Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Chun A. Changou"'
Autor:
Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, Shian-Ying Sung, Alice L. Yu, Yun Yen, Tai-Tong Wong, Che-Chang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Atypical teratoid rhabdoid tumors (ATRT) is a rare but aggressive malignancy in the central nervous system, predominantly occurring in early childhood. Despite aggressive treatment, the prognosis of ATRT patients remains poor. RRM
Externí odkaz:
https://doaj.org/article/e574275cddf349a6bfdc6e8be6ff72fb
Autor:
Yi-Ping Chen, Chih-Ming Chou, Tsu-Yuan Chang, Hao Ting, Julien Dembélé, You-Tai Chu, Tsang-Pai Liu, Chun A. Changou, Chien-Wei Liu, Chien-Tsu Chen
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The blood–brain barrier (BBB) is a highly selective cellular barrier that tightly controls the microenvironment of the central nervous system to restrict the passage of substances, which is a primary challenge in delivering therapeutic drugs to tre
Externí odkaz:
https://doaj.org/article/05a951de4a35476b9f148b9dfbb42a33
Autor:
Kuan-Wei Su, Hung-Yun Lin, Hsien-Chung Chiu, Shin-Yu Shen, Chun A. ChangOu, Dana R. Crawford, Yu-Chen S. H. Yang, Ya-Jung Shih, Zi-Lin Li, Haw-Ming Huang, Jaqueline Whang-Peng, Yih Ho, Kuan Wang
Publikováno v:
Cells, Vol 11, Iss 19, p 3050 (2022)
Oral cancer is a fatal disease, and its incidence in Taiwan is increasing. Thyroid hormone as L-thyroxine (T4) stimulates cancer cell proliferation via a receptor on integrin αvβ3 of plasma membranes. It also induces the expression of programmed de
Externí odkaz:
https://doaj.org/article/c64f343599974917a6dd74258222602d
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Abstract Introduction Efficacy and safety are critical concerns when designing drug carriers. Nanoparticles are a particular type of carrier that has gained recent attention in cancer therapeutics. Methods In this study, we assess the safety profile
Externí odkaz:
https://doaj.org/article/e3b0ecfe47aa4b3880c1378177bb026b
Autor:
Wen-Jui Lee, Shih-Hsin Tu, Tzu-Chun Cheng, Juo-Han Lin, Ming-Thau Sheu, Ching-Chuan Kuo, Chun A. Changou, Chih-Hsiung Wu, Hui-Wen Chang, Hang-Lung Chang, Li-Ching Chen, Yuan-Soon Ho
Publikováno v:
Molecules, Vol 26, Iss 21, p 6548 (2021)
The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein and its enzymatic product hyaluronic acid (HA) encompassed in the subcutaneous extracellul
Externí odkaz:
https://doaj.org/article/75da9fb660f848f9a5d1943f57c0c831
Autor:
Yu-Tang Chin, Le-Ming Wang, Meng-Ti Hsieh, Ya-Jung Shih, André Wendindondé Nana, Chun A. Changou, Yu-Chen S. H. Yang, Hsien-Chung Chiu, Earl Fu, Paul J. Davis, Heng-Yuan Tang, Hung-Yun Lin
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-13 (2017)
Abstract Background Obesity and its comorbidities constitute a serious health burden worldwide. Leptin plays an important role in diet control; however, it has a stimulatory potential on cancer cell proliferation. The OB3 peptide, a synthetic peptide
Externí odkaz:
https://doaj.org/article/9f0bb2f0336f46d7ba7618d42b58e144
Autor:
Jing-Wen Shih, Wei-Fan Chiang, Alexander T. H. Wu, Ming-Heng Wu, Ling-Yu Wang, Yen-Ling Yu, Yu-Wen Hung, Wen-Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung, Chun A. Changou, Yun Yen, Hsing-Jien Kung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show
Externí odkaz:
https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a
Autor:
Tung-Yung Huang, Tung-Cheng Chang, Yu-Tang Chin, Yi-Shin Pan, Wong-Jin Chang, Feng-Cheng Liu, Ema Dwi Hastuti, Shih-Jiuan Chiu, Shwu-Huey Wang, Chun A. Changou, Zi-Lin Li, Yi-Ru Chen, Hung-Ru Chu, Ya-Jung Shih, R. Holland Cheng, Alexander Wu, Hung-Yun Lin, Kuan Wang, Jacqueline Whang-Peng, Shaker A Mousa, Paul J. Davis
Publikováno v:
Cells, Vol 9, Iss 8, p 1830 (2020)
The property of drug-resistance may attenuate clinical therapy in cancer cells, such as chemoresistance to gefitinib in colon cancer cells. In previous studies, overexpression of PD-L1 causes proliferation and metastasis in cancer cells; therefore, t
Externí odkaz:
https://doaj.org/article/a2d87109f6454f45a616688aaa73d59b
Autor:
Alagie Jassey, Ching-Hsuan Liu, Chun A. Changou, Christopher D. Richardson, Hsue-Yin Hsu, Liang-Tzung Lin
Publikováno v:
Cells, Vol 8, Iss 4, p 290 (2019)
Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. Although HCV infection has been shown to induce mitophagy, the precise underlying mechanism and the effector protein responsible remain unclear. Her
Externí odkaz:
https://doaj.org/article/851074210315489493f32f6228a8d34e
Autor:
Yu-Wen Wu, Deng-Yao Lee, Yeh-Lin Lu, Liling Delila, Ouada Nebie, Lassina Barro, Chun Austin Changou, Long-Sheng Lu, Hadi Goubran, Burnouf, Thierry
Publikováno v:
Platelets; Dec2023, Vol. 34 Issue 1, p1-12, 12p