Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Chun Jung Chen"'
NMDA receptor blockade attenuates Japanese encephalitis virus infection-induced microglia activation
Autor:
Cheng-Yi Chang, Chih-Cheng Wu, Chung-Yuh Tzeng, Jian-Ri Li, Yu-Fang Chen, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Chun-Jung Chen
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Neurodegeneration and neuroinflammation are key components in the pathogenesis of Japanese Encephalitis caused by Japanese Encephalitis Virus (JEV) infection. The N-methyl-D-aspartate (NMDA)-type glutamate receptor displays excitatory neurot
Externí odkaz:
https://doaj.org/article/2d61bd84790742fa947dee55c9ee68e9
Autor:
Kun-Lin Yeh, Sheng-Wen Wu, Chen-Yu Chiang, Chun-Jung Chen, Wen-Ying Chen, Ching-Chi Tseng, Yu-Hsiang Kuan, Chi-Chung Chou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117346- (2024)
Oxidative damage contributes to age-related macular degeneration. Irigenin possesses diverse pharmacologic properties, including antioxidative and antiapoptotic effects. Our in vivo experiments indicated that irigenin mitigates UVB-induced histopatho
Externí odkaz:
https://doaj.org/article/8d65e125f6e2418daf514be82d527a84
Autor:
Wesley Tien Chiang, Yao-Kai Chang, Wei-Han Hui, Shu-Wei Chang, Chen-Yi Liao, Yi-Chuan Chang, Chun-Jung Chen, Wei-Chen Wang, Chien-Chen Lai, Chun-Hsiung Wang, Siou-Ying Luo, Ya-Ping Huang, Shan-Ho Chou, Tzyy-Leng Horng, Ming-Hon Hou, Stephen P. Muench, Ren-Shiang Chen, Ming-Daw Tsai, Nien-Jen Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The K+ uptake system KtrAB is essential for bacterial survival in low K+ environments. The activity of KtrAB is regulated by nucleotides and Na+. Previous studies proposed a putative gating mechanism of KtrB regulated by KtrA upon binding to
Externí odkaz:
https://doaj.org/article/22979af054c246cc93ea86e4f5a579c0
Autor:
Yin-Cheng Hsieh, Hong-Hsiang Guan, Chien-Chih Lin, Teng-Yi Huang, Phimonphan Chuankhayan, Nai-Chi Chen, Nan-Hsuan Wang, Pu-Ling Hu, Yi-Chien Tsai, Yen-Chieh Huang, Masato Yoshimura, Pei-Ju Lin, Yih-Huang Hsieh, Chun-Jung Chen
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2130-2150 (2024)
Externí odkaz:
https://doaj.org/article/8adb9c36a5a542e583336e37a8100352
Autor:
Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Chun Jung Chen, Steven J Halvorson, Nadim J Ajami, Corey W Hecksel, Jody L Swain, Connie Wong, Christopher S Sullivan, Janet S Butel
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003912 (2014)
Effects of polyomavirus SV40 microRNA on pathogenesis of viral infections in vivo are not known. Syrian golden hamsters are the small animal model for studies of SV40. We report here effects of SV40 microRNA and influence of the structure of the regu
Externí odkaz:
https://doaj.org/article/f88b107efd3e4e1d9e618e8a2097672c
Autor:
Yu-Li Lo, Ching-Yao Li, Tsui-Fen Chou, Ching-Ping Yang, Li-Ling Wu, Chun-Jung Chen, Yih-Hsin Chang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116660- (2024)
Pancreatic ductal adenocarcinoma (PDAC) has an extremely devastating nature with poor prognosis and increasing incidence, making it a formidable challenge in the global fight against cancer-related mortality. In this innovative preclinical investigat
Externí odkaz:
https://doaj.org/article/d2e23416c3de49658faa8ae2328aedf3
Autor:
Sruthi Thiraviam Saravanan, Jaysiva Ganesamurthi, Shen-Ming Chen, Tse-Wei Chen, Chun-Jung Chen, Keseven Lakshmanan, Partheeban Chinnamuthu, Xiaoheng Liu, Ramachandran Balaji
Publikováno v:
J, Vol 6, Iss 4, Pp 536-543 (2023)
Increasingly sophisticated techniques for falsifying and forging legal documents demand non-destructive and accurate analysis methods. Researchers have extensively investigated ink discrimination through an interdisciplinary analysis involving Raman
Externí odkaz:
https://doaj.org/article/e664d78d00704cd4932aa5a4518ac4c4
Autor:
Hung-Chieh Lu, Taichen Lin, Min Yee Ng, Chang-Wei Hsieh, Yi-Wen Liao, Chun-Cheng Chen, Cheng-Chia Yu, Chun-Jung Chen
Publikováno v:
Journal of Dental Sciences, Vol 18, Iss 2, Pp 666-673 (2023)
Background/purpose: :Both periodontal disease and diabetes mellitus (DM) are long-term inflammatory disorders that are highly prevalent and have a significant health impact. Inflammaging, a state of pre-aging and hyperinflammatory state has been ackn
Externí odkaz:
https://doaj.org/article/cf35421663f941d18ea62a52c9040260
Autor:
Ci-Wen Luo, Yu-Hsiang Kuan, Wen-Ying Chen, Chun-Jung Chen, Frank Cheau-Feng Lin, Stella Chin-Shaw Tsai
Publikováno v:
Epidemiology and Health, Vol 45 (2023)
OBJECTIVES This cohort study investigated the correlation between Parkinson’s disease (PD) risk and chronic obstructive pulmonary disease (COPD) risk under particulate matter with an aerodynamic diameter ≤2.5 μm (PM2.5) exposure. METHODS Data fr
Externí odkaz:
https://doaj.org/article/3a45e080148941618daa62c944bb65ae
Autor:
Nai-Chi Chen, Chun-Hsiung Wang, Masato Yoshimura, Yi-Qi Yeh, Hong-Hsiang Guan, Phimonphan Chuankhayan, Chien-Chih Lin, Pei-Ju Lin, Yen-Chieh Huang, Soichi Wakatsuki, Meng-Chiao Ho, Chun-Jung Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Viruses can cause Colony Collapse Disorder, leading to large losses of honeybee hives globally. In this study, the authors solve capsid structures of honeybee-infecting Lake Sinai viruses and identify distinct features, which advances understanding o
Externí odkaz:
https://doaj.org/article/f21c98a297944033a2fab46ed62b6422