Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Chun I. Yu"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103155- (2024)
Summary: Humanized mice, defined as mice with human immune systems, have become an emerging model to study human hematopoiesis, infectious disease, and cancer. Here, we describe the techniques to generate humanized NSGF6 mice using adult human CD34+
Externí odkaz:
https://doaj.org/article/cb4168375e2a454492a1e19975ce7d30
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109238- (2024)
Summary: Pre-clinical use of humanized mice transplanted with CD34+ hematopoietic stem and progenitor cells (HSPCs) is limited by insufficient engraftment with adult non-mobilized HSPCs. Here, we developed a novel immunodeficient mice based on NOD-SC
Externí odkaz:
https://doaj.org/article/82ff2da9444a43a6a007bc143d2a310b
Autor:
Karolina Palucka, Sangkon Oh, Jacques Banchereau, Virginia Pascual, Yong-Jun Liu, Stephen Nishimura, Joyce O'Shaughnessy, G. Jackson Snipes, Alexander Pedroza-Gonzalez, Esperanza Anguiano, Jan Martinek, Chun I. Yu, Florentina Marches, Romain Banchereau, Kangling Xu, Te-Chia Wu
PDF file - PDF file, Supplementary Table 3. PALO_0.01_TTest_0.05_1.5xUp in PMB + Curdlan vs CTL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ed16a800f38b682097bf0dc483dd7a
https://doi.org/10.1158/2326-6066.22537556.v1
https://doi.org/10.1158/2326-6066.22537556.v1
Autor:
Karolina Palucka, Sangkon Oh, Jacques Banchereau, Virginia Pascual, Yong-Jun Liu, Stephen Nishimura, Joyce O'Shaughnessy, G. Jackson Snipes, Alexander Pedroza-Gonzalez, Esperanza Anguiano, Jan Martinek, Chun I. Yu, Florentina Marches, Romain Banchereau, Kangling Xu, Te-Chia Wu
PDF file - 35K, Breast cancer cell lines were characterized which were based on original tissue, histopathological diagnosis and the receptor status (progesterone receptor, estrogen receptor, Her-2 and Insulin-like Growth Factor I Receptor).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4912fa3090ffc3f4615e4147e10d7d
https://doi.org/10.1158/2326-6066.22537559.v1
https://doi.org/10.1158/2326-6066.22537559.v1
Autor:
Karolina Palucka, Sangkon Oh, Jacques Banchereau, Virginia Pascual, Yong-Jun Liu, Stephen Nishimura, Joyce O'Shaughnessy, G. Jackson Snipes, Alexander Pedroza-Gonzalez, Esperanza Anguiano, Jan Martinek, Chun I. Yu, Florentina Marches, Romain Banchereau, Kangling Xu, Te-Chia Wu
PDF file - 37K, Supplementary Table 1. Primary breast tumor samples were received from Baylor University Medical Center.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca98ba04cc5b0e4588aba04849e8088
https://doi.org/10.1158/2326-6066.22537565
https://doi.org/10.1158/2326-6066.22537565
Autor:
Karolina Palucka, Sangkon Oh, Jacques Banchereau, Virginia Pascual, Yong-Jun Liu, Stephen Nishimura, Joyce O'Shaughnessy, G. Jackson Snipes, Alexander Pedroza-Gonzalez, Esperanza Anguiano, Jan Martinek, Chun I. Yu, Florentina Marches, Romain Banchereau, Kangling Xu, Te-Chia Wu
Our studies showed that tumor-infiltrating dendritic cells (DC) in breast cancer drive inflammatory Th2 (iTh2) cells and protumor inflammation. Here, we show that intratumoral delivery of the β-glucan curdlan, a ligand of dectin-1, blocks the genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::003f4afea70efebbc8c69ffdd599fc5a
https://doi.org/10.1158/2326-6066.c.6548477.v1
https://doi.org/10.1158/2326-6066.c.6548477.v1
Publikováno v:
Trends in Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab21de4c2d28ee895f3cccd920080273
https://doi.org/10.1016/j.trecan.2023.03.009
https://doi.org/10.1016/j.trecan.2023.03.009
Autor:
Karolina Palucka, Chun I. Yu, Gabby Aucello, Elaheh Ahmadzadeh, Jan Martinek, Florentina Marches
Publikováno v:
Cancer Research. 80:P1-04
The interaction between various components in the tumor environment plays a pivotal role in tumor development, migration and metastasis. While the 2-dimensional (2D) in vitro culture methods fail to assimilate the complexity of tumor microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d78586a6fcdad795824bb03368415be7
https://doi.org/10.1158/1538-7445.sabcs19-p1-04-02
https://doi.org/10.1158/1538-7445.sabcs19-p1-04-02
Autor:
Chun I. Yu, Francesca Menghi, Florentina Marches, Karolina Palucka, Te-Chia Wu, Vanessa Oliveira, Jacques Banchereau, Edison T. Liu, Kyung In Kim
Publikováno v:
Cancer Research. 80:P1-03
Triple-negative breast cancer (TNBC) is a particularly aggressive form of breast cancer with high risk of recurrence and approximately 22% rate of five-year survival when the disease becomes metastatic. Thus, understanding of mechanisms supporting me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7acbcb42420b0d897a2a494a2cd5af
https://doi.org/10.1158/1538-7445.sabcs19-p1-03-05
https://doi.org/10.1158/1538-7445.sabcs19-p1-03-05
Autor:
Pierre Authie, Chun I. Yu, Kyung In Kim, Te-Chia Wu, Karolina Palucka, Vanessa Oliveira, Richard S. Maser, Jeffrey H. Chuang, Jacques Banchereau, Victor Wang, Jan Martinek, Florentina Marches, Elaheh Ahmadzadeh, Paul Robson, Patrick Metang, Joshy George
Publikováno v:
The Journal of Experimental Medicine
Colonization of visceral organs with melanoma in humanized NSG-SGM3 mice is dependent upon human CD33+CD11b+CD117+ progenitor cells. A gene signature of KIT/CD117–expressing CD33+ subset correlates with decreased overall survival in TCGA melanoma s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5aaf2d762d8d09d77fb655a3f8f427
https://doi.org/10.1084/jem.20182163
https://doi.org/10.1084/jem.20182163