Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Chun C. Chao"'
Publikováno v:
The Journal of Infectious Diseases. 182:200-205
Infection by human granulocytic ehrlichiosis (HGE) is characterized clinically by cytopenias out of proportion to the number of cells seen to be infected directly. To study the pathogenic role of inflammatory mediators in HGE infection, cytokine prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5999135fa1981a7f24ea3ecd8d4bf1b0
https://doi.org/10.1086/315641
https://doi.org/10.1086/315641
Autor:
Melvyn P. Heyes, James R. Lokensgard, Phillip K. Peterson, Shuxian Hu, Genya Gekker, Chun C. Chao
Publikováno v:
Neuropharmacology. 39:150-160
The pathogenesis of human immunodeficiency virus type 1 (HIV-1) encephalopathy has been associated with multiple factors including the neurotoxin quinolinate (an endogenous N-methyl-D-aspartate [NMDA] receptor ligand) and viral proteins. The kappa op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a13b6354b27a0f6dfb4308f8e879d4c
https://doi.org/10.1016/s0028-3908(99)00063-5
https://doi.org/10.1016/s0028-3908(99)00063-5
Publikováno v:
Glia. 32:155-164
Polymorphonuclear neutrophils (PMNs) are known to mediate brain inflammation following hypoxia/reoxygenation (H/R), but the precise mechanisms leading to PMN recruitment are undefined. The alpha-chemokine macrophage inflammatory protein-2 (MIP-2) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2087441e4787ea2bdedf1795932cbb19
https://doi.org/10.1002/1098-1136(200011)32:2<155::aid-glia50>3.0.co
https://doi.org/10.1002/1098-1136(200011)32:2<155::aid-glia50>3.0.co
Autor:
James R. Lokensgard, Phillip K. Peterson, Genya Gekker, Philip S. Portoghese, Chun C. Chao, Shuxian Hu
Publikováno v:
Neuropharmacology. 38:273-278
Endogneous delta and kappa opioid peptides possess a variety of immunomodulatory properties, and kappa-opioid receptor ligands recently were shown to suppress the expression of human immunodeficiency virus type 1 (HIV-1) in microglial cells, the resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0ce243f35d24e7e7c6860f7010172f
https://doi.org/10.1016/s0028-3908(98)00167-1
https://doi.org/10.1016/s0028-3908(98)00167-1
Publikováno v:
NeuroReport. 10:177-181
Activation of the immune system has been associated with the development of fatigue of unknown cause. We were interested in brain energy stores (e.g., phosphocreatine (PCr) and creatine kinase) after immune activation to investigate whether this syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2313c1306999c69aace540419ba98481
https://doi.org/10.1097/00001756-199901180-00034
https://doi.org/10.1097/00001756-199901180-00034
Publikováno v:
Molecular Neurobiology. 18:23-33
Although the precise mechanisms whereby HIV-1 infection induces neurodegeneration have yet to be determined, a great deal of evidence has incriminated glial cells and the production of proinflammatory mediators in this pathologic process. For this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210c807faa7e84ad7b10df90fe4f2de9
https://doi.org/10.1007/bf02741458
https://doi.org/10.1007/bf02741458
Publikováno v:
Biochemical Pharmacology. 56:397-404
Opioids have been postulated to play an immunomodulatory role in the pathogenesis of HIV-1. Synthetic kappa-opioid receptor (KOR) ligands have been found to inhibit HIV-1 expression in acutely infected microglial cell cultures. We recently found that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804fcce7ae5e97ac5775340463d61ec8
https://doi.org/10.1016/s0006-2952(98)00161-0
https://doi.org/10.1016/s0006-2952(98)00161-0
Publikováno v:
Biochemical Pharmacology. 56:289-292
Delta-opioid receptor (DOR) transcripts and binding sites are expressed by lymphocytes and lymphoid cell lines from several species. Direct modulation of lymphocyte function through DORs affects T cell proliferation, interleukin-2 production, chemota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd73003df6fc5ecec5695834b030462f
https://doi.org/10.1016/s0006-2952(98)00155-5
https://doi.org/10.1016/s0006-2952(98)00155-5
Autor:
Kendra L. Burgher, Chun C Chao, Sheng Zu Zhu, Garth E. Ringheim, Ann Marie Szczepanik, Wayne Petko
Publikováno v:
Molecular Brain Research. 55:35-44
We investigated a potential role for the soluble interleukin-6 receptor (sIL-6R) in modulating interleukin-6 (IL-6) function in the central nervous system by assessing IL-6 and sIL-6R effects on beta-amyloid precursor protein (beta-APP) transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2c17404fe8a655610bd9a67fe41559
https://doi.org/10.1016/s0169-328x(97)00356-2
https://doi.org/10.1016/s0169-328x(97)00356-2
Autor:
Chun C. Chao, William F. Keane, Kulwant S. Modi, Genya Gekker, Bertram L. Kasiske, Michael P. O'Donnell
Publikováno v:
Kidney International. 53:593-597
Renal cell cytokine production stimulates HIV-1 expression in chronically HIV-1-infected monocytes. Renal infiltration of human immunodeficiency virus type 1 (HIV-1)-infected monocytes might play an important role in the development of HIV-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c37130bdd4be909fff89185be71574
https://doi.org/10.1046/j.1523-1755.1998.00789.x
https://doi.org/10.1046/j.1523-1755.1998.00789.x