Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Chun Ong"'
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
PDF file - 2.9MB, In-vitro kinase assay, Histology, Cell proliferation, MANOVA analysis for genomic correlates of drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ecb3048e6ff5affcb194a51978b5d1
https://doi.org/10.1158/1535-7163.22497421
https://doi.org/10.1158/1535-7163.22497421
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
Dysregulation of the PI3K/mTOR pathway, either through amplifications, deletions, or as a direct result of mutations, has been closely linked to the development and progression of a wide range of cancers. Moreover, this pathway activation is a poor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389efae3908c20bd53e37aa050195e71
https://doi.org/10.1158/1535-7163.c.6535609
https://doi.org/10.1158/1535-7163.c.6535609
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
PDF file - 663K, Ambit kinome tree, Cell proliferation data, Pharmacokinetics, Body weight changes in PC3 efficacy study, Active vessel stain in COLO-205 efficacy study, MV4-11 efficacy model, Drug sensitivity profiling and correlation to mutation st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407e7e397fec9712aed4f01696117bc4
https://doi.org/10.1158/1535-7163.22497424
https://doi.org/10.1158/1535-7163.22497424
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
XLS file - 167K, Table 1: Cell line drug sensitivity data for SB2343 and mutations in cancer genes. Table 2: Results from MANOVA analysis of cancer genes as modifiers of drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794bb76ff68be2e6a52cec2e5c03efb5
https://doi.org/10.1158/1535-7163.22497418
https://doi.org/10.1158/1535-7163.22497418
Autor:
Xiao Jun Wang, Yi-Ho Wang, Matthew Jian Chun Ong, Christina Gkitzia, Shui Yen Soh, William Ying Khee Hwang
Publikováno v:
ClinicoEconomics and Outcomes Research.
Xiao Jun Wang,1 Yi-Ho Wang,2 Matthew Jian Chun Ong,1 Christina Gkitzia,3 Shui Yen Soh,4 William Ying Khee Hwang5â 7 1Novartis Singapore Pte Ltd, Singapore; 2Novartis Asia Pacific Pharmaceuticals Pte Ltd, Singapore; 3Novartis Pharma AG, Basel, Sw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e677a0da9377d74d0d6dae3ec37a73c
https://www.dovepress.com/cost-effectiveness-and-budget-impact-analyses-of-tisagenlecleucel-in-p-peer-reviewed-fulltext-article-CEOR
https://www.dovepress.com/cost-effectiveness-and-budget-impact-analyses-of-tisagenlecleucel-in-p-peer-reviewed-fulltext-article-CEOR
Autor:
Ximei Huang, Sha Huang, Lai Chun Ong, Jason Chu-Shern Lim, Rebecca Joan Mary Hurst, Annals Tatenda Mushunje, Paul Thomas Matsudaira, Jongyoon Han, Peter Rainer Preiser
Publikováno v:
mSphere, Vol 1, Iss 1 (2016)
ABSTRACT Infections by malaria parasites can lead to very different clinical outcomes, ranging from mild symptoms to death. Differences in the ability of the spleen to deal with the infected red blood cells (iRBCs) are linked to differences in virule
Externí odkaz:
https://doaj.org/article/3ed175b2c96241368c208a548f0d23ac
Autor:
Yilong Fu, Lai-Chun Ong, Sudhir H Ranganath, Lin Zheng, Irene Kee, Wenbo Zhan, Sidney Yu, Pierce K H Chow, Chi-Hwa Wang
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148123 (2016)
Early diagnosis of low grade glioma has been a challenge to clinicians. Positron Emission Tomography (PET) using 18F-FDG as a radio-tracer has limited utility in this area because of the high background in normal brain tissue. Other radiotracers such
Externí odkaz:
https://doaj.org/article/c7f968ceacb04fb6a7cbdeb1150b77df
Autor:
Wan Chin Liaw, Janice M. Fletcher, Peter Sharp, Matilda R. Jackson, Xiaodan Ding, Chun Ong, Xenia Kaidonis, Enzo Ranieri, Sharon Byers, Ainslie L.K. Derrick-Roberts
Publikováno v:
Molecular Genetics and Metabolism. 131:197-205
The cause of neurodegeneration in MPS mouse models is the focus of much debate and what the underlying cause of disease pathology in MPS mice is. The timing of development of pathology and when this can be reversed or impacted is the key to developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d807843dcbe6d556c2ee4f944e700636
https://doi.org/10.1016/j.ymgme.2020.07.006
https://doi.org/10.1016/j.ymgme.2020.07.006
Autor:
Hock Chun Ong, Joshua T. Y. Tse
Publikováno v:
Physical Review B. 104
Surface lattice resonance (SLR) is the collective excitation of nanoparticle resonances arising from the hybridization between localized surface plasmons (LSPs) and propagating Rayleigh anomalies (RAs). When comparing with the corresponding LSPs, SLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9a0320f7684cec3b57c5e8c3aec17b
https://doi.org/10.1103/physrevb.104.125442
https://doi.org/10.1103/physrevb.104.125442
Autor:
Ainslie Derrick-Roberts, Xenia Kaidonis, Matilda R. Jackson, Wan Chin Liaw, XiaoDan Ding, Chun Ong, Enzo Ranieri, Peter Sharp, Janice Fletcher, Sharon Byers
Publikováno v:
Molecular Genetics and Metabolism. 135:114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8298cdfbef973f2e7b01e79cc25e30fa
https://doi.org/10.1016/j.ymgme.2021.12.011
https://doi.org/10.1016/j.ymgme.2021.12.011