Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chun Sheng Ruan"'
Autor:
Xia Hu, Zhao-Lan Hu, Zheng Li, Chun-Sheng Ruan, Wen-Ying Qiu, Aihua Pan, Chang-Qi Li, Yan Cai, Lu Shen, Yaping Chu, Bei-Sha Tang, Huaibin Cai, Xin-Fu Zhou, Chao Ma, Xiao-Xin Yan
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
Genetic variations in the vacuolar protein sorting 10 protein (Vps10p) family have been linked to Alzheimer’s disease (AD). Here we demonstrate deposition of fragments from the Vps10p member sortilin at senile plaques (SPs) in aged and AD human cer
Externí odkaz:
https://doaj.org/article/60ee654d081d45159302a0663d054b15
ProBDNF/p75NTR/sortilin pathway is activated in peripheral blood of patients with alcohol dependence
Publikováno v:
Translational Psychiatry, Vol 7, Iss 11, Pp 1-10 (2018)
Translational Psychiatry
Translational Psychiatry
Alcohol dependence is a worldwide problem with a great social and economic burden in many countries. A number of studies have suggested that BDNF (mature BDNF) and its precursor (proBDNF) play important roles in the alcohol dependence. However, what
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666b140c4163928a6b7cf62e524956ce
http://link.springer.com/article/10.1038/s41398-017-0015-4
http://link.springer.com/article/10.1038/s41398-017-0015-4
Autor:
Larisa Bobrovskaya, Chun-Sheng Ruan, Yue-Qin Zeng, Xin-Fu Zhou, Jia Liu, Khalil Saadipour, Miao Yang, Hong Liao, Yan-Jiang Wang
Publikováno v:
Experimental Neurology. 299:75-85
Amyloid plaque is one of the hallmarks of Alzheimer's disease (AD). The key component beta-amyloid (Aβ) is generated via proteolytic processing of amyloid precursor protein (APP). Sortilin (encoded by the gene Sort1) is a vacuolar protein sorting 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26263b9ca17017cd663a98dc8fe2caa6
https://doi.org/10.1016/j.expneurol.2017.10.018
https://doi.org/10.1016/j.expneurol.2017.10.018
Publikováno v:
Experimental Neurology. 281:99-108
Exposure to stressful life events plays a central role in the development of mood disorders in vulnerable individuals. However, the mechanisms that link mood disorders to stress are poorly understood. Brain-derived neurotrophic factor (BDNF) has long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36065d2f2e6f6efa8c9ed63cc051b543
https://doi.org/10.1016/j.expneurol.2016.04.015
https://doi.org/10.1016/j.expneurol.2016.04.015
Autor:
Yangli Xie, Prem P. Dwivedi, Jiake Xu, Lin Chen, Chun-Sheng Ruan, Vicki Rosen, Bruce K. Foster, Ke-Ming Chen, Shek Man Chim, Mohammadhossein Hassanshahi, Cory J. Xian, Rosa Chung, Vincent Kuek, Yuwen Su, Xin-Fu Zhou
Publikováno v:
Journal of Bone and Mineral Research. 31:1258-1274
Injured growth plate is often repaired by bony tissue causing bone growth defects, for which the mechanisms remain unclear. Because neurotrophins have been implicated in bone fracture repair, here we investigated their potential roles in growth plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97381b16ca6804a2b93d127945536232
https://doi.org/10.1002/jbmr.2786
https://doi.org/10.1002/jbmr.2786
Chronic stress has been known as a main cause for human mood disorders. The understanding of the pathogenesis of the mood disorders are primarily based on the usage of animal models.Low reproducibility and complicacy of production are commonly known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d05f104cc1ef4c03a2142f83f9c1b1
https://hdl.handle.net/11541.2/137299
https://hdl.handle.net/11541.2/137299
usc Alzheimer’s disease (AD) and anxiety are two concurrent disorders often co-existing in older adults. Interestingly, women are more likely to experience anxiety than men in both general population and AD. To date, the mechanisms underlying the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbb3737e173d265da38422e68d00e67
https://hdl.handle.net/11541.2/137468
https://hdl.handle.net/11541.2/137468
Autor:
Yin-Yin Bai, Ting-Hua Wang, Chun-Sheng Ruan, Yue-Qing Zeng, Xin-Fu Zhou, Li Zhou, Jia-yi Li, Hong Liao, Larisa Bobrovskaya, Chang-Fu Tian, Zhi-Long Kang, Dennis Liu, Chun-Rui Yang
Chronic exposure to stressful environment is a key risk factor contributing to the development of depression. However, the mechanisms involved in this process are still unclear. Brain-derived neurotropic factor (BDNF) has long been investigated for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4e7b0f779a2241a734bf65262cb530
https://europepmc.org/articles/PMC5061880/
https://europepmc.org/articles/PMC5061880/
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e5d726f9014cbffa30c46b1990b19ee
https://doi.org/10.1016/j.jalz.2016.06.883
https://doi.org/10.1016/j.jalz.2016.06.883
Publikováno v:
Neurotoxicity research. 31(2)
Foraging behavior is a species-specific behavior which is considered to involve the decision making and higher cognitive functions. We previously established a novel method to detect the foraging behavior in chronic unpredictable mild stress (CUMS)-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddab8ecf6a5996272bc2b0ca7f7edf7b
https://pubmed.ncbi.nlm.nih.gov/27957676
https://pubmed.ncbi.nlm.nih.gov/27957676