Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Chun Ling Jung"'
Autor:
Amy Zhou, Tim Kong, Jared S. Fowles, Chun‐Ling Jung, Maggie J. Allen, Daniel A. C. Fisher, Mary Fulbright, Elizabeta Nemeth, Tomas Ganz, Stephen T. Oh
Publikováno v:
British Journal of Haematology. 197
Autor:
Brian J. Van Lenten, Alan C. Wagner, Chun-Ling Jung, Piotr Ruchala, Alan J. Waring, Robert I. Lehrer, Andrew D. Watson, Susan Hama, Mohamad Navab, G.M. Anantharamaiah, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 11, Pp 2302-2311 (2008)
4F is an anti-inflammatory, apolipoprotein A-I (apoA-I)-mimetic peptide that is active in vivo at nanomolar concentrations in the presence of a large molar excess of apoA-I. Physiologic concentrations (∼35 μM) of human apoA-I did not inhibit the p
Externí odkaz:
https://doaj.org/article/52f74bd84e904fa99c792f2fe031fac0
Autor:
Charles Kung, Carlo Brugnara, Maria Teresa Valenti, Sebastien Ronseaux, Iana Iatcenko, Tomas Ganz, Anne Janin, Penelope A. Kosinski, Rohini Narayanaswamy, Leonardo Salviati, Achille Iolascon, Francesca Carlomagno, Shaoxia Yu, Giorgia Federico, Enrica Federti, Lucia De Franceschi, Chun-Ling Jung, Alessandro Matte, Roberta Russo, Francesco Michelangelo Turrini, Elisabetta Beneduce, Christophe Leboeuf, Maria Andrea Desbats, Lenny Dang
Publikováno v:
The Journal of clinical investigation
The Journal of clinical investigation, 2021, 131 (10), pp.e144206. ⟨10.1172/jci144206⟩
J Clin Invest
The Journal of clinical investigation, 2021, 131 (10), pp.e144206. ⟨10.1172/jci144206⟩
J Clin Invest
International audience; Anemia in β-thalassemia is related to ineffective erythropoiesis and reduced red cell survival. Excess free heme and accumulation of unpaired α-globin chains impose substantial oxidative stress on β-thalassemic erythroblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41cc272a7692f282ce5e5195c770def
http://hdl.handle.net/11577/3443135
http://hdl.handle.net/11577/3443135
Autor:
Nannette Y Yount, Samuel E Cohen, Deborah Kupferwasser, Alan J Waring, Piotr Ruchala, Shantanu Sharma, Karlman Wasserman, Chun-Ling Jung, Michael R Yeaman
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26727 (2011)
Structure-mechanism relationships are key determinants of host defense peptide efficacy. These relationships are influenced by anatomic, physiologic and microbiologic contexts. Structure-mechanism correlates were assessed for the synthetic peptide RP
Externí odkaz:
https://doaj.org/article/240df7e3efd54b47980581b201b299ff
Autor:
Ewa D Micewicz, Amy L Cole, Chun-Ling Jung, Hai Luong, Martin L Phillips, Pratikhya Pratikhya, Shantanu Sharma, Alan J Waring, Alexander M Cole, Piotr Ruchala
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14360 (2010)
Griffithsin, a 121-residue protein isolated from a red algal Griffithsia sp., binds high mannose N-linked glycans of virus surface glycoproteins with extremely high affinity, a property that allows it to prevent the entry of primary isolates and labo
Externí odkaz:
https://doaj.org/article/f4f5df1fd73a42ecb0821696d892a5c3
Autor:
Piotr Ruchala, Mohamad Navab, Chun-Ling Jung, Susan Hama-Levy, Ewa D Micewicz, Hai Luong, Jonathan E Reyles, Shantanu Sharma, Alan J Waring, Alan M Fogelman, Robert I Lehrer
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10181 (2010)
Many gram-positive bacteria produce pore-forming exotoxins that contain a highly conserved, 12-residue domain (ECTGLAWEWWRT) that binds cholesterol. This domain is usually flanked N-terminally by arginine and C-terminally by valine. We used this 14-r
Externí odkaz:
https://doaj.org/article/d344662ec3ae4b19a7b61387f0eee6f0
Autor:
Frans J Walther, Alan J Waring, Jose M Hernandez-Juviel, Larry M Gordon, Zhengdong Wang, Chun-Ling Jung, Piotr Ruchala, Andrew P Clark, Wesley M Smith, Shantanu Sharma, Robert H Notter
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8672 (2010)
Surfactant protein B (SP-B; 79 residues) belongs to the saposin protein superfamily, and plays functional roles in lung surfactant. The disulfide cross-linked, N- and C-terminal domains of SP-B have been theoretically predicted to fold as charged, am
Externí odkaz:
https://doaj.org/article/f0da13feaef84fc5adb66dd3f109e5d0
Dynamic surface activity of a fully synthetic phospholipase-resistant lipid/peptide lung surfactant.
Autor:
Frans J Walther, Alan J Waring, Jose M Hernandez-Juviel, Larry M Gordon, Adrian L Schwan, Chun-Ling Jung, Yusuo Chang, Zhengdong Wang, Robert H Notter
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1039 (2007)
This study examines the surface activity and resistance to phospholipase degradation of a fully-synthetic lung surfactant containing a novel diether phosphonolipid (DEPN-8) plus a 34 amino acid peptide (Mini-B) related to native surfactant protein (S
Externí odkaz:
https://doaj.org/article/c1c6394b58a846bca8d3586f615ca3c7
Autor:
Asim Dasgupta, Christopher Sundberg, Samuel W. French, Ekambaram Ganapathy, Vaithilingaraja Arumugaswami, Rana Riahi, Piotr Ruchala, Nicole M. Wheatley, Hao Shao, Ronik Khachatoorian, Jason E. Gestwicki, Chun-Ling Jung
Publikováno v:
International Journal of Antimicrobial Agents. 47:289-296
The human molecular chaperones heat shock protein 70 (Hsp70) and heat shock cognate protein 70 (Hsc70) bind to the hepatitis C viral nonstructural protein 5A (NS5A) and regulate its activity. Specifically, Hsp70 is involved in NS5A-augmented internal
Autor:
Alan J. Waring, Asim Dasgupta, Ronik Khachatoorian, Chun-Ling Jung, Christopher Sundberg, Piotr Ruchala, Ekambaram Ganapathy, Samuel W. French, Vaithilingaraja Arumugaswami, Nicole M. Wheatley
Publikováno v:
Khachatoorian, Ronik; Ruchala, Piotr; Waring, Alan; Jung, Chun-Ling; Ganapathy, Ekambaram; Wheatley, Nicole; et al.(2014). Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology, 475, 46-55. UC Office of the President: Multicampus Research Programs and Initiatives (MRPI); a funding opportunity through UC Research Initiatives (UCRI). Retrieved from: http://www.escholarship.org/uc/item/91h66262
We previously identified the NS5A/HSP70 binding site to be a hairpin moiety at C-terminus of NS5A domain I and showed a corresponding cyclized polyarginine-tagged synthetic peptide (HCV4) significantly blocks virus production. Here, sequence comparis