is exposed to waste products, including urea. Urea forms cyanate spontaneously at body temperature and pH, and cyanate carbamylates amino acids, peptides, and proteins. Cyanate may contribute to pe
Autor:
Ik Jae Moon, Chun Sik Kwak, Je Ho Lee, Alan D. Schreiber, Jong-Gu Park, Kyu Sam Choi, Young Ik Lee
Publikováno v:
Biochemical Journal. 346:295-303
Systematic secondary structure simulation of a target mRNA sequence is shown to be effective for locating a good anti-sense target site. Multiple selected anti-sense sequences were placed in a single molecule. The anti-sense oligonucleotide (oligo) w
Publikováno v:
Renal Failure. 22:809-814
During advanced renal failure, and particularly in patients with end-stage renal disease, proteins are carbamylated as a result of a reaction with cyanate. If the carbamylation of proteins adversely alters their biologic activities and structures, th
Autor:
Chun-Sik Kwak, Kyo-Cheol Mun
Publikováno v:
Experimental & Molecular Medicine. 28:125-130
The involvement of bile acids in hepatic damage under cholestasis and the effect of lowering bile acid level through the inhibition of microsomal 3- hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by lovastatin was studied. Rats were divided into fi
Publikováno v:
Annals of the New York Academy of Sciences. 765:86-97
Glutamate (GLU) is a neurotransmitter. Massive release of GLU and glycine (GLY) into the brain's extracellular space may be triggered by ischemia, and may result in acute neuronal lysis or delayed neuronal death. The aim of this study was to evaluate
Autor:
Chun-Sik Kwak, E.J. Chang, Seungyeup Han, H.J. Choi, Kyo-Cheol Mun, Hyun Chul Kim, Sung Bae Park
Publikováno v:
Transplantation proceedings. 38(7)
Introduction The immunosuppressive agent cyclosporine (CsA) is widely used to treat allograft rejection and various autoimmune disorders. A major limiting factor in the use of CsA is chronic nephrotoxicity. The pathogenesis of CsA-induced nephrotoxic
Autor:
H.-G Lee, Chun-Sik Kwak, Yeo Hyang Kim, Sung Bae Park, Tae Hee Lee, E.J. Chang, Kyo-Cheol Mun, Hyun Chul Kim, Sang-Hyon Kim
Publikováno v:
Transplantation proceedings. 35(1)
Publikováno v:
Transplantation proceedings. 32(7)
Autor:
N.H. Lee, Sung Bae Park, S.I. Nam, E.J. Chang, Seungyeup Han, Chun-Sik Kwak, Kyo-Cheol Mun, Hyun Chul Kim, H.J. Choi
Publikováno v:
Transplantation Proceedings. 38:2214-2215
Objectives The damage induced by oxygen free radicals (OFRs) is caused by an imbalance of the production of versus the antioxidant defenses against OFRs. Methods To understand hepatic damage induced by oxygen free radicals after hepatectomy in rats,
Publikováno v:
Journal of Korean Medical Science
To determine whether oxygen free radicals are responsible for the pathogenesis of the cholestasis induced by ligation of common bile duct (CBD) variables which reflect the hepatic function in the serum, the amount of superoxide radical production, an