Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Chun‐Yuan Chen"'
Young osteocyte-derived extracellular vesicles facilitate osteogenesis by transferring tropomyosin-1
Autor:
Zhen-Xing Wang, Xiao Lin, Jia Cao, Yi-Wei Liu, Zhong-Wei Luo, Shan-Shan Rao, Qiang Wang, Yi-Yi Wang, Chun-Yuan Chen, Guo-Qiang Zhu, Fu-Xing-Zi Li, Yi-Juan Tan, Yin Hu, Hao Yin, You-You Li, Ze-Hui He, Zheng-Zhao Liu, Ling-Qing Yuan, Yong Zhou, Zheng-Guang Wang, Hui Xie
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Bone marrow mesenchymal stem cells (BMSCs) can undergo inadequate osteogenesis or excessive adipogenesis as they age due to changes in the bone microenvironment, ultimately resulting in decreased bone density and elevated risk of
Externí odkaz:
https://doaj.org/article/da5fc480e6374e0f89eb84ea01578db5
Autor:
Jia Cao, Ling Jin, Zi-Qi Yan, Xiao-Kai Wang, You-You Li, Zun Wang, Yi-Wei Liu, Hong-Ming Li, Zhe Guan, Ze-Hui He, Jiang-Shan Gong, Jiang-Hua Liu, Hao Yin, Yi-Juan Tan, Chun-Gu Hong, Shi-Kai Feng, Yan Zhang, Yi-Yi Wang, Lu-Yue Qi, Chun-Yuan Chen, Zheng-Zhao Liu, Zhen-Xing Wang, Hui Xie
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Endothelial cells (ECs) and bone marrow stromal cells (BMSCs) play crucial roles in supporting hematopoiesis and hematopoietic regeneration. However, whether ECs are a source of BMSCs remains unclear. Here, we evaluate the contribution of en
Externí odkaz:
https://doaj.org/article/4e0e17bbb4dc4421b93305f72ce50a9b
Autor:
Zhe Ruan, Hao Yin, Teng-Fei Wan, Zhi-Rou Lin, Shu-Shan Zhao, Hai-Tao Long, Cheng Long, Zhao-Hui Li, Yu-Qi Liu, Hao Luo, Liang Cheng, Can Chen, Min Zeng, Zhang-Yuan Lin, Rui-Bo Zhao, Chun-Yuan Chen, Zhen-Xing Wang, Zheng-Zhao Liu, Jia Cao, Yi-Yi Wang, Ling Jin, Yi-Wei Liu, Guo-Qiang Zhu, Jing-Tao Zou, Jiang-Shan Gong, Yi Luo, Yin Hu, Yong Zhu, Hui Xie
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Due to increasing morbidity worldwide, fractures are becoming an emerging public health concern. This study aimed to investigate the effect of metformin on the healing of osteoporotic as well as normal fractures. Type H vessels have recently
Externí odkaz:
https://doaj.org/article/ec1134f66c5543bf81f160d8dee444a9
Autor:
Zhen-Xing Wang, Zhong-Wei Luo, Fu-Xing-Zi Li, Jia Cao, Shan-Shan Rao, Yi-Wei Liu, Yi-Yi Wang, Guo-Qiang Zhu, Jiang-Shan Gong, Jing-Tao Zou, Qiang Wang, Yi-Juan Tan, Yan Zhang, Yin Hu, You-You Li, Hao Yin, Xiao-Kai Wang, Ze-Hui He, Lu Ren, Zheng-Zhao Liu, Xiong-Ke Hu, Ling-Qing Yuan, Ran Xu, Chun-Yuan Chen, Hui Xie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
This study uncovers the role of extracellular vesicles from bone matrix as a messenger in the development of osteoporosis and vascular calcification (calcification paradox) during skeletal aging and menopause by transferring miR-483-5p and miR-2861.
