Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Chun Chia Cheng"'
Autor:
Wei-Chen Yen, Kai-Ping Chang, Cheng-Yi Chen, Yenlin Huang, Ting-Wen Chen, Hsing-Wen Cheng, Jui-Shan Yi, Chun-Chia Cheng, Chih-Ching Wu, Chun-I Wang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Oral squamous cell carcinoma (OSCC) is the predominant histological type of the head and neck squamous cell carcinoma (HNSCC). By comparing the differentially expressed genes (DEGs) in OSCC-TCGA patients with copy number variations (CNVs) th
Externí odkaz:
https://doaj.org/article/e705d9304dc0453694da67258ba7bbb8
Autor:
Yi-Fang Chang, Ken-Hong Lim, Ya-Wen Chiang, Zong-Lin Sie, Jungshan Chang, Ai-Sheng Ho, Chun-Chia Cheng
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background HER3 mediates drug resistance against epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs), resulting in tumor relapse in lung cancers. Previously, we demonstrated that EGFR induces HER3 overexpression, which
Externí odkaz:
https://doaj.org/article/cb61132664c64b758ae2440f5c1e07b1
Autor:
Szu‐Yuan Wu, Wan‐Yu Yang, Chun‐Chia Cheng, Kuan‐Hao Lin, Bonifasius Putera Sampurna, Suat‐Ming Chan, Chiou‐Hwa Yuh
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 8, Pp n/a-n/a (2020)
Abstract Background Hepatocellular carcinoma ranks fourth in cancer‐related mortality currently lacks effective therapeutics. Fucoidan is sulfated polysaccharide that is mainly found in brown seaweeds. In this study, we investigated the effects and
Externí odkaz:
https://doaj.org/article/73c5f727d3a8456cace8dc4a06868098
Autor:
Tzu-Chun Kan, Mei-Hsiang Lin, Chun-Chia Cheng, Jeng-Wei Lu, Ming-Thau Sheu, Yuan-Soon Ho, Sri Rahayu, Jungshan Chang
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 839 (2022)
Cisplatin is one of the most common therapeutics used in treatments of several types of cancers. To enhance cisplatin lipophilicity and reduce resistance and side effects, a polyfluorinated bipyridine-modified cisplatin analogue, dichloro[4,4’-bis(
Externí odkaz:
https://doaj.org/article/544131621a934047b7c9de05ddc9bc17
Autor:
Giimel Ajnai, Chun-Chia Cheng, Tzu-Chun Kan, Jeng-Wei Lu, Sri Rahayu, Amy Chiu, Jungshan Chang
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 847 (2022)
Tumor hypoxia is a hallmark of solid tumors and emerged as the therapeutic target for cancer treatments, such as a prodrug Tirapazamine (TPZ) activated in hypoxia. To increase tumor accumulation, gold nanoparticles (GNPs) were selected to conjugate w
Externí odkaz:
https://doaj.org/article/aad744552299478a892f4cfecdeccfa4
Autor:
Chih-Liang Wang, Ai-Sheng Ho, Chun-Chao Chang, Zong-Lin Sie, Cheng-Liang Peng, Jungshan Chang, Chun-Chia Cheng
Publikováno v:
Cancer Immunology, Immunotherapy. 72:1865-1880
Radiotherapy (RT) not only damages tumors but also induces interferon (IFN) expression in tumors. IFNs mediate PD-L1 to exhaust CD8+ T cells, but which also directly impact tumor cells and potentially activate anti-tumor immune surveillance. Little i
Autor:
Chun-Chia Cheng, Po-Nien Liao, Ai-Sheng Ho, Ken-Hong Lim, Jungshan Chang, Ying-Wen Su, Caleb Gon-Shen Chen, Ya-Wen Chiang, Bi-Ling Yang, Huan-Chau Lin, Yu-Cheng Chang, Chun-Chao Chang, Yi-Fang Chang
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-12 (2018)
Abstract Background Cancer stem cells are capable of undergoing cell division after surviving cancer therapies, leading to tumor progression and recurrence. Inhibitory agents against cancer stem cells may be therapeutically used for efficiently eradi
Externí odkaz:
https://doaj.org/article/6fa8fbb263aa47dc8b21de866be2cfc8
Autor:
Chun-Chia Cheng, Yi-Fang Chang, Ai-Sheng Ho, Zong-Lin Sie, Jung-Shan Chang, Cheng-Liang Peng, Chun-Chao Chang
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1349 (2021)
Irradiation-broken DNA fragments increase type I interferon and chemokines secretion in tumor cells. Since radiotherapy may augment tumor immunotherapy, we hypothesize that the chemokines increased by irradiation could recruit CD8+ T cells to suppres
Externí odkaz:
https://doaj.org/article/ce04b150a5124871b008367f2df050a0
Autor:
Chun-I. Wang, Yi-Fang Chang, Zong-Lin Sie, Ai-Sheng Ho, Jung-Shan Chang, Cheng-Liang Peng, Chun-Chia Cheng
Publikováno v:
Cells, Vol 10, Iss 10, p 2515 (2021)
Tumor cells express immune checkpoints to exhaust CD8+ T cells. Irradiation damages tumor cells and augments tumor immunotherapy in clinical applications. However, the radiotherapy-mediated molecular mechanism affecting CD8+ T cell activity remains e
Externí odkaz:
https://doaj.org/article/4b52418cbd594aae840c6aa3d1c19614
Autor:
Wei-Chen Yen, Kai-Ping Chang, Cheng-Yi Chen, Yenlin Huang, Ting-Wen Chen, Hsing-Wen Cheng, Jui-Shan Yi, Chun-Chia Cheng, Chih-Ching Wu, Chun-I Wang
Oral squamous cell carcinoma (OSCC) is the predominant histological type of the head and neck squamous cell carcinoma (HNSCC). By comparing the differentially expressed genes (DEGs) in OSCC-TCGA patients with copy number variations (CNVs) that we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea26f0b765ae379eeb3cdb8748206d0
https://doi.org/10.21203/rs.3.rs-2275193/v1
https://doi.org/10.21203/rs.3.rs-2275193/v1