Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Chun–Woong Park"'
Autor:
Hye-Ri Han, Ji Hoon Choi, Je Hwa Yoo, Jin-Hyuk Jeong, Sang-Beom Na, Ji-Hyun Kang, Dong-Wook Kim, Chun-Woong Park
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1374 (2024)
Background: This study aimed to optimize the coating process of Omega-3 fatty acid (OM3-FA) mini soft capsules containing the active pharmaceutical ingredients (APIs) pitavastatin and ezetimibe using near-infrared (NIR) spectroscopy for in-process mo
Externí odkaz:
https://doaj.org/article/69c6138884b843daa231b1f3784331df
Autor:
Jin-Hyuk Jeong, Ji-Su Kim, Yu-Rim Choi, Dae Hwan Shin, Ji-Hyun Kang, Dong-Wook Kim, Yun-Sang Park, Chun-Woong Park
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 784 (2024)
Dry-powder inhalers (DPIs) are valued for their stability but formulating them is challenging due to powder aggregation and limited flowability, which affects drug delivery and uniformity. In this study, the incorporation of L-leucine (LEU) into hot-
Externí odkaz:
https://doaj.org/article/0cd4841684a142b1aa4aa825797280ec
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 783 (2024)
The aim of this study was to fabricate mini-tablets of polyhedrons containing theophylline using a fused deposition modeling (FDM) 3D printer, and to evaluate the correlation between release kinetics models and their geometric shapes. The filaments c
Externí odkaz:
https://doaj.org/article/f176d240bcac405db663bdbe08ff5557
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 3384-3396 (2022)
Pirfenidone (PRF) is the first FDA-approved API in the treatment of idiopathic pulmonary fibrosis (IPF). However, PRF induces serious side effects, such as photophobia and gastrointestinal disorder. PRF inhalation can be expected with a lower effecti
Externí odkaz:
https://doaj.org/article/6cdeb3866254430a9d2b1afc7bb22607
Autor:
Chang-Soo Han, Ji-Hyun Kang, Eun hye Park, Hyo-Jung Lee, So-Jeong Jeong, Dong-Wook Kim, Chun-Woong Park
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 3, Pp 100815- (2023)
Corrugated surface microparticles comprising levofloxacin (LEV), chitosan and organic acid were prepared using the 3-combo spray drying method. The amount and the boiling point of the organic acid affected the degree of roughness. In this study, we t
Externí odkaz:
https://doaj.org/article/8e078a35ebaf4bbc97d84729ab1963b5
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1696 (2023)
The conventional dosage form of Ethyol® (amifostine), a sterile lyophilized powder, involves reconstituting it with 9.7 mL of sterile 0.9% sodium chloride in accordance with the United States Pharmacopeia specifications for intravenous infusion. The
Externí odkaz:
https://doaj.org/article/0e6ef6660ec84cddb0aa71dd7b805a65
Autor:
Chae Eun Jin, Moon Sup Yoon, Min Jeong Jo, Seo Yeon Kim, Jae Min Lee, Su Jeong Kang, Chun-Woong Park, Jin-Seok Kim, Dae Hwan Shin
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1206 (2023)
Ovarian cancer has a high mortality rate due to difficult detection at an early stage. It is necessary to develop a novel anticancer treatment that demonstrates improved efficacy while reducing toxicity. Here, using the freeze-drying method, micelles
Externí odkaz:
https://doaj.org/article/7bd7f8ee609947a2b2efe76e5c27c39a
Autor:
Min Jeong Jo, Hee Ji Shin, Moon Sup Yoon, Seo Yeon Kim, Chae Eun Jin, Chun-Woong Park, Jin-Seok Kim, Dae Hwan Shin
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 154 (2023)
Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms, allowing multiple pathways to be targeted simultaneously, effectively treating various cancers. However, these drugs have a low hydrosolubility, limiting clinical appl
Externí odkaz:
https://doaj.org/article/d8b3728003fb416eb231da3e87e21d8b
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1409 (2022)
This study aimed to prepare mucus-penetrating inhalable microparticles for dry powder inhalers and to evaluate their applicability in an asthma-induced rat model. Microparticles were prepared from water solutions containing tiotropium bromide, L-leuc
Externí odkaz:
https://doaj.org/article/aa413624af824dd6935e7308a0361b79
Autor:
Taek Kwan Kwon, Ji-Hyun Kang, Sang-Beom Na, Jae Ho Kim, Yong-Il Kim, Dong-Wook Kim, Chun-Woong Park
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1411 (2022)
Esomeprazole magnesium (EMP) is a proton pump inhibitor (PPI) that reduces acid secretion. EMP has a short plasma half-life (approximately 1.3 h); hence, nocturnal acid breakthrough (NAB) frequently occurs, disturbing the patient’s nighttime comfor
Externí odkaz:
https://doaj.org/article/f1faf2e6dd95467e858c5ba98aa9d0a0