Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Chun‐Long Chen"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/7506e571b9a54ccea4b082a96ceed9aa
Autor:
Renyu Zheng, Mingfei Zhao, Jingshan S. Du, Tarunya Rao Sudarshan, Yicheng Zhou, Anant K. Paravastu, James J. De Yoreo, Andrew L. Ferguson, Chun-Long Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract A long-standing challenge in bioinspired materials is to design and synthesize synthetic materials that mimic the sophisticated structures and functions of natural biomaterials, such as helical protein assemblies that are important in biolog
Externí odkaz:
https://doaj.org/article/521fcd784d1d4b9bb5700b22d8befa07
Autor:
Fatima A. Davila-Hernandez, Biao Jin, Harley Pyles, Shuai Zhang, Zheming Wang, Timothy F. Huddy, Asim K. Bera, Alex Kang, Chun-Long Chen, James J. De Yoreo, David Baker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Biomolecules modulate inorganic crystallization to generate hierarchically structured biominerals, but the atomic structure of the organic-inorganic interfaces that regulate mineralization remain largely unknown. We hypothesized that heterog
Externí odkaz:
https://doaj.org/article/6cacd6f254a84ca6bc2400ddc3231925
Autor:
Chenyu Ma, Chunyan Li, Huijing Ma, Daqi Yu, Yufei Zhang, Dan Zhang, Tianhan Su, Jianmin Wu, Xiaoyue Wang, Li Zhang, Chun-Long Chen, Yong E. Zhang
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-29 (2022)
Abstract Background Despite having been extensively studied, it remains largely unclear why humans bear a particularly high risk of cancer. The antagonistic pleiotropy hypothesis predicts that primate-specific genes (PSGs) tend to promote tumorigenes
Externí odkaz:
https://doaj.org/article/ae7fef6f05344c81bbd4e6d8e84da1aa
Autor:
Tengyue Jian, Yicheng Zhou, Peipei Wang, Wenchao Yang, Peng Mu, Xin Zhang, Xiao Zhang, Chun-Long Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Peroxidase mimics are currently being investigated as catalysts for lignin depolymerisation. In this article, the authors investigate a class of self-assembled and highly stable peptoid/hemin nanomaterials as peroxidase mimics that are highly stable
Externí odkaz:
https://doaj.org/article/e024b5609e6f4c23b5482ca6b3ce4487
Autor:
Stefano Gnan, Joseph M. Josephides, Xia Wu, Manuela Spagnuolo, Dalila Saulebekova, Mylène Bohec, Marie Dumont, Laura G. Baudrin, Daniele Fachinetti, Sylvain Baulande, Chun-Long Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
A scalable approach to explore DNA replication in single cells reveals that although aneuploidy does not have a major impact on the pattern of replication, different cell types and sub-populations display distinguished replication paths.
Externí odkaz:
https://doaj.org/article/fd1aed25b9a042d2a333d9c51e20f10b
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/47b8be7d7bb2403381b9a0c331543c8f
Autor:
Shengjun Tan, Huijing Ma, Jinbo Wang, Man Wang, Mengxia Wang, Haodong Yin, Yaqiong Zhang, Xinying Zhang, Jieyu Shen, Danyang Wang, Graham L. Banes, Zhihua Zhang, Jianmin Wu, Xun Huang, Hua Chen, Siqin Ge, Chun-Long Chen, Yong E. Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Transposons are accepted as evolutionary catalysts but how they do so remains less clear. Analyzing 100 animal genomes finds that terminal inverted repeat-type transposable elements catalyze new gene structures and new genes in animals via both trans
Externí odkaz:
https://doaj.org/article/d0c74725b7ea4be5939fc979ebf4da85
Autor:
Ming-Jun Shi, Xiang-Yu Meng, Jacqueline Fontugne, Chun-Long Chen, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-20 (2020)
Abstract Background APOBEC-driven mutagenesis and functional positive selection of mutated genes may synergistically drive the higher frequency of some hotspot driver mutations compared to other mutations within the same gene, as we reported for FGFR
Externí odkaz:
https://doaj.org/article/cbca6501062d4301ac4a0f78154a9a04
Autor:
Alexy Promonet, Ismaël Padioleau, Yaqun Liu, Lionel Sanz, Anna Biernacka, Anne-Lyne Schmitz, Magdalena Skrzypczak, Amélie Sarrazin, Clément Mettling, Maga Rowicka, Krzysztof Ginalski, Frédéric Chedin, Chun-Long Chen, Yea-Lih Lin, Philippe Pasero
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
While R-loops can alter cell homeostasis, it is unclear what determines their toxicity. Here, the authors, by using Top1 knockdown as a tool to enhance the formation of R-loops at certain genomic sites, reveal and characterize a proportion of R-loops
Externí odkaz:
https://doaj.org/article/bd1932962b864455ac3b032015f1a0ac