Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chun Fang Shen"'
Publikováno v:
Vaccines, Vol 12, Iss 5, p 524 (2024)
Adenoviruses are efficient and safe vectors for delivering target antigens and adenovirus-based vaccines have been used against a wide variety of pathogens, including tuberculosis and COVID-19. Cost-effective and scalable biomanufacturing processes a
Externí odkaz:
https://doaj.org/article/73dc1a4654dc433ab6363bfeb86b5dfc
Autor:
Chun Fang, Shen, Sonia, Tremblay, Catherine, Sabourin-Poirier, Elodie, Burney, Sophie, Broussau, Aziza, Manceur, Anja, Rodenbrock, Robert, Voyer, Martin, Loignon, Sven, Ansorge, Rénald, Gilbert
Publikováno v:
Bioprocess and Biosystems Engineering. 45:1267-1280
The growing interest in the use of lentiviral vectors (LVs) for various applications has created a strong demand for large quantities of vectors. To meet the increased demand, we developed a high cell density culture process for production of LV usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a15eeff6d25f501b0ccebb0724e4bc
https://doi.org/10.1007/s00449-022-02737-5
https://doi.org/10.1007/s00449-022-02737-5
Autor:
Rénald Gilbert, Claire Guilbault, Amine Kamen, Sven Ansorge, S. Mehdy Elahi, Xiuling Li, Chun Fang Shen
Publikováno v:
Vaccine. 37:6996-7002
Vero cells are considered as the most widely accepted continuous cell line by the regulatory authorities (such as WHO) for the manufacture of viral vaccines for human use. The growth of Vero cells is anchorage-dependent. Scale-up and manufacturing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9b28553f3780708df61fa019dc334b
https://doi.org/10.1016/j.vaccine.2019.07.003
https://doi.org/10.1016/j.vaccine.2019.07.003
The Vero cell line is the most used continuous cell line in viral vaccine manufacturing. This adherent cell culture platform requires the use of surfaces to support cell growth, typically roller bottles or microcarriers. We have recently compared the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9140e4455297eacf054ec8970828d074
https://doi.org/10.22541/au.161044033.35250019/v1
https://doi.org/10.22541/au.161044033.35250019/v1
Publikováno v:
Journal of virological methods. 275
Viral vectors derived from vesicular stomatitis virus (VSV) are important vectors for the development of vaccines and for the treatment of cancer. The efficiency of therapy based on VSV is dependent on the dose of virus used. Therefore it is essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391362f34759104737373b71fdb2c7f7
https://pubmed.ncbi.nlm.nih.gov/31678047
https://pubmed.ncbi.nlm.nih.gov/31678047
During the last decade, oncolytic viruses such as vesicular stomatitis virus (VSV) have gained tremendous popularity as efficient vaccines for infectious diseases as well as for the treatment of cancer. Our laboratory has developed two stable cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a5e2231714422939cd7c5eada6d830
https://doi.org/10.1016/j.jbiotec.2018.11.023
https://doi.org/10.1016/j.jbiotec.2018.11.023
Autor:
Stéphane Lanthier, Danielle Jacob, Zhu Tao, Shao Zhongqi, Yu Xuefeng, Amine Kamen, Mehul Patel, Alice Bernier, Chun Fang Shen
Publikováno v:
Vaccine. 34(29)
Tuberculosis (TB) is the second leading cause of death by infectious disease worldwide. The only available TB vaccine is the Bacille Calmette–Guerin (BCG). However, parenterally administered Mycobacterium bovis BCG vaccine confers only limited immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61687e8bd0848575c7c087f4c52cdccb
https://pubmed.ncbi.nlm.nih.gov/27154390
https://pubmed.ncbi.nlm.nih.gov/27154390
Autor:
Qun Yan, Chen Xu, Jie Hong, Meng Dai, W. Gu, Man-yin Xu, Qiaorui Liu, Guang Ning, Zhen-ni Chi, Chun-fang Shen, Xiaoying Li, Yu Zhang, Yuxia Su, Wei Qing Wang, Yi Zhang
Publikováno v:
Diabetes & Metabolism. 36:470-475
Retinol-binding protein 4 (RBP4) is thought to be associated with insulin resistance in humans, while pregnancy is normally characterized by progressive insulin resistance. Gestational diabetes (GDM) occurs when pancreatic beta-cell function is unabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50acb6951b84a08aad082cb5b69a97a8
https://doi.org/10.1016/j.diabet.2010.06.006
https://doi.org/10.1016/j.diabet.2010.06.006
Autor:
Weiqiong Gu, Guang Ning, Huiying Jia, Bin Cui, Lei Ye, Yan Ge, Yuwen Zhang, Jie Hong, Xiaoying Li, Weiqing Wang, Huijie Zhang, Chun-fang Shen, Yifei Zhang
Publikováno v:
Endocrine. 36:37-44
Prader-Willi syndrome (PWS) is a complex, genetic, multisystem disorder. Its major clinical features include neonatal hypotonia and failure to thrive, mental retardation, hypogonadism, short hands and feet, hyperphagia-caused obesity, and characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c50702c9826376c39bcc02a6c88493
https://doi.org/10.1007/s12020-009-9203-1
https://doi.org/10.1007/s12020-009-9203-1
Autor:
Yifei Zhang, Jie Hong, Chun-fang Shen, Weiqiong Gu, Weiqing Wang, Guang Ning, Min Xu, Xiaoying Li, Yi-Sheng Yang
Publikováno v:
Endocrine. 31:93-99
Type 2 diabetes mellitus (T2DM) is a heterogeneous disorder characterized by defects in insulin secretion and action and obesity plays an important role in the deterioration of glucose metabolism. In the present study we evaluated the degree of insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb2df4f8fcc1ad241eaa2daad2aa8fd
https://doi.org/10.1007/s12020-007-0002-2
https://doi.org/10.1007/s12020-007-0002-2