Externí odkaz:
https://doaj.org/article/ab6085afb96c4c6ca3fad64ef9bffdb0
Autor:
Hong-Mou Shih, Szu-Yu Pan, Chih-Jen Wu, Yu-Hsiang Chou, Chun-Yuan Chen, Fan-Chi Chang, Yi-Ting Chen, Wen-Chih Chiang, Hsing-Chen Tsai, Yung-Ming Chen, Shuei-Liong Lin
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Renal erythropoietin (EPO)-producing (REP) cells produce EPO through hypoxia-inducible factor (HIF) 2α-activated gene transcription. Insufficient EPO production leads to anemia in patients with chronic kidney disease. Although re
Externí odkaz:
https://doaj.org/article/4cecab6670294871beec1077d0bd73b3
Autor:
Shuliang Chen, Melissa A. Roberts, Chun-Yuan Chen, Sebastian Markmiller, Hong-Guang Wei, Gene W. Yeo, James G. Granneman, James A. Olzmann, Susan Ferro-Novick
Publikováno v:
Contact, Vol 5 (2022)
Lipid transfer proteins mediate the exchange of lipids between closely apposed membranes at organelle contact sites and play key roles in lipid metabolism, membrane homeostasis, and cellular signaling. A recently discovered novel family of lipid tran
Externí odkaz:
https://doaj.org/article/1e1a9db2ba5f434ba1ddfd7413e4ae42
Autor:
James Yeongjun Park, Tzu-Chun Hsu, Jiun-Ruey Hu, Chun-Yuan Chen, Wan-Ting Hsu, Matthew Lee, Joshua Ho, Chien-Chang Lee
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 4, p e29982 (2022)
BackgroundAlthough machine learning (ML) algorithms have been applied to point-of-care sepsis prognostication, ML has not been used to predict sepsis mortality in an administrative database. Therefore, we examined the performance of common ML algorit
Externí odkaz:
https://doaj.org/article/e26590b2b9ea4a1ea518c1f7f616c0c0
Publikováno v:
Education Sciences, Vol 13, Iss 2, p 113 (2023)
This study explored two issues: (1) could the number of design awards represent the design level of a country? (2) If the design award is not suitable as criterion, is there a more appropriate one(s)? Beginning with the phenomenon that use the number
Externí odkaz:
https://doaj.org/article/b192564d6e27474fb6b5a587fdfcbedd
Autor:
Yan Zhang, Chun‐Yuan Chen, Yi‐Wei Liu, Shan‐Shan Rao, Yi‐Juan Tan, Yu‐Xuan Qian, Kun Xia, Jie Huang, Xi‐Xi Liu, Chun‐Gu Hong, Hao Yin, Jia Cao, Shi‐Kai Feng, Ze‐Hui He, You‐You Li, Zhong‐Wei Luo, Ben Wu, Zi‐Qi Yan, Tuan‐Hui Chen, Meng‐Lu Chen, Yi‐Yi Wang, Zhen‐Xing Wang, Zheng‐Zhao Liu, Ming‐Jie Luo, Xiong‐Ke Hu, Ling Jin, Teng‐Fei Wan, Tao Yue, Si‐Yuan Tang, Hui Xie
Publikováno v:
Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract A differentiation switch of bone marrow mesenchymal stem/stromal cells (BMSCs) from osteoblasts to adipocytes contributes to age‐ and menopause‐associated bone loss and marrow adiposity. Here it is found that osteocytes, the most abundan
Externí odkaz:
https://doaj.org/article/c95444b404b64534abd3b7ebb0ee29c2
Publikováno v:
Micromachines, Vol 13, Iss 9, p 1505 (2022)
This paper proposes a new 6T1C pixel circuit based on low-temperature polycrystalline oxide (LTPO) technology for portable active-matrix organic light-emitting diode (AMOLED) displays with variable refresh rates ranging from 1 to 120 Hz. The proposed
Externí odkaz:
https://doaj.org/article/0168d7f4860f4c509820ace710bfbed